Erucamide
- CAS No.
- 112-84-5
- Chemical Name:
- Erucamide
- Synonyms
- ERUCAMIDE;13-DOCOSENAMIDE;ERUCYLAMIDE;13Z-DOCOSENAMIDE;(z)-13-docosenamide;(Z)-docos-13-enamide;ERUCIC AMIDE;CIS-13-DOCOSENOAMIDE;Erucic acid amide;CIS-13-DOCOSENAMIDE
- CBNumber:
- CB0136080
- Molecular Formula:
- C22H43NO
- Molecular Weight:
- 337.58
- MDL Number:
- MFCD00882379
- MOL File:
- 112-84-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 75-85 °C 79-81 °C (lit.) |
|---|---|
| Boiling point | 473.86°C (rough estimate) |
| Density | 0.9417 (rough estimate) |
| vapor pressure | 0-0Pa at 25℃ |
| refractive index | 1.5614 (estimate) |
| Flash point | 230 °C |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to at lease 40 mg/ml) or in Water (up to at least 25 mg/ml with warming) |
| form | solid |
| pka | 16.61±0.40(Predicted) |
| color | Off-white |
| Water Solubility | PRACTICALLY INSOLUBLE |
| Henry's Law Constant | 3.5×100 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions |
VISCOSITY CONTROLLING OPACIFYING |
| InChI | 1S/C22H43NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h9-10H,2-8,11-21H2,1H3,(H2,23,24)/b10-9- |
| InChIKey | UAUDZVJPLUQNMU-KTKRTIGZSA-N |
| SMILES | [H]\C(CCCCCCCC)=C(/[H])CCCCCCCCCCCC(N)=O |
| LogP | 8 |
| CAS DataBase Reference | 112-84-5(CAS DataBase Reference) |
| Indirect Additives used in Food Contact Substances | ERUCAMIDE |
| FDA 21 CFR | 175.105; 176.180; 177.1200;177.1210; 177.1350; 178.3860;179.45 |
| EWG's Food Scores | 1 |
| FDA UNII | 0V89VY25BN |
| NIST Chemistry Reference | 13-Docosenamide, (z)-(112-84-5) |
| EPA Substance Registry System | 13-Docosenamide, (13Z)- (112-84-5) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29241990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazardous Substances Data | 112-84-5(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Erucamide price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3088 | Plastic Additive 13 pharmaceutical secondary standard, certified reference material | 112-84-5 | 200MG | $234 | 2026-04-30 | Buy |
| Sigma-Aldrich | 280577 | cis-13-Docosenoamide | 112-84-5 | 5g | $58.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 90082 | Erucamide analytical standard | 112-84-5 | 25MG | $79.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1545045 | Plastic additive 13 United States Pharmacopeia (USP) Reference Standard | 112-84-5 | 100mg | $455 | 2026-04-30 | Buy |
| TCI Chemical | D1008 | Erucamide >85.0%(GC) | 112-84-5 | 25g | $35 | 2026-04-30 | Buy |
Erucamide Chemical Properties, Uses, Production
Description
Erucamide is also known as 13-Docosenamide or Erucylamide. It is in the form of white flakes or beads. It is soluble in isopropanol, slightly soluble in alcohol and acetone.1 In industry, cis-13-docosenoamide is used in the formulations of anti-adhesive agents, lubricants, and lubricant additives to reduce their friction coefficient and to make films easier to handle.2 It is used as a standard to determine fatty acid amides in polyethylene packaging film by GC/MS.3
Chemical Properties
Erucamide is a fatty acid amide derived from erucic acid, which is found in vegetable oil. It is a odorless waxy solid that can dissolve in isopropanol and has low solubility in alcohol and acetone. It is also combustible. Its molecular structure consists of a long unsaturated C22 chain and a polar amine group, which gives it strong surface polarity, a high melting point, and good thermal stability. Because of these properties, it finds extensive applications in industries such as plastics, rubber, printing, and machinery.
Uses
Erucamide is primarily used as a polymer additive, with plastic additive 21 is a plasticizer; used in preparation of natural mineral modified degradable polymer flame-retardant composite material.
Definition
Erucamide is a primary fatty amide resulting from the formal condensation of the carboxy group of erucic acid with ammonia. It is commonly used as a slip additive in the plastic manufacturing industry. It has a role as a human metabolite, a rat metabolite, a mammalian metabolite, a plant metabolite and an EC 3.1.1.7 (acetylcholinesterase) inhibitor. It is functionally related to an erucic acid.
Preparation
Erucamide is prepared by reaction of erucic acid with anhydrous ammonia. The reaction of erucic acid with anhydrous ammonia is as follows: C22H42O2 + NH3 → C22H43NO2.
General Description
Erucamide is a migratory additive that is commonly placed in polyolefin films to reduce their coefficient of friction (COF), a good attribute for high speed packaging operations.
Biological Activity
13-Docosenamide is the amide of docosenoic acid. It was first identified in the cerebrospinal fluid of sleep-deprived cats. It has also been detected in the cerebrospinal fluid of rats and humans. 13-Docosenamide causes reduced mobility and slightly lessened awareness in rats, whereas 9-octadecenamide induces physiological sleep.
References
[1] MIAO-MIAO LI . Antidepressant and anxiolytic-like behavioral effects of erucamide, a bioactive fatty acid amide, involving the hypothalamus–pituitary–adrenal axis in mice[J]. Neuroscience Letters, 2017, 640: Pages 6-12. DOI:10.1016/j.neulet.2016.12.072.
[2] LIEROP B V, CASTLE L, FEIGENBAUM A, et al. Spectra for the Identification of Additives in Food Packaging[C]. 1998: 0. DOI:10.1007/978-94-011-5222-8.
[3] https://pubchem.ncbi.nlm.nih.gov/compound/Erucylamide#section=Use-and-Manufacturing
[4] https://www.sigmaaldrich.com/catalog/product/aldrich/280577lang=de®ion=DE
[5] I. QUIJADA-GARRIDO. Desorption of Erucamide Vapor in Vacuum from Erucamide/Isotactic Polypropylene Films 1[J]. Macromolecules, 1996, 29 27: 8791-8797. DOI:10.1021/ma961065i.
Erucamide Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Zhilian New Materials Co., Ltd. | 13507965277 13507965277 | jxzlhg163@163.com | China | 10 | 58 |
| Hunan Changsha Hengchang Chemical Co., Ltd. | 0731-85070388 13217318550 | 403640359@qq.com | China | 22 | 62 |
| Huaihua Yuanyanda Biotechnology Co., Ltd | 18711085600 | 1652923704@qq.com | China | 4626 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9409 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44852 | 61 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6735 | 52 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
View Latest Price from Erucamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-10-05 | Erucamide
112-84-5
|
$33000.00-135000.00 | 1ton | 98.5% | 500ton | Luzhou JiuShe Technology Import and Export Trade Co., LTD. | |
 |
2026-10-02 | Erucamide
112-84-5
|
$75.00-100.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-10-02 | Erucamide
112-84-5
|
$800.00-1000.00 | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD |
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