Trimeprazine
- CAS No.
- 84-96-8
- Chemical Name:
- Trimeprazine
- Synonyms
- alimemazine;Teralen;Teralene;Alimezine;Bayer 1219;ALIMENAZINE;TRIMEPRAZINE;Trimeperazine;dl-Trimeprazine;Methylpromazine
- CBNumber:
- CB0146078
- Molecular Formula:
- C18H22N2S
- Molecular Weight:
- 298.45
- MDL Number:
- MFCD00242597
- MOL File:
- 84-96-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 68°C |
|---|---|
| Boiling point | bp0.3 150-175° |
| Density | 1.1163 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| pka | pKa 9.00 (Uncertain) |
| Water Solubility | 0.942 mg/L |
| CAS DataBase Reference | 84-96-8 |
| FDA UNII | 76H78MJJ52 |
| NIST Chemistry Reference | Trimeprazine(84-96-8) |
| ATC code | R06AD01 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS09,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H318-H301-H411-H317 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P280-P305+P351+P338-P310 |
| Hazardous Substances Data | 84-96-8(Hazardous Substances Data) |
| REACH Registrations | Active |
Trimeprazine Chemical Properties,Uses,Production
Originator
Temaril,SKF,US,1958
Uses
antipruritic
Uses
Trimeprazine is used for treating itching during dermatitis of both allergic and nonallergic origin.
Definition
ChEBI: Trimeprazine is a member of phenothiazines.
Manufacturing Process
95% sodamide (2.77 grams) is added to a solution of phenthiazine (9.6
grams) in xylene (140 cc) at a temperature of 130°C and the mixture is
heated with reflux for 2 hours.
A 0.61 N solution (90 cc) of 1-chloro-2-methyl-3-dimethylaminopropane in
xylene is then added over 50 minutes and heating with reflux is continued for
20 hours. After cooling, the mixture is treated with water (40 cc) and N
methanesulfonic acid (70 cc). The aqueous layer is washed with ether, treated
with aqueous sodium hydroxide (density = 1.33; 10 cc) and extracted with
ether.
The extract is dried over potassium carbonate and evaporated and the residue
is distilled in vacuo. 3-(10-phenthiazinyl)-2-methyl-1-dimethylaminopropane
(12.6 grams) is collected, distilling between 150° and 175°C under a pressure
of about 0.3 mm Hg. By dissolving this base in acetone and adding ethereal
hydrogen chloride, a hydrochloride is obtained, MP 216° to 217°C.
brand name
Temaril (Allergan).
Therapeutic Function
Antipruritic
Trimeprazine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8039 | 58 |
| Shanghai BeiZhuo Biotech Co., Ltd. | 021-61119791,13386096464 | bzswkf@foxmail.com | China | 3916 | 50 |
| Shanghai Meishui Chemical Technology Co., Ltd | 021-60549325 18616193163 | China | 4518 | 56 | |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 | |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9909 | 65 |
| Artis Biotech Co. Ltd. | 18108108965 18108108965 | sales@artisbio.com | China | 2503 | 58 |
| Yantai ShengKailun Chemical Technology Co., Ltd. | 13356901049 | 3119594100@qq.com | China | 7964 | 55 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
View Lastest Price from Trimeprazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Alimemazine
84-96-8
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-02-02 | Trimeprazine
84-96-8
|
$1.00 | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2025-10-28 | Alimemazine
84-96-8
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Alimemazine
84-96-8
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- Trimeprazine
84-96-8
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Alimemazine
84-96-8
- $1520.00-2500.00
- TargetMol Chemicals Inc.
