ChemicalBook
Chinese Japanese Germany Korea

Venlafaxine hydrochloride

Venlafaxine hydrochloride
Venlafaxine hydrochloride structure
CAS No.
99300-78-4
Chemical Name:
Venlafaxine hydrochloride
Synonyms
Vexor;EFFEXOR;Venlift;AKOS 92111;VENLAFAXINEHCL;D,L-VENLAFAXINE;VENLAFAXINE HCL;Venlaffaxine HCL;VENLAFAXINE HCI, 99%;Effexor hydrochloride
CBNumber:
CB0136181
Molecular Formula:
C17H28ClNO2
Formula Weight:
313.86
MOL File:
99300-78-4.mol

Venlafaxine hydrochloride Properties

Melting point:
207-209°C
Flash point:
9℃
storage temp. 
Store at RT
solubility 
H2O: >10mg/mL
form 
powder
color 
white
Merck 
14,9946
InChIKey
QYRYFNHXARDNFZ-UHFFFAOYSA-N
CAS DataBase Reference
99300-78-4(CAS DataBase Reference)
FDA UNII
7D7RX5A8MO
NCI Dictionary of Cancer Terms
Effexor
EPA Substance Registry System
Cyclohexanol, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]-, hydrochloride (1:1 (99300-78-4)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07,GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370-H319
Precautionary statements  P210-P260-P280-P301+P310-P311-P305+P351+P338-P337+P313
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-36-39/23/24/25-23/24/25-11
Safety Statements  26-37/39-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  GV8872760
HS Code  29225090

Venlafaxine hydrochloride price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR1736 Venlafaxine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 99300-78-4 1g $86.2 2019-12-02 Buy
Sigma-Aldrich 1711268 Venlafaxine hydrochloride United States Pharmacopeia (USP) Reference Standard 99300-78-4 100mg $445.9 2019-12-02 Buy
TCI Chemical V0110 Venlafaxine Hydrochloride >98.0%(HPLC)(T) 99300-78-4 1g $72 2020-06-24 Buy
TCI Chemical V0110 Venlafaxine Hydrochloride >98.0%(HPLC)(T) 99300-78-4 5g $229 2020-06-24 Buy
Cayman Chemical 11567 Venlafaxine (hydrochloride) ≥98% 99300-78-4 10mg $90 2020-06-24 Buy

Venlafaxine hydrochloride Chemical Properties,Uses,Production

Description

Venlafaxine hydrochloride, a novel phenethylamine derivative, was introduced in the U.S.A. as an antidepressant. Venlafaxine is reported to be the first in the class of the second-generation of antidepressants with dual serotonidnorepinephrine reuptake inhibitory activity. Venlafaxine lacks any affinity for muscarinic, cholinergic, histaminergic and noradrenergic receptors and therefore, has an unusually favorable side effect profile compared with classical tricyclic antidepressants and shows less cardiotoxicity. In addition, venlafaxine has a rapid onset of action that makes it unique among the antidepressant agents. Other indications for venlafaxine include the treatment of obsessive and panic disorders, and obesity. Both enantiomers of venlafaxine were reported to have similar biological activity.

Chemical Properties

White Crystalline Powder

Originator

Wyeth-Ayerst (U.S.A.)

Uses

A selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant

Uses

Venlafaxine hydrochloride  is an inhibitor of reuptake of both serotonin (IC50 = 0.21 μM) and norepinephrine (IC50 = 0.64 μM). It is effective in vitro and in vivo and against human as well as rat receptors. As an antidepressant, it is properly placed in the serotonin-norepinephrine reuptake inhibitor class.[Cayman Chemical]

Uses

An inhibitor of ST and SLC6A2.

brand name

Effexor (Wyeth).

Biological Activity

Dual serotonin/noradrenalin re-uptake inhibitor that displays ~ 30-fold higher affinity for SERT than NET (K i values are 82 and 2480 nM respectively). Antidepressant; increases swimming and climbing behavior in the forced-swim test in rats.

Venlafaxine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Venlafaxine hydrochloride Suppliers

Global( 307)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21838 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3014 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 2678 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30043 58
Jinan Jianfeng Chemical Co., Ltd
15562555968
info@pharmachemm.com CHINA 304 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23977 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8406 58

View Lastest Price from Venlafaxine hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-12-27 Venlafaxine hydrochloride
99300-78-4
US $0.00-0.00 / mg 5mg 99% 2000tons Shaanxi Dideu Medichem Co. Ltd
2018-07-25 Venlafaxine hydrochloride
99300-78-4
US $100.00 / KG 1KG 98% 1T career henan chemical co

99300-78-4(Venlafaxine hydrochloride )Related Search:


Copyright 2017 © ChemicalBook. All rights reserved