TIN PROTOPORPHYRIN IX DICHLORIDE
- CAS No.
- 14325-05-4
- Chemical Name:
- TIN PROTOPORPHYRIN IX DICHLORIDE
- Synonyms
- SnPPIX;Nsc267099;TINPROTOPORPHYRIN;Tin protoporphyrin I;tin protoporphyrin IX;TIN PROTOPORPHYRIN IX DICHLORIDE;Tin Protoporphyrin IX (chloride);Tinprotoporphyrin IX,Tin protoporphyrin IX;Tin Protoporphyrin IX dichloride (NSC 267099;Stannate(2-) dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid]
- CBNumber:
- CB0148951
- Molecular Formula:
- C34H36Cl2N4O4Sn
- Molecular Weight:
- 754.29
- MDL Number:
- MFCD00216794
- MOL File:
- 14325-05-4.mol
- MSDS File:
- SDS
| storage temp. | Store at RT |
|---|---|
| solubility | Soluble to 25 mM in 1eq. NaOH and to 5 mM in DMSO |
| form | Dark red to violet solid. |
| FDA UNII | DIO3JT9G2P |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| NFPA 704 |
|
TIN PROTOPORPHYRIN IX DICHLORIDE price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16375 | Tin Protoporphyrin IX (chloride) | 14325-05-4 | 5mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 16375 | Tin Protoporphyrin IX (chloride) | 14325-05-4 | 10mg | $92 | 2024-03-01 | Buy |
| Cayman Chemical | 16375 | Tin Protoporphyrin IX (chloride) | 14325-05-4 | 25mg | $216 | 2024-03-01 | Buy |
| Cayman Chemical | 16375 | Tin Protoporphyrin IX (chloride) | 14325-05-4 | 50mg | $380 | 2024-03-01 | Buy |
| Tocris | 0747 | TinprotoporphyrinIXdichloride | 14325-05-4 | 10 | $129 | 2021-12-16 | Buy |
TIN PROTOPORPHYRIN IX DICHLORIDE Chemical Properties,Uses,Production
Uses
Tin Protoporphyrin IX Dichloride is a selective inhibitor of heme oxygenase.
Uses
Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin . While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. TIN PROTOPORPHYRIN IX DICHLORIDE(SnPPIX) is a synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). It also weakly inhibits endothelial nitric oxide synthase and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively). SnPPIX prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally. It is rapidly cleared from plasma and persists in certain tissues, including kidney, liver, and spleen. SnPPIX is commonly used as a tool to study the role of HO-1 activity in cells and in animals.[Cayman Chemical]
TIN PROTOPORPHYRIN IX DICHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3419 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc | 028-85305008 02885305008 | 2306208234@qq.com | China | 1004 | 50 |