ChemicalBook >> CAS DataBase List >>2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
- CAS No.
- 1001067-09-9
- Chemical Name:
- 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
- Synonyms
- Teoc-NT;2-(TRIMETHYLSILYL)ETHYL 3-NITRO-1,2,4-TRIAZOLE-1-CARBOXYLATE;3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole;2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate;2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate;3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester;1H-1,2,4-Triazole-1-carboxylic acid, 3-nitro-, 2-(trimethylsilyl)ethyl ester;3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester 3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole Teoc-NT
- CBNumber:
- CB01570298
- Molecular Formula:
- C8H14N4O4Si
- Molecular Weight:
- 258.31
- MDL Number:
- MFCD11042686
- MOL File:
- 1001067-09-9.mol
- MSDS File:
- SDS
Last updated:2023-06-08 17:06:34
| solubility | Sol organics (CH2Cl2, THF, CH3CN, EtOAc); reacts with amines. |
|---|---|
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C8H14N4O4Si/c1-17(2,3)5-4-16-8(13)11-6-9-7(10-11)12(14)15/h6H,4-5H2,1-3H3 |
| InChIKey | BHTJYIDOVYPNKR-UHFFFAOYSA-N |
| SMILES | N1(C(OCC[Si](C)(C)C)=O)C=NC([N+]([O-])=O)=N1 |
| CAS DataBase Reference | 1001067-09-9 |
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T2544 | 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate >98.0%(T) | 1001067-09-9 | 1g | $141 | 2024-03-01 | Buy |
| TCI Chemical | T2544 | 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate >98.0%(T) | 1001067-09-9 | 5g | $484 | 2024-03-01 | Buy |
| TRC | T896133 | 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate | 1001067-09-9 | 100mg | $75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | ORS0003946 | 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate 95.00% | 1001067-09-9 | 1G | $212.42 | 2021-12-16 | Buy |
| AK Scientific | 5066AL | 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate | 1001067-09-9 | 1g | $228 | 2021-12-16 | Buy |
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Chemical Properties,Uses,Production
Physical properties
Mp (dec.) 85–86 °C.
Uses
2-(Trimethylsilyl)ethoxycarbonyl (Teoc) group is one of the most useful protecting groups for amines, which can be cleaved by fluoride ion under neutral conditions. However, 2-(trimethylsilyl)ethyl chloroformate(Teoc-Cl), which is generally used for the introduction of the Teoc protecting group in amines, is quite unstable and easy to decompose; therefore, distillation is recommended at regular intervals. On the other hand, Teoc-NT is a highly stable, nonhygroscopic crystalline material and can be stored for long periods without decomposition. Generally, carbamate formation proceeds quickly under neutral conditions, and highly pure carbamates are obtained without tedious column chromatographic purification. Furthermore, the coproduct 3-nitro-1,2,4-triazole (NT) can be recycled. It participates in the reactions of Reactions with Amines and Aminoalcohols, Amine Protection for Nucleosides, Reaction with Alcohols, etc.
Synthesis of 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate from (2-[(CHLOROCARBONYL)OXY]ETHYL)TRIMETHYLSILANE and 3-Nitro-1,2,4-triazole
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate Suppliers
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 8382 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006608290; 18621169109 | market03@meryer.com | China | 40241 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24539 | 81 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19918 | 55 |
View Lastest Price from 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
1001067-09-9
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
1001067-09-9
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
1001067-09-9(2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate)Related Search:
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole
3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester
Teoc-NT
2-(Trimethylsilyl)ethyl 3-Nitro-1H-1,2,4-triazole-1-carboxylate
3-Nitro-1H-1,2,4-triazole-1-carboxylic Acid 2-(Trimethylsilyl)ethyl Ester
3-Nitro-1-[2-(trimethylsilyl)ethoxycarbonyl]-1H-1,2,4-triazole
Teoc-NT
2-(TRIMETHYLSILYL)ETHYL 3-NITRO-1,2,4-TRIAZOLE-1-CARBOXYLATE
1H-1,2,4-Triazole-1-carboxylic acid, 3-nitro-, 2-(trimethylsilyl)ethyl ester
1001067-09-9
C8H14N4O4Si
Protection & Derivatization Reagents (for Synthesis)
Synthetic Organic Chemistry