nooglutil
- CAS No.
- 112193-35-8
- Chemical Name:
- nooglutil
- Synonyms
- ONK-10;Nooglutyl;nooglutil;N-(5-hydroxynicotinoyl)-L-glutamic acid;N-[(5-Hydroxypyridin-3-yl)carbonyl]-L-glutamic acid;N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid;L-GlutaMic acid, N-[(5-hydroxy-3-pyridinyl)carbonyl]-
- CBNumber:
- CB01328897
- Molecular Formula:
- C11H12N2O6
- Molecular Weight:
- 268.22
- MDL Number:
- MFCD00872338
- MOL File:
- 112193-35-8.mol
| Boiling point | 704.7±60.0 °C(Predicted) |
|---|---|
| Density | 1.514±0.06 g/cm3(Predicted) |
| pka | 3.15±0.10(Predicted) |
| FDA UNII | 09UM5JOS3W |
nooglutil Chemical Properties,Uses,Production
Uses
N-(5-hydroxynicotinoyl)-L-glutamic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
A solution of 233 g (5.83 mol) of NaOH in 930 mL of water was added to 345 g of the raw diethyl ester 15 ina 3-L one-neck flask, and the mixture was stirred a troom temperature for 2 h, after which 30 g of activated carbon was added, and stirring was continued for an additional 30 min and filtered on a Buchner funnel tor remove the activated carbon. The filtrate was made acidic (pH 4) by adding 545 mL of conc. HCl and stirred for 1 h. The precipitate was filtered off (Schott filter no. 3), washed with water (3 ?á 600 mL), suspended in 750 mL of water, acidified to pH 4 with 65 mL of conc. HCl, and immediately neutralized to pH 8 with 90 mL of 40% NaOH. Activated carbon, 13 g, was then added, and the mixture was stirred for 30 min, the activated carbon was removed by filtration, and the filtrate was acidified to pH 4 with conc. HCl. The precipitate was filtered off, washed with water (3 ?á 500 mL), and dried at 55 ??C and a vacuum of 40 mmHg for 12 h to obtain 129 g (70%) of the target product, purity by HPLC 99.61%, main substance content by titration 80% (water 21%).
nooglutil Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HangZhou RunYan Pharma Technology Co.,LTD. | +86-88660901 +86-18112526015 | sales@runyanpharma.com | China | 326 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Hebei Bonster Technology Co.,Limited | +8613315996897 | bsterltd.wendy@gmail.com | China | 796 | 58 |
| Hebei Runbin Biotechnology Co. LTD | 13180553332 | 2179877681@qq.com | CHINA | 996 | 58 |
| WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | +8615377521700 | wangwendy93@gmail.com | China | 868 | 58 |
| Hebei Henghe Import and Export Trading Co. LTD | +8618032935937 18032916000 | demi@hbtycoon.com | CHINA | 449 | 58 |
View Lastest Price from nooglutil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-08 | nooglutil
112193-35-8
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd | |
 |
2024-02-22 | Nooglutil
112193-35-8
|
US $1.00 / g | 1g | 99% | 1000kgs/month | Hubei Langyou International Trading Co., Ltd | |
 |
2023-11-27 | nooglutil
112193-35-8
|
US $1080.00 / kg | 1kg | 99% min | 20 tons | Wuhan Senwayer Century Chemical Co.,Ltd |