ChemicalBook
Chinese Japanese Germany

Pentafluorophenol

Description Reference
Pentafluorophenol
Pentafluorophenol
CAS No.
771-61-9
Chemical Name:
Pentafluorophenol
Synonyms
PFP;HOPFP;PFP-OH;C6F5OH;Pentafluorophe;SSI(R) Unions;PERFLUOROPHENOL;Pentaflurophenol;PENTAFLUORPHENOL;PENTAFLUOROPHENOL
CBNumber:
CB0135306
Molecular Formula:
C6HF5O
Formula Weight:
184.06
MOL File:
771-61-9.mol

Pentafluorophenol Properties

Melting point:
34-36 °C(lit.)
Boiling point:
143 °C(lit.)
Density 
1.757
refractive index 
1.4270
Flash point:
162 °F
storage temp. 
Store in dark!
form 
Low Melting Crystalline Solid
Specific Gravity
1.757
color 
White to almost white
Water Solubility 
soluble
BRN 
1912584
Stability:
Stable. Incompatible with strong oxidizing agents, bases, acid chlorides, acid anhydrides.
InChIKey
XBNGYFFABRKICK-UHFFFAOYSA-N
CAS DataBase Reference
771-61-9(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, pentafluoro-(771-61-9)
EPA Substance Registry System
Phenol, pentafluoro-(771-61-9)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,T,C,Xn
Risk Statements  36/37/38-34-20/21/22-63-43-23/24/25-45-67-40
Safety Statements  26-36-45-36/37/39-36/37-24/25-23-53
RIDADR  2811
WGK Germany  3
RTECS  SM6680000
3
Hazard Note  Toxic/Irritant
TSCA  T
HazardClass  8
PackingGroup  III
HS Code  29081000
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning P280,P302+P352, P312, P322, P363,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Pentafluorophenol price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 103799 Pentafluorophenol ReagentPlus , ≥99% 771-61-9 5g $32.4 2018-11-13 Buy
Sigma-Aldrich 103799 Pentafluorophenol ReagentPlus , ≥99% 771-61-9 10g $59.9 2018-11-13 Buy
TCI Chemical P0919 Pentafluorophenol >98.0%(GC)(T) 771-61-9 10g $47 2018-11-22 Buy
TCI Chemical P0919 Pentafluorophenol >98.0%(GC)(T) 771-61-9 25g $82 2018-11-22 Buy
Alfa Aesar A15574 Pentafluorophenol, 99% 771-61-9 25g $106 2018-11-13 Buy

Pentafluorophenol Chemical Properties,Uses,Production

Description

Pentafluorophenol can be used for the preparation of penta-fluorophenyl esters for peptide synthesis. It is used in the preparation of pentafluorophenyl esters for peptide synthesis and vulcanized polymers. It is also used for peptide coupling and heterocyclic acid derivatives. It is involved in the preparation of pentafluorophenyl formate which acts as a formulating agent for amines and amino acids. It can be used for synthesizing novel reagents which can achieve highly diastereoselective acetal cleavage.

Reference

3. Ishihara, Kazuaki, N. Hanaki, and H. Yamamoto. "Highly diastereoselective acetal cleavages using novel reagents prepared from organoaluminum and pentafluorophenol" Cheminform 25.9(2010):no-no.

Chemical Properties

White solid

Uses

Used for the preparation of pentafluorophenyl esters for peptide synthesis

Purification Methods

It is a hygroscopic low melting solid not freely soluble in H2O. Purify it by distillation, preferably in a vacuum [Forbes et al. J Chem Soc 2019 1959, IR and pKa: Birchall & Haszeldine J Chem Soc 13 1959]. IRofafilmhas max 3600 (OH) and 1575 (fluoroaromatic breathing) cm-1 . The benzoyl derivative has m 74-75o, 3,4-dinitrobenzoyl derivative has m 107o, the tosylate has m 64-65o (from EtOH) and the K salt crystallises from Me2CO, m 242o(dec), with 1H2O-salt the m is 248o(dec) and the 2H2O-salt has m 245o(dec). [Beilstein 6 IV 782.]

Pentafluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products


Pentafluorophenol Suppliers

Global( 315)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Jiangsu Qingquan Chemical Co., Ltd.
+86-571-86589381/86589382/86589383
lyy@qqpharm.com sales1@qqpharm.com CHINA 177 55
Dongfan Chem. Co., Ltd.
021-34500607 13391355195
021-33321290 sales@dfanchem.com CHINA 61 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Hi-Tech Chemistry Corp
0519-86626038
yuhh@hitechem.com CHINA 811 58
Dalian Richfortune Chemicals Co., Ltd
86-411-84820922, 84821539
86-411-84821380 sales@richfortunechem.com China 362 57
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1374 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Fluoropharm Co., Ltd.
+8613336034509
sales@fluoropharm.com CHINA 735 60

View Lastest Price from Pentafluorophenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-09 Pentafluorophenol
771-61-9
US $1.00 / KG 1KG 99% Customized career henan chemical co

Pentafluorophenol Spectrum


771-61-9(Pentafluorophenol)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved