ChemicalBook >> CAS DataBase List >>(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester

(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester

CAS No.
147118-38-5
Chemical Name:
(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester
Synonyms
Statin intermediate J8 rui shu;Rosuvastatin calcium intermediate J8;(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fl...;(R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmet;(R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl;(3R,6E)-3-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl(;(R,E)-Methyl 3-((tert-butyldiMethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonaMido)pyriMidin-5-yl)-5-oxohept-6-enoate;6-Heptenoic acid,3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-o;Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(6E)-heptanoate;(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-hepte
CBNumber:
CB01504013
Molecular Formula:
C29H42FN3O6SSi
Molecular Weight:
607.81
MDL Number:
MFCD12756001
MOL File:
147118-38-5.mol
MSDS File:
SDS
Last updated:2023-07-07 13:45:15

(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester Properties

Boiling point 679.1±65.0 °C(Predicted)
Density 1.168
storage temp. 2-8°C
pka -0.94±0.10(Predicted)

SAFETY

Risk and Safety Statements

Hazard statements  H413

(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation ORS0001314 METHYL-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDINE-5-YL]-(3R)-3-(TERT-BUTYLDIMETHYLSILYLOXY)-5-OXO-(6E)-HEPTANOATE 95.00% 147118-38-5 1G $735.54 2021-12-16 Buy
Matrix Scientific 095990 (R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept-6-enoate 95+% 147118-38-5 250mg $742 2021-12-16 Buy
AK Scientific X6286 7-[4-Fluorophenyl]-6-isopropyl)-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptaneacidmethylester 147118-38-5 250mg $1051 2021-12-16 Buy
American Custom Chemicals Corporation ORS0001314 METHYL-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYL-N-METHYLSULFONYLAMINO)PYRIMIDINE-5-YL]-(3R)-3-(TERT-BUTYLDIMETHYLSILYLOXY)-5-OXO-(6E)-HEPTANOATE 95.00% 147118-38-5 5G $1130.28 2021-12-16 Buy
Matrix Scientific 095990 (R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-oxohept-6-enoate 95+% 147118-38-5 1g $1647 2021-12-16 Buy
Product number Packaging Price Buy
ORS0001314 1G $735.54 Buy
095990 250mg $742 Buy
X6286 250mg $1051 Buy
ORS0001314 5G $1130.28 Buy
095990 1g $1647 Buy

(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Heptenoic acid, 3-[[(1,1-diMethylethyl)diMethylsilyl] oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl (Methylsulfonyl)aMino]-5-pyriMidinyl]-5-oxo-, Methyl ester, (3R,6E)- (3R,6E)-3-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl( (R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl (R,E)-Methyl 3-((tert-butyldiMethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonaMido)pyriMidin-5-yl)-5-oxohept-6-enoate 6-Heptenoic acid,3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-o Rosuvastatin calcium intermediate J8 (R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmet (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(6E)-heptanoate 7-[4-Fluorophenyl]-6-isopropyl)-2-(N-methyl-N-methylsulfonyl amino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6E-heptanoic acid methyl ester Statin intermediate J8 rui shu (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-hepte (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fl... 147118-38-5 C29H42FN3O6SSi rosuvastatin intermediates