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ChemicalBook >> CAS DataBase List >>4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride Structure
4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride structure
CAS No.
116529-31-8
Chemical Name:
4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride
Synonyms
1,1-Dioxo-hexahydro-1l6-thiopyran-4-ylamine;1,1-Dioxo-tetrahydro-2H-thiopyran-4-amine HCl;4-aMino-1$l^{6}-thiane-1,1-dione hydrochloride;4-AMinotetrahydro-2H-thiopyran 1,1-dioxide HCl;4-Aminotetrahydrothiopyran 1,1-Dioxide HydrochL;1,1-dioxo-tetrahydrothiopyran-4-amine hydrochloride;4-AMinotetrahydrothiopyran 1,1-Dioxide Hydrochloride;1,1-Dioxo-tetrahydro-2H-thiopyran-4-amine hydrochloride;4-AMINOTETRAHYDRO-2H-THIOPYRAN 1,1-DIOXIDE HYDROCHLORIDE;Tetrahydro-2H-thiopyran-4-amine 1,1-dioxide hydrochloride
CBNumber:
CB01476307
Molecular Formula:
C5H12ClNO2S
Molecular Weight:
185.67
MDL Number:
MFCD11114559
MOL File:
116529-31-8.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:41
Product description Number Pack Size Price
4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride hydrochloride SYX00433 1g $1300
4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride A3327 200MG $46
4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride A3327 1G $134
4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride A617730 1g $140
4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride A617730 500mg $100
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4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride Properties

Melting point 289 °C
storage temp. Inert atmosphere,Room Temperature
solubility Soluble[in water]
Water Solubility Soluble in water
form powder to crystal
color White to Almost white
CAS DataBase Reference 116529-31-8
UNSPSC Code 12352119

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HS Code  2930909899

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SYX00433 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride hydrochloride 116529-31-8 1g $1300 2025-07-31 Buy
TCI Chemical A3327 4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride 116529-31-8 200MG $46 2025-07-31 Buy
TCI Chemical A3327 4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride 116529-31-8 1G $134 2025-07-31 Buy
TRC A617730 4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride 116529-31-8 1g $140 2021-12-16 Buy
TRC A617730 4-Aminotetrahydro-2H-thiopyran 1,1-Dioxide Hydrochloride 116529-31-8 500mg $100 2021-12-16 Buy
Product number Packaging Price Buy
SYX00433 1g $1300 Buy
A3327 200MG $46 Buy
A3327 1G $134 Buy
A617730 1g $140 Buy
A617730 500mg $100 Buy

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride Chemical Properties,Uses,Production

Uses

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide, HCl

Synthesis

tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate

595597-01-6

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride

116529-31-8

The general procedure for the synthesis of 4-aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride from tert-butyl (1,1-dioxidotetrahydro-2H-thiopyran-4-yl)carbamate was as follows: tert-butyl (1,1-dioxidotetrahydro-2H-thiopyran-4-yl)carbamate (3.14 g) was dissolved in ethyl acetate (110 mL) that was preheated to 50 °C, to which a solution was subsequently 4M HCl-ethyl acetate solution (30 mL) was added. The reaction mixture was stirred at room temperature for 19 hours. Upon completion of the reaction, the precipitated white crystals were collected by filtration and washed with ethyl acetate. Finally, the product was dried under reduced pressure to afford 4-aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride (2.39 g, 100% yield). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 1.93-2.11 (2H, m), 2.23 (2H, d, J=14.4 Hz), 3.08-3.21 (2H, m), 3.21-3.46 (3H, m), 8.10 (3H, br.s.).

References

[1] Patent: EP2261213, 2010, A1. Location in patent: Page/Page column 53
[2] Patent: EP1486490, 2004, A1. Location in patent: Page 45
[3] Patent: WO2008/34860, 2008, A1. Location in patent: Page/Page column 104
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 8, p. 3548 - 3571
[5] Patent: WO2008/145688, 2008, A2. Location in patent: Page/Page column 92

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride Preparation Products And Raw materials

Raw materials

4-(benzylaMino)tetrahydro-2H-thiopyran 1,1-dioxide tert-Butyl N-(1,1-dioxothian-4-yl)carbaMate Ethyl acetate Hydrochloric acid

Preparation Products

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride Suppliers

Global( 107)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Zjartschem 		+86-571 87238903 jocelynpan@zjarts.com CHINA 988 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29798 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		+8618795957998 karmelhk@126.com CHINA 2886 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 sales@sarms4muscle.com China 10473 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Zjartschem 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58

View Lastest Price from 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride pictures 2025-04-04 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride
116529-31-8
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride pictures 2019-12-26 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride
116529-31-8
 US $1.00 / KG 1KG 99% 1000KGS Career Henan Chemical Co

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride Spectrum

4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride(116529-31-8)1HNMR

116529-31-8(4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride)Related Search:

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1of4

Tetrahydro-2H-thiopyran-4-amine 1,1-dioxide hydrochloride, 4-Amino-1,1-dioxidothiane hydrochloride 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride hydrochloride 1,1-dioxo-tetrahydrothiopyran-4-amine hydrochloride 1,1-Dioxo-tetrahydro-2H-thiopyran-4-amine HCl 4-AMINOTETRAHYDRO-2H-THIOPYRAN 1,1-DIOXIDE HYDROCHLORIDE 4-AMinotetrahydro-2H-thiopyran 1,1-dioxide HCl 4-aMino-1$l^{6}-thiane-1,1-dione hydrochloride 2H-Thiopyran-4-aMine, tetrahydro-, 1,1-dioxide, hydrochloride 2H-Thiopyran-4-aMine,tetrahydro-, 1,1-dioxide, hydrochloride (1:1) 4-AMinotetrahydrothiopyran 1,1-Dioxide Hydrochloride Tetrahydro-2H-thiopyran-4-amine 1,1-dioxide hydrochloride 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride 97% 4-Aminotetrahydrothiopyran 1,1-Dioxide HydrochL 1,1-Dioxo-hexahydro-1l6-thiopyran-4-ylamine 1,1-Dioxo-tetrahydro-2H-thiopyran-4-amine hydrochloride 4-Aminotetrahydro-2H-thiopyran 1,1-dioxide hydrochloride hydrochloride 116529-31-8