ChemicalBook >> CAS DataBase List >>4,5-Dimethoxy-1-cyanobenzocyclobutane
4,5-Dimethoxy-1-cyanobenzocyclobutane
- CAS No.
- 35202-54-1
- Chemical Name:
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
- Synonyms
- 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile;4,5-dimethoxy-1,2-dihydrocyclobutabenzene-1-carbonitrile;3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile;NSC 154410;Ivabradine Impurity 79;Ivabradine Impurity 89;5-Dimethoxy-1-cyanobenzocyclobutane;1-Cyano-4,5-dimethoxybenzocyclobutene;4,5-Dimethoxy-1-cyanobenzocyclobutane;4,5-Dimethoxy-1-benzocyclobutenecarbonitrile>
- CBNumber:
- CB01503975
- Molecular Formula:
- C11H11NO2
- Molecular Weight:
- 189.21
- MDL Number:
- MFCD01846132
- MOL File:
- 35202-54-1.mol
Last updated:2023-09-12 17:26:57
| Melting point | 83-84 °C |
|---|---|
| Boiling point | 345.9±42.0 °C(Predicted) |
| Density | 1.18 |
| vapor pressure | 0.004Pa at 25℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO, Methanol |
| form | Solid |
| color | Light Brown |
| LogP | 1.22 at 30℃ and pH7 |
| CAS DataBase Reference | 35202-54-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312 | |||||||||
| HS Code | 2926907090 | |||||||||
| NFPA 704 |
|
4,5-Dimethoxy-1-cyanobenzocyclobutane price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D4485 | 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile >98.0%(HPLC)(N) | 35202-54-1 | 1g | $124 | 2024-03-01 | Buy |
| TCI Chemical | D4485 | 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile >98.0%(HPLC)(N) | 35202-54-1 | 5g | $438 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 57314 | 4,5-Dimethoxy-1-benzocyclobutenecarbonitrile | 35202-54-1 | 10g | $1460 | 2021-12-16 | Buy |
| AK Scientific | J98459 | 4,5-Dimethoxy-1-cyanobenzocyclobutane | 35202-54-1 | 10g | $140 | 2021-12-16 | Buy |
| Chemenu | CM157211 | 4,5-Dimethoxy-1-cyanobenzocyclobutane 95% | 35202-54-1 | 10g | $143 | 2021-12-16 | Buy |
4,5-Dimethoxy-1-cyanobenzocyclobutane Chemical Properties,Uses,Production
Uses
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile is used in the preparation of selective bradycardic agents.
Uses
4,5-Dimethoxy-1-cyanobenzocyclobutane is used in the preparation of selective bradycardic agents.
Synthesis
NaNH2 (39.0 g, 1.0 mol) was added in portions to a solution of hydrocinnamonitrile 8 (224.0 g, 0.83 mol) in liquid ammonia at -45°C, and the reaction mixture was stirred at -45 °C for 2 h. After evaporation of the excess NH3, NH4Cl (20.0 g) and water (1000 mL) were added in portions. After standing at room temperature, greyish crystals separated and were collected and recrystallised with ethanol to give 4,5-Dimethoxy-1-cyanobenzocyclobutane as a colourless powder. Yield 116.5 g (74%).
Synthesis of 4,5-Dimethoxy-1-cyanobenzocyclobutane from 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE
4,5-Dimethoxy-1-cyanobenzocyclobutane Preparation Products And Raw materials
Raw materials
(E)-3-(3,4-dimethoxyphenyl)acrylonitrile
3-(3,4-Dimethoxyphenyl)propanenitrile
3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-one
3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE
4,5-dimethoxy-2-methylbenzaldehyde
1of3
Preparation Products
Global( 252)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yutian pharmaceutical Co.,Ltd. | +undefined-0518-86098006 +undefined19851887368 | lvan.hui@jsytsw.com | China | 80 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5993 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 | alice@jndxj.com | China | 309 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
View Lastest Price from 4,5-Dimethoxy-1-cyanobenzocyclobutane manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-12 | 4,5-Dimethoxy-1-cyanobenzocyclobutane
35202-54-1
|
US $50.00 / kg | 1kg | 0.99 | 100000 | Hebei Yanxi Chemical Co., Ltd. | |
 |
2023-07-19 | 4,5-Dimethoxy-1-cyanobenzocyclobutane
35202-54-1
|
US $30.00 / KG | 1KG | 99% | 20 Tons | Wuhan wingroup Pharmaceutical Co., Ltd | |
 |
2023-04-04 | 4,5-Dimethoxy-1-cyanobenzocyclobutane
35202-54-1
|
US $0.00-0.00 / ml | 1ml | 98% | 1000L per month | Zhejiang Hengkang Pharmaceutical Co., Ltd. |
-
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
35202-54-1
- US $50.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
35202-54-1
- US $30.00 / KG
- 99%
- Wuhan wingroup Pharmaceutical Co., Ltd
-
- 4,5-Dimethoxy-1-cyanobenzocyclobutane
35202-54-1
- US $0.00-0.00 / ml
- 98%
- Zhejiang Hengkang Pharmaceutical Co., Ltd.
35202-54-1(4,5-Dimethoxy-1-cyanobenzocyclobutane)Related Search:
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1of4
4,5-Dimethoxy-1-cyanobenzocyclobutane
Bicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile,3,4-diMethoxy-
4,5-DiMethxoy-1,2-dihydrocyclobutabenzene-1-carbonitrile
2-cyclobutyl-2-(3,4-diMethoxyphenyl)acetonitrile
3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-8-carbonitrile
1,2-Dihydro-4,5-diMethoxybenzocyclobutene-1-carbonitrile
NSC 154410
1-Cyano-4,5-dimethoxybenzocyclobutene
4,5-diMethoxy-1-cyanobenzocyclobutane (For Ivabradine)
4,5-Dimethoxy-1-cyanobenzocyclobutane CAS 35202-54-1
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile>
5-Dimethoxy-1-cyanobenzocyclobutane
Ivabradine Impurity 79
3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile
4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
4,5-dimethoxy-1,2-dihydrocyclobutabenzene-1-carbonitrile
Ivabradine Impurity 89
35202-54-1