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N-Methyl-N-(trimethylsilyl)trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Structure
N-Methyl-N-(trimethylsilyl)trifluoroacetamide structure
CAS No.
24589-78-4
Chemical Name:
N-Methyl-N-(trimethylsilyl)trifluoroacetamide
Synonyms
MSTFA;DK232;MSTFA MSTFA;MSTFA Reagent;MSTFA ACTIVATED I;MSTFA+TMCS (99:1);MSTFA ACTIVATED II;MSTFA ACTIVATED III;MSTFA with 1 % TMCS;N-Methyl-N-(trimethy
CBNumber:
CB0161574
Molecular Formula:
C6H12F3NOSi
Molecular Weight:
199.25
MDL Number:
MFCD00000411
MOL File:
24589-78-4.mol
Last updated:2023-05-15 10:43:06
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide Properties

Melting point 98-100°C
Boiling point 130132°C
Density 1.075 g/mL at 25 °C(lit.)
vapor density >1 (vs air)
vapor pressure 8.8 mm Hg ( 27 °C)
refractive index n20/D 1.383
Flash point 77 °F
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
pka -1.34±0.70(Predicted)
form Liquid
color Clear colorless to light yellow
Specific Gravity 1.076
Water Solubility reacts
Sensitive Moisture Sensitive
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
BRN 1941550
InChIKey MSPCIZMDDUQPGJ-UHFFFAOYSA-N
CAS DataBase Reference 24589-78-4(CAS DataBase Reference)
EWG's Food Scores 1
EPA Substance Registry System Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- (24589-78-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
Hazard Codes  Xi,F,T,N
Risk Statements  10-36/37/38-61-50/53-51/53
Safety Statements  26-36-37/39-16-45-53-61
RIDADR  UN 1993 3/PG 3
WGK Germany  3
RTECS  AC9800000
F  10-21
Hazard Note  Flammable
TSCA  T
HazardClass  3
PackingGroup  III
HS Code  29319090
NFPA 704
2
2 1

N-Methyl-N-(trimethylsilyl)trifluoroacetamide price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.41102 N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis 24589-78-4 2ml $74.4 2024-03-01 Buy
Sigma-Aldrich 8.41102 N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis 24589-78-4 5ml $99.8 2024-03-01 Buy
Sigma-Aldrich M-132 MSTFA Reagent ampule of 10 × 1.2?mL, analytical standard, Cerilliant? 24589-78-4 10x1.2mL $144 2024-03-01 Buy
Sigma-Aldrich 8.41102 N-Methyl-N-trimethylsilyl-trifluoroacetamide for synthesis 24589-78-4 25mL $283 2024-03-01 Buy
Sigma-Aldrich 69478 N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization, LiChropur? 24589-78-4 1mL $57.2 2024-03-01 Buy
Product number Packaging Price Buy
8.41102 2ml $74.4 Buy
8.41102 5ml $99.8 Buy
M-132 10x1.2mL $144 Buy
8.41102 25mL $283 Buy
69478 1mL $57.2 Buy

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to light yellow liquid

Uses

A new metabolite of Famprofazone in humans.

Uses

N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

Definition

ChEBI: An N-silyl compound that is N-methyltrifluoroacetamide in which the amide nitrogen is replaced by a trimethylsilyl group. N-methyl-N-(trimethylsilyl)trifluoroacetamide is a derivat sation agent used in gas chromatography/mass spectrometry applications.

General Description

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a derivatizing reagent. It can be used as alternatives to diazomethane.

Purification Methods

Fractionate the amide through a 40mm Vigreux column (p 11). Usually it contains ca 1% of methyl trifluoroacetamide and 1% of other impurities which can be removed by gas chromatography or fractionating using a spinning band column. [Donike J Chromatogr 42 103 1969, Donike J Chromatogr 103 91 1975, Beilstein 4 IV 4011.]

N-Methyl-N-(trimethylsilyl)trifluoroacetamide synthesis

10416-59-8
815-06-5
24589-78-4
Synthesis of N-Methyl-N-(trimethylsilyl)trifluoroacetamide from N,O-Bis(trimethylsilyl)acetamide and N-Methyl-2,2,2-trifluoroacetamide

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials

Raw materials

N,O-Bis(trimethylsilyl)acetamide N-Methyl-2,2,2-trifluoroacetamide

Preparation Products

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Suppliers

Global( 275)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
Hubei Co-Formula Material Tech Co., Ltd. 		+86-27-84459282 sales@cfmats.com CHINA 882 58
Supplier Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Shanghai Zheyan Biotech Co., Ltd. 		58
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
Hubei Co-Formula Material Tech Co., Ltd. 		58

View Lastest Price from N-Methyl-N-(trimethylsilyl)trifluoroacetamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Methyl-N- (trimethylsilyl) Trifluoroacetamide pictures 2023-03-08 N-Methyl-N- (trimethylsilyl) Trifluoroacetamide
24589-78-4
 US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
N-Methyl-N-(trimethylsilyl)trifluoroacetamide pictures 2023-01-16 N-Methyl-N-(trimethylsilyl)trifluoroacetamide
24589-78-4
 US $16.00 / kg 1kg 99% 5000 tons Hebei Duling International Trade Co. LTD
N-Methyl-N-(trimethylsilyl)trifluoroacetamide pictures 2022-10-10 N-Methyl-N-(trimethylsilyl)trifluoroacetamide
24589-78-4
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

N-Methyl-N-(trimethylsilyl)trifluoroacetamide Spectrum

N-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)MSN-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)1HNMRN-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)13CNMRN-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)IR1N-Methyl-N-(trimethylsilyl)trifluoroacetamide(24589-78-4)Raman

24589-78-4(N-Methyl-N-(trimethylsilyl)trifluoroacetamide)Related Search:

Thiophanate-methyl Bensulfuron methyl N-Methylacetamide Trifluoroacetamide Trifluoroacetamidine
TRIMETHYLSILANE Hexamethyldisilane Methyltriacetoxysilane Methyl acetate Methyl acrylate
Methylparaben Iodotrimethylsilane Azidotrimethylsilane Dichlorodimethylsilane Kresoxim-methyl
Methyltriethoxysilane Methyltris(methylethylketoxime)silane N-(Trimethylsilyl)acetamide Mstfa Reagent

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N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE W. 1% TMCS N-METHYL-N-(TRIMETHYLSILYL)TRIFLUORO-ACE TAMIDE, DERIVATIZATION GRADE N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACET-A MIDE, FOR GC N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAM, 10x1ML PACKSIZE N-METHYL-N-(TRIMETHYLSILYL)TRIFLUOROACETAMIDE 98% N-Methyl-N-(Trimethylsily)Trifluoroacetamide N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 98 MSTFA~N-Trimethylsilyl-N-methyltrifluoroacetamide N- Methyl-N-three Methylsilane threefluoroacetaMide N-Methyl-N-trimethylsilyltrifluoroacetamide(MSTFA) N-Methyl-N-trimethylsilyltrifluoroacetamide[trimethylsilylatingagent] Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)- n-methyl-n-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane MSTFA (Reagent Grade for Silylating) MSTFA, N-(Trifluoroacetyl)-N-(trimethylsilyl)methylamine, (N-Methyltrifluoroacetamido)trimethylsilane MSTFA (N-Methy-N-(triMethylsilyl)trifluoroacetaMide 2,2,2-TRIFLUORO-N-METHYL-N-(TRIMETHYLSILYL)-ACETAMIDE N-METHYL-N-(TRIMETHYLSILYL)TRIFLUORO N-METHYL-N-TMS-TRIFLUOROACETAMIDE N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE ACTIVATED I N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE ACTIVATED II N-METHYL-N-TRIMETHYLSILYLTRIFLUOROACETAMIDE ACTIVATED III N-METHYL-N-(TRIMETHYLSILYL)-2,2,2-TRIFLUOROACETAMIDE N-METHYLTRIMETHYLSILYLTRIFLUORACETAMIDE N-METHYLTRIMETHYLSILYLTRIFLUOROACETAMIDE N-TRIMETHYLSILYL-N-METHYL TRIFLUOROACETAMIDE MSTFA ACTIVATED I MSTFA ACTIVATED II MSTFA ACTIVATED III MSTFA activated III, N-Methyl-N-trimethylsilyltrifluoroacetamide imidazole mixture N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA 2,2,2-trifluoro-n-methyl-n-(trimethylsilyl)-acetamid MSTFA MSTFA 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide for gas chromatography N-(Trimethylsilyl)-N-methyl-2,2,2-trifluoroacetamide N-Methyl-N-trimethylsilyltrifluoracetamide N-Methyl-N-(trimethylsilyl)trifluoroacetamide,97% N-Methyl-N-(trimethylsilyl)trifluoroacetamide,N-Trimethylsilyl-N-methyl trifluoroacetamide, MSTFA N-Methyl-N-(trimethylsilyl)trifluoroacetamide 99+% N-Methyl-N-(trimethy MSTFA Reagent N-Methyl-N-triMethylsilyltrifluoroacetaMide  N-Methyl-N-(triMethylsilyl)trifluoroacetaMide, 97% 5GR 2,2,2-TRIFLUORO-N-METHYL-N-(TRIMETHYLSIL MSTFA with 1 % TMCS N-methy-N-(trimethylsilyl) trifluoroacetamide MSTFA, 5x10 ml, 25 g N-Methyl-N-trimethylsilyltrifluoroacetamide[TrimethylsilylatingAgent]> CAS24589-78-4 N-methyl-N-(trimethylsilyl)trifluoroacetamide N-Methyl-N-Trimethylsilyl Trifluoroacetamide (MSTFA) extrapure, 98% MSTFA+TMCS (99:1) MSTFA N-methyl-N- (trimethylmethyl silane) trifluoroacetamide DK232 N-Methyl-N- (trimethylsilyl)trifluoroacet N-Methyl-N-(trimethylsilyl)trifluoroacetamide,for GC derivatization N-Methyl-N-trimethylsilyltrifluoroacetamide, Trimethylsilylating Agent，≥ 90.0%