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CHLOANTRANILIPROLE

Description
CHLOANTRANILIPROLE
CHLOANTRANILIPROLE structure
CAS No.
500008-45-7
Chemical Name:
CHLOANTRANILIPROLE
Synonyms
Coragen;Altacor;Rynaxpyr;DPX E2Y45;Chlorantranilipol;Clorantraniliprole;CHLOANTRANILIPROLE;Altacor, Fandachem;CHLORANTRANILIPROLE;Fandachem Altacor 35WG
CBNumber:
CB01404014
Molecular Formula:
C18H14BrCl2N5O2
Formula Weight:
483.15
MOL File:
500008-45-7.mol

CHLOANTRANILIPROLE Properties

Melting point:
approximate 225℃ (dec.)
Boiling point:
526.6±50.0 °C(Predicted)
Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
pka
10.19±0.70(Predicted)
CAS DataBase Reference
500008-45-7
FDA UNII
622AK9DH9G
EPA Substance Registry System
1H-Pyrazole-5-carboxamide, 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)- (500008-45-7)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xn
Risk Statements  22-36/37
Safety Statements  26

CHLOANTRANILIPROLE price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24140 Chlorantraniliprole 500008-45-7 10mg $45 2021-12-16 Buy
Cayman Chemical 24140 Chlorantraniliprole 500008-45-7 25mg $88 2021-12-16 Buy
TRC CRM0005 ChlorantraniliproleSolution(0.1mg/mLin1:1Acetonitrile/MeOH) 500008-45-7 1mg $165 2021-12-16 Buy
TRC C325380 Chlorantraniliprole 500008-45-7 10g $1550 2021-12-16 Buy
Medical Isotopes, Inc. 39318 Chlorantraniliprole 500008-45-7 100 mg $290 2021-12-16 Buy

CHLOANTRANILIPROLE Chemical Properties,Uses,Production

Description

Chlorantraniliprole (Rynaxpyr) is an insecticide of the ryanoid class. It is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). It is the first anthranilic diamide registered for use on turfgrass and landscape ornamentals. It is used to control a broad spectrum of pests including cabbage loopers, corn borers, Colorado potato beetle, European grapevine moth, armyworms and cutwormson a range of crops including potatoes and cotton. Its mechanism of action is through activating the insect ryanodine receptors (RyRs), further stimulating the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species.

Description

Chlorantraniliprole is an anthranilic diamide insecticide and agonist of ryanodine receptors located on the sarcoplasmic reticulum in muscle and endoplasmic reticulum in non-muscle cells. It binds to a different site than ryanodine on the receptor and stimulates the release of calcium from intracellular stores with EC50 values ranging from 40 to 50 nM for P. americana neurons and H. virescens or D. melanogaster recombinant ryanodine receptors. It is highly selective for insect over mammalian ryanodine receptors (EC50s = 14,000 nM, >100 μM, and >100 μM for C2C12 mouse, PC12 rat, and IMR32 human cells, respectively). Chlorantraniliprole is active against insects of the order Lepidoptera, including larvae of the fall armyworm (S. frugiperda), diamondback moth (P. xylostella), and tobacco budworm (H. virescens) with EC50 values of 0.02, 0.01, and 0.05 ppm, respectively, and of the orders Coleoptera, Diptera, and Isoptera. Formulations containing chlorantraniliprole have been used in agriculture to control moths, beetles, and caterpillars among other insects.

Uses

Chlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor. Used in Pesticide detection. (Solution)

Uses

Chlorantraniliprole is a pyrazolylpyridine insecticide and an activator of insect ryanodine receptor.

Definition

ChEBI: A carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes.

CHLOANTRANILIPROLE synthesis

500011-86-9
120374-68-7
74-89-5
500008-45-7
Synthesis of CHLOANTRANILIPROLE from 3-BroMo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid and 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-8-methyl- and Methylamine

CHLOANTRANILIPROLE Preparation Products And Raw materials

Raw materials

Preparation Products

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