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2-Amino-3-bromo-5-cyanopyridine

2-Amino-3-bromo-5-cyanopyridine structure

CAS No.: 477871-32-2

Chemical Name:: 2-Amino-3-bromo-5-cyanopyridine

Synonyms: 6-amino-6-bromonicotinonitrile;2-Amino-3-bromo-5-cyanopyridine;6-Amino-5-bromo-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 6-amino-5-bromo-;2-Amino-3-bromo-5-cyanopyridine ISO 9001：2015 REACH

CBNumber:: CB01471094

Molecular Formula:: C6H4BrN3

Molecular Weight:: 198.02

MDL Number:: MFCD02102412

MOL File:: 477871-32-2.mol

Last updated:2025-07-24 18:13:47

Product description	Number	Pack Size	Price
6-Amino-5-bromonicotinonitrile	A594680	500mg	$150
6-Amino-5-bromonicotinonitrile	3H37-9-Y0	1g	$104
6-Amino-5-bromonicotinonitrile >95%	043552	1g	$112
6-Amino-5-bromonicotinonitrile >95%	043552	500mg	$73
6-Amino-5-bromonicotinonitrile	OR2759	1g	$95

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2-Amino-3-bromo-5-cyanopyridine Properties

Melting point	194-195°
Boiling point	294.4±40.0 °C(Predicted)
Density	1.80±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	solid
pka	0.72±0.49(Predicted)
color	Beige
InChI	InChI=1S/C6H4BrN3/c7-5-1-4(2-8)3-10-6(5)9/h1,3H,(H2,9,10)
InChIKey	CKUQTHSGTPGGFK-UHFFFAOYSA-N
SMILES	C1=NC(N)=C(Br)C=C1C#N

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P271-P261-P280
TSCA	N
HazardClass	IRRITANT
HS Code	2933599590

2-Amino-3-bromo-5-cyanopyridine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A594680	6-Amino-5-bromonicotinonitrile	477871-32-2	500mg	$150	2021-12-16	Buy
SynQuest Laboratories	3H37-9-Y0	6-Amino-5-bromonicotinonitrile	477871-32-2	1g	$104	2021-12-16	Buy
Matrix Scientific	043552	6-Amino-5-bromonicotinonitrile >95%	477871-32-2	1g	$112	2021-12-16	Buy
Matrix Scientific	043552	6-Amino-5-bromonicotinonitrile >95%	477871-32-2	500mg	$73	2021-12-16	Buy
Apolloscientific	OR2759	6-Amino-5-bromonicotinonitrile	477871-32-2	1g	$95	2021-12-16	Buy

Product number	Packaging	Price	Buy
A594680	500mg	$150	Buy
3H37-9-Y0	1g	$104	Buy
043552	1g	$112	Buy
043552	500mg	$73	Buy
OR2759	1g	$95	Buy

2-Amino-3-bromo-5-cyanopyridine Chemical Properties,Uses,Production

Synthesis

4214-73-7

477871-32-2

The general procedure for the synthesis of 6-amino-5-bromonicotinonitrile from 2-amino-5-cyanopyridine is as follows: Step 1: To a solution of 6-aminonicotinonitrile (102 mg, 0.86 mmol) in acetic acid (2 mL) was added a solution of bromine in acetic acid (0.86 mmol). The mixture was stirred at room temperature for 2 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The crude product was purified by rapid chromatography on silica gel (eluent: hexane/ethyl acetate, 3:1, v/v) to afford the title compound 6-amino-5-bromonicotinonitrile (110 mg, 65% yield). The product characterization data are as follows: 1H-NMR (DMSO, 300 MHz): δ 8.26 (d, 1H, J = 2.0 Hz), 8.10 (d, 1H, J = 2.0 Hz), 7.24 (bs, 2H). MS (APCI Neg): m/z 196, 198.

References

[1] Patent: WO2005/90337, 2005, A1. Location in patent: Page/Page column 42-43
[2] Patent: WO2008/60907, 2008, A2. Location in patent: Page/Page column 38
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 9, p. 2073 - 2078
[4] Patent: US2015/266872, 2015, A1. Location in patent: Paragraph 0783; 0784
[5] Patent: EP3372601, 2018, A1. Location in patent: Paragraph 0743; 0744

2-Amino-3-bromo-5-cyanopyridine synthesis

Synthesis of 2-Amino-3-bromo-5-cyanopyridine from 2-Amino-5-cyanopyridine

2-Amino-3-bromo-5-cyanopyridine Preparation Products And Raw materials

Raw materials

2-Amino-5-cyanopyridine

Preparation Products

5-bromo-6-chloronicotinonitrile

2-Amino-3-bromo-5-cyanopyridine Suppliers

Global( 89)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10405	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23541	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	8025	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
Labnetwork lnc.	+86-27-50766799 +8618062016861	contact@labnetwork.com	China	19987	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
ANHUI WITOP BIOTECH CO., LTD	58
Shaanxi Dideu Medichem Co. Ltd	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Labnetwork lnc.	58
sgtlifesciences pvt ltd	58

View Lastest Price from 2-Amino-3-bromo-5-cyanopyridine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-06-25	2-Amino-3-bromo-5-cyanopyridine 477871-32-2	US $1.10 / g	1g	99.0% min	100 tons min	Shaanxi Dideu Medichem Co. Ltd
	2020-01-10	2-Amino-3-bromo-5-cyanopyridine 477871-32-2	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

2-Amino-3-bromo-5-cyanopyridine
477871-32-2
US $1.10 / g
99.0% min
Shaanxi Dideu Medichem Co. Ltd

2-Amino-3-bromo-5-cyanopyridine
477871-32-2
US $1.00 / KG
99%
Career Henan Chemical Co

2-Amino-3-bromo-5-cyanopyridine Spectrum

2-Amino-3-bromo-5-cyanopyridine(477871-32-2)¹HNMR

477871-32-2(2-Amino-3-bromo-5-cyanopyridine)Related Search:

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2-Amino-3-bromo-5-cyanopyridine 3-Pyridinecarbonitrile, 6-amino-5-bromo- 2-Amino-3-bromo-5-cyanopyridine ISO 9001：2015 REACH 6-amino-6-bromonicotinonitrile 6-Amino-5-bromo-3-pyridinecarbonitrile 477871-32-2