5-Chloro-2-nitroaniline
- CAS No.
- 1635-61-6
- Chemical Name:
- 5-Chloro-2-nitroaniline
- Synonyms
- 5-CHLORO-2-NITROBENZENAMINE;oro-2-nitroaniL;TIMTEC-BB SBB003828;5-Chlor-2-nitroanilin;5-CHLORO-2-NITROANILINE;2-NITRO-5-CHLOROANILINE;5-Chloro-2-nitroamiline;Atorvastatin Impurity 146;Aniline, 5-chloro-2-nitro-;5-Chloro-2-nitrophenylamine
- CBNumber:
- CB0141336
- Molecular Formula:
- C6H5ClN2O2
- Molecular Weight:
- 172.57
- MDL Number:
- MFCD00007776
- MOL File:
- 1635-61-6.mol
- MSDS File:
- SDS
| Melting point | 125-129 °C (dec.)(lit.) |
|---|---|
| Boiling point | 200°C (rough estimate) |
| Density | 1.5610 (rough estimate) |
| refractive index | 1.5870 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | soluble in Chloroform, Methanol |
| pka | -1.46±0.25(Predicted) |
| form | Liquid |
| color | Clear colorless to light yellow |
| BRN | 2210201 |
| InChIKey | ZCWXYZBQDNFULS-UHFFFAOYSA-N |
| CAS DataBase Reference | 1635-61-6(CAS DataBase Reference) |
| FDA UNII | 656XJM4CON |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H310+H330-H373-H411 | |||||||||
| Precautionary statements | P262-P273-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310 | |||||||||
| Hazard Codes | T+,N,T | |||||||||
| Risk Statements | 26/27/28-33-51/53 | |||||||||
| Safety Statements | 28-36/37-45-61-28A | |||||||||
| RIDADR | UN 2237 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 9-23 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29214210 | |||||||||
| NFPA 704 |
|
5-Chloro-2-nitroaniline price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 269050 | 5-Chloro-2-nitroaniline 97% | 1635-61-6 | 25g | $93.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 269050 | 5-Chloro-2-nitroaniline 97% | 1635-61-6 | 5g | $55.6 | 2023-06-20 | Buy |
| TCI Chemical | C1139 | 5-Chloro-2-nitroaniline >99.0%(GC) | 1635-61-6 | 25g | $49 | 2024-03-01 | Buy |
| TCI Chemical | C1139 | 5-Chloro-2-nitroaniline >99.0%(GC) | 1635-61-6 | 250g | $236 | 2024-03-01 | Buy |
| Alfa Aesar | A11241 | 5-Chloro-2-nitroaniline, 97% | 1635-61-6 | 25g | $84.65 | 2024-03-01 | Buy |
5-Chloro-2-nitroaniline Chemical Properties,Uses,Production
Description
2-Nitro-5-chloroaniline is an important pharmaceutical and veterinary drug intermediate. It has been applied in the upgraded product of veterinary drug albendazole-fenbendazole, and has a broad market prospect.
Preparation
Add 2.46mol of 2,4-dichloronitrobenzene, 7.72mol of toluene to a 3L autoclave, seal the autoclave, replace the air with nitrogen, then pass in 14.1mol of liquid ammonia, increase the temperature to 160℃, continue the reaction for 8h, and then lower the temperature to 40℃, drain the excess ammonia gas, open the kettle, add the obtained solid-liquid mixture to 800mL of water, continue to cool to 10℃, filter, add the resulting filter cake to the water, continue beating and filtering, the obtained solid is crystallized with methanol to obtain 388g , yield 91.2%, the purity of the liquid phase external standard is 99.5%.
Chemical Properties
yellow to orange powder
Uses
5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
Uses
5-Chloro-2-nitroaniline is a useful synthetic intermediate. It can be used as a reagent to synthesize benzamide derivatives as histone deacetylase inhibitors. It is an intermediate used to synthesize 1-Nitro Febantel a Febantel impurity.
Application
5-Chloro-2-nitroaniline was used in the synthesis of 5-(4-substituted piperazin-1-yl)-2-nitroanilines and 5-(4-substituted piperazin-1-yl)benzimidazole-2-carbamates.
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.
General Description
The coupling of divinylbenzene cross-linked polystyrene with 5-chloro-2-nitroaniline followed by oxidative decyanation afforded benzophenone.
5-Chloro-2-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
1of4
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7845 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
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View Lastest Price from 5-Chloro-2-nitroaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-12-29 | 5-Chloro-2-nitroaniline
1635-61-6
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd | |
 |
2023-12-24 | 5-Chloro-2-nitroaniline
1635-61-6
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-03-06 | 5-Chloro-2-nitroaniline
1635-61-6
|
US $9.00 / KG | 1KG | 99.8% | 100tons | Hebei Guanlang Biotechnology Co,.LTD |
-
- 5-Chloro-2-nitroaniline
1635-61-6
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
-
- 5-Chloro-2-nitroaniline
1635-61-6
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 5-Chloro-2-nitroaniline
1635-61-6
- US $9.00 / KG
- 99.8%
- Hebei Guanlang Biotechnology Co,.LTD