COLISTIN
- CAS No.
- 1066-17-7
- Chemical Name:
- COLISTIN
- Synonyms
- COLISTIN;kangdisu;totazina;colomycin;colimycin;Aids033059;coly-mycin;colymysins;kolimitsin;Aids-033059
- CBNumber:
- CB0169873
- Molecular Formula:
- C52H98N16O13
- Molecular Weight:
- 1155.43
- MDL Number:
- MFCD05662338
- MOL File:
- 1066-17-7.mol
Boiling point | 807.67°C (rough estimate) |
---|---|
Density | 1.1050 (rough estimate) |
refractive index | 1.6700 (estimate) |
storage temp. | Store at -20°C |
solubility | PBS (pH 7.2): 10 mg/ml |
CAS DataBase Reference | 1066-17-7 |
EWG's Food Scores | 1 |
FDA UNII | Z67X93HJG1 |
NCI Drug Dictionary | Coly-Mycin |
ATC code | A07AA10,J01XB01 |
SAFETY
Risk and Safety Statements
RIDADR | 3249 |
---|---|
HazardClass | 6.1(b) |
PackingGroup | III |
Toxicity | cat,LDLo,subcutaneous,250mg/kg (250mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGBEHAVIORAL: ATAXIABEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),Antibiotiki. Vol. 5(4), Pg. 10, 1960. |
COLISTIN price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | Y0001999 | Colistin for system suitability European Pharmacopoeia (EP) Reference Standard | 1066-17-7 | y0001999 | $152 | 2024-03-01 | Buy |
Cayman Chemical | 23487 | Colistin ≥95% | 1066-17-7 | 100mg | $285 | 2021-12-16 | Buy |
Cayman Chemical | 23487 | Colistin ≥95% | 1066-17-7 | 25mg | $89 | 2021-12-16 | Buy |
AK Scientific | 9632AJ | Colistin | 1066-17-7 | 100mg | $484 | 2021-12-16 | Buy |
AK Scientific | 9632AJ | Colistin | 1066-17-7 | 25mg | $220 | 2021-12-16 | Buy |
COLISTIN Chemical Properties,Uses,Production
Neurotoxicity and Nephrotoxicity
Colistin is an antibiotic which is being used more commonly now than when it was introduced because of its activity against multiresistant Gram-negative bacteria, especially Acinetobacter baumanii and Enterobacteriaceae producing extended spectrum β-lactamases. It had a bad reputation due to reports of neurotoxicity and nephrotoxicity. Recent studies have shown lower rates of nephrotoxicity than previously reported. However, in one of these reports, 7/42 patients with high serum creatinine values prior to colistin treatment developed renal failure.
Uses
Polymyxin E (colistin) is a complex of closely related cyclic peptides E1 and E2, with additional minor analogues. Polymyxin E is produced by Bacillus polymyxa var. colistinus, and is a highly basic, atypical cyclic peptide which incorporates the unusual amino acid, diaminobutyric acid. Head-to-tail coupling of lysine completes the macrocycle. Balancing the polar cyclic peptide is a hydrophobic tail with short chain fatty acids. Polymyxin E is a broad spectrum antibiotic active against Gram negative bacteria. The mechanism of action involves disruption of the bacterial outer membrane by a detergent-like effect.
brand name
Coly-Mycin (Monarch).
COLISTIN Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2534 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7930 | 58 |
Hebei Qige Biological Technology Co. Ltd | +86 +8618733132031 | CHINA | 1313 | 58 | |
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15394 | 58 |
View Lastest Price from COLISTIN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-09-08 | amoxicillin
1066-17-7
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | ||
2021-01-19 | amoxicillin
1066-17-7
|
US $1.00 / PCS | 1KG | 99% | 10 mt | Hebei Guanlang Biotechnology Co., Ltd. | ||
2020-01-10 | COLISTIN
1066-17-7
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
- amoxicillin
1066-17-7
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
- amoxicillin
1066-17-7
- US $1.00 / PCS
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
- COLISTIN
1066-17-7
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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