ChemicalBook
Chinese Japanese Germany Korea

Pentafluorophenol

Description Reference
Pentafluorophenol
Pentafluorophenol structure
CAS No.
771-61-9
Chemical Name:
Pentafluorophenol
Synonyms
PFP;HOPFP;PFP-OH;C6F5OH;Pentafluorophe;SSI(R) Unions;PERFLUOROPHENOL;Pentaflurophenol;PENTAFLUORPHENOL;PENTAFLUOROPHENOL
CBNumber:
CB0135306
Molecular Formula:
C6HF5O
Formula Weight:
184.06
MOL File:
771-61-9.mol

Pentafluorophenol Properties

Melting point:
34-36 °C (lit.)
Boiling point:
143 °C (lit.)
Density 
1.757
refractive index 
1.4270
Flash point:
162 °F
storage temp. 
Store below +30°C.
form 
Low Melting Crystalline Solid
pka
5.50±0.33(Predicted)
color 
White to almost white
Specific Gravity
1.757
Water Solubility 
soluble
BRN 
1912584
Stability:
Stable. Incompatible with strong oxidizing agents, bases, acid chlorides, acid anhydrides.
InChIKey
XBNGYFFABRKICK-UHFFFAOYSA-N
CAS DataBase Reference
771-61-9(CAS DataBase Reference)
FDA UNII
A2YCF0YUHA
NIST Chemistry Reference
Phenol, pentafluoro-(771-61-9)
EPA Substance Registry System
Pentafluorophenol (771-61-9)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H312-H315-H319-H335-H336-H351-H373
Precautionary statements  P280-P304+P340-P405-P501a-P261-P281-P305+P351+P338
Hazard Codes  Xi,T,C,Xn
Risk Statements  36/37/38-34-20/21/22-63-43-23/24/25-45-67-40
Safety Statements  26-36-45-36/37/39-36/37-24/25-23-53
RIDADR  2811
WGK Germany  3
RTECS  SM6680000
3
Hazard Note  Toxic/Irritant
TSCA  T
HazardClass  8
PackingGroup  III
HS Code  29081000
Toxicity LD50 scu-rat: 322 mg/kg IZSBAI 3,91,65

Pentafluorophenol price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 103799 Pentafluorophenol ReagentPlus , ≥99% 771-61-9 5g $35.1 2021-03-22 Buy
Sigma-Aldrich 8.18100 Pentafluorophenol for synthesis 771-61-9 5 g $36.63 2021-03-22 Buy
Sigma-Aldrich 103799 Pentafluorophenol ReagentPlus , ≥99% 771-61-9 10g $64.8 2021-03-22 Buy
Sigma-Aldrich 8.18100 Pentafluorophenol for synthesis 771-61-9 25 g $136.9 2021-03-22 Buy
Sigma-Aldrich 8.18100 Pentafluorophenol for synthesis 771-61-9 100 g $394.05 2021-03-22 Buy

Pentafluorophenol Chemical Properties,Uses,Production

Description

Pentafluorophenol can be used for the preparation of penta-fluorophenyl esters for peptide synthesis. It is used in the preparation of pentafluorophenyl esters for peptide synthesis and vulcanized polymers. It is also used for peptide coupling and heterocyclic acid derivatives. It is involved in the preparation of pentafluorophenyl formate which acts as a formulating agent for amines and amino acids. It can be used for synthesizing novel reagents which can achieve highly diastereoselective acetal cleavage.

Reference

3. Ishihara, Kazuaki, N. Hanaki, and H. Yamamoto. "Highly diastereoselective acetal cleavages using novel reagents prepared from organoaluminum and pentafluorophenol" Cheminform 25.9(2010):no-no.

Chemical Properties

White solid

Uses

Used for the preparation of pentafluorophenyl esters for peptide synthesis

Synthesis Reference(s)

The Journal of Organic Chemistry, 54, p. 5502, 1989 DOI: 10.1021/jo00284a022

Safety Profile

scu-rat LD50:322 mg/kg IZSBAI 3,91,65

Purification Methods

It is a hygroscopic low melting solid not freely soluble in H2O. Purify it by distillation, preferably in a vacuum [Forbes et al. J Chem Soc 2019 1959, IR and pKa: Birchall & Haszeldine J Chem Soc 13 1959]. IRofafilmhas max 3600 (OH) and 1575 (fluoroaromatic breathing) cm-1 . The benzoyl derivative has m 74-75o, 3,4-dinitrobenzoyl derivative has m 107o, the tosylate has m 64-65o (from EtOH) and the K salt crystallises from Me2CO, m 242o(dec), with 1H2O-salt the m is 248o(dec) and the 2H2O-salt has m 245o(dec). [Beilstein 6 IV 782.]

Pentafluorophenol Preparation Products And Raw materials

Raw materials

Preparation Products


Pentafluorophenol Suppliers

Global( 407)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20918 58
Hi-Tech Chemistry Corp
0519-86626038
yuhh@hitechem.com CHINA 811 58
Dongfan Chem. Co., Ltd.
021-34500607 13391355195
021-33321290 sales@dfanchem.com CHINA 61 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Shanghai Time Chemicals CO., Ltd.
+8618017249410 +86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1365 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Fluoropharm Co., Ltd.
+8613336034509
+86 0571-85586753 sales@fluoropharm.com China 982 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135
sales@nbinno.com CHINA 925 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
+86 0531-67809011 sales@sdzschem.com CHINA 2941 58

View Lastest Price from Pentafluorophenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-09-29 Pentafluorophenol
771-61-9
US $0.00-0.00 / Kg/Drum 1KG 99% 500kg/month WUHAN FORTUNA CHEMICAL CO., LTD
2021-08-20 Pentafluorophenol
771-61-9
US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
2021-07-13 Pentafluorophenol
771-61-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

Pentafluorophenol Spectrum


771-61-9(Pentafluorophenol)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved