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CAPSAZEPINE

CAPSAZEPINE
CAPSAZEPINE structure
CAS No.
138977-28-3
Chemical Name:
CAPSAZEPINE
Synonyms
CAPSAZEPINE;capasazepine;Capsazepine,98%;CAPSAZEPINE SYNTHETIC ANALOG OF C;8-dihydroxy-2H-2-benzazepine-2-carbothioamide;7;8-DIHYDROXY-2H-2-BENZAZEPINE-2-CARBOTHIOAMIDE;2-[[2-(4-Chlorophenyl)ethylamino]thiocarbonyl]-2,3,4,5-tetrahydro-1H-2-benzazepine-7,8-diol;N-[2-(CHLOROPHENYL)ETHYL]-1,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-2H-2-BENZAZEPINE-2-CARBOTHIOAMIDE;N-[2-(4-CHLOROPHENYL)ETHYL]-1,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-2H-2-BENZAZEPINE-2-CARBOTHIOAMIDE
CBNumber:
CB0144302
Molecular Formula:
C19H21ClN2O2S
Formula Weight:
376.9
MOL File:
138977-28-3.mol

CAPSAZEPINE Properties

Melting point:
155-157°C
Boiling point:
581.1±60.0 °C(Predicted)
Density 
1.350±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
methanol: soluble
pka
9.73±0.20(Predicted)
form 
solid
color 
off-white
InChIKey
DRCMAZOSEIMCHM-UHFFFAOYSA-N
CAS DataBase Reference
138977-28-3(CAS DataBase Reference)
FDA UNII
LFW48MY844
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  22-24/25-36-26
RIDADR  2811
WGK Germany  3
HazardClass  6.1(a)
PackingGroup  II

CAPSAZEPINE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C191 Capsazepine ≥98% (HPLC), solid 138977-28-3 5mg $186 2019-12-02 Buy
Sigma-Aldrich C191 Capsazepine ≥98% (HPLC), solid 138977-28-3 25mg $657 2019-12-02 Buy
Alfa Aesar J63055 Capsazepine, 99+% 138977-28-3 50mg $1244 2020-06-24 Buy
Alfa Aesar J63055 Capsazepine, 99+% 138977-28-3 10mg $272 2020-06-24 Buy
Cayman Chemical 10007518 Capsazepine ≥98% 138977-28-3 1mg $25 2020-06-24 Buy

CAPSAZEPINE Chemical Properties,Uses,Production

Chemical Properties

Light Yellow Solid

Uses

A selective vanilloid receptor antagonist (Ki=3.2uM

Definition

ChEBI: A benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of caps icin, it was the first reported capsaicin receptor antagonist.

Hazard

A poison.

Biological Activity

Selective vanilloid receptor antagonist (K i = 3.2 μ M). Inhibits carrageenan inflammation-induced hyperalgesic responses in the rat. Also activates amiloride-sensitive epithelial Na + channel ENaC δ . Also available as part of the Vanilloid TRPV1 Receptor Tocriset™ .

CAPSAZEPINE Preparation Products And Raw materials

Raw materials

Preparation Products


CAPSAZEPINE Suppliers

Global( 82)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24754 60
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com CHINA 47486 58
Antai Fine Chemical Technology Co.,Limited
+86-18503026267
info@antaichem.com CHINA 9664 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58
Mainchem Co., Ltd. +86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32444 55
Ningbo Materials-X Co., Ltd 0574-87487840-805 15888368997
0574-87485342 sales@mater-x.com China 475 55
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 821-50328103-801
86-21-50328109 3bsc@sina.com China 15880 69
Ascent Scientific 4401179829988
4402030 700 369 customerservice@ascentscientific.co.uk United Kingdom 279 60
Nanjing Chemlin Chemical Co., Ltd 025-83697070
+86-25-83453306 info@chemlin.com.cn China 19991 64

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