ChemicalBook >> CAS DataBase List >>Metaxalone
Metaxalone
- CAS No.
- 1665-48-1
- Chemical Name:
- Metaxalone
- Synonyms
- Zorane;AHR-438;Skelaxi;NSC2351;cl39,148;SKELAXIN;NSC 2351;NSC-2351;CL 39,148;Metaxalon
- CBNumber:
- CB0175959
- Molecular Formula:
- C12H15NO3
- Molecular Weight:
- 221.25
- MDL Number:
- MFCD00867700
- MOL File:
- 1665-48-1.mol
Last updated:2024-04-15 18:41:30
| Melting point | 121-1230C |
|---|---|
| Boiling point | 225°C/1.5mmHg(lit.) |
| Density | 1.1514 (rough estimate) |
| refractive index | 1.5200 (estimate) |
| Flash point | 9 °C |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO: ≥2mg/mL (warmed to 60 °C) |
| form | powder |
| pka | 12.26±0.40(Predicted) |
| color | white to tan |
| BCS Class | 2 |
| InChIKey | IMWZZHHPURKASS-UHFFFAOYSA-N |
| CAS DataBase Reference | 1665-48-1(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 1NMA9J598Y |
| NIST Chemistry Reference | Metaxalone(1665-48-1) |
| EPA Substance Registry System | 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]- (1665-48-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | F,T | |||||||||
| Risk Statements | 11-23/24/25-39/23/24/25 | |||||||||
| Safety Statements | 7-16-36/37-45 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | RQ3850000 | |||||||||
| HS Code | 2934990002 | |||||||||
| NFPA 704 |
|
Metaxalone price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR3036 | Metaxalone pharmaceutical secondary standard, certified reference material | 1665-48-1 | 500MG | $173 | 2024-03-01 | Buy |
| Sigma-Aldrich | M-074 | Metaxalone solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 1665-48-1 | 1mL | $166 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1396149 | Metaxalone United States Pharmacopeia (USP) Reference Standard | 1665-48-1 | 200mg | $174.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | M-143 | Metaxalone-D6 solution 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 1665-48-1 | 1mL | $124 | 2022-05-15 | Buy |
| TCI Chemical | M2578 | Metaxalone >98.0%(GC) | 1665-48-1 | 1g | $39 | 2024-03-01 | Buy |
Metaxalone Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Originator
Skelaxin,Robins,US,1962
Uses
For the treatment of painful peripheral musculoskeletal conditions and spasticity from upper motor neuron syndromes.
Uses
muscle relaxant (skeletal)
Uses
It is a muscle relaxant used to relax muscles and relieve pain
Uses
Metaxalone is a skeletal muscle relaxant that has applications in reducing muscle spasm, limitations in normal motion, and pain caused by musculoskeletal conditions. It is commonly used in combination with analgesics to address low back pain. The molecular or cellular actions of metaxalone is not known.[Cayman Chemical]
Definition
ChEBI: Metaxalone is an aromatic ether.
Manufacturing Process
Urea (118 g, 1.96 mols) was added to 192 g (0.98 mol) of 3-(3',5'- dimethylphenoxy)-1,2-propane-diol which had previously been heated to 150°C. The reaction mixture was then heated rapidly to 195° to 200°C and maintained at this temperature for 5 hours with constant stirring. The resulting mixture was partitioned between water and ethyl acetate and the ethyl acetate layer was dried over sodium sulfate and concentrated. The residue was distilled in vacuo and the fraction boiling at 220° to 225°C/1.5 mm was collected. Yield, 172 g (79%). The distillate was crystallized from dry ethyl acetate; MP, 121.5° to 123°C.
Therapeutic Function
Muscle relaxant
Metaxalone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 212)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8618829768577 | gao490372054@gamil.com | China | 1250 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +8619164747840 | 13119157289@163.com | China | 2971 | 58 |
| Shanghai Affida new material science and technology center | +undefined15081010295 | 2691956269@qq.com | China | 359 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
View Lastest Price from Metaxalone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-15 | Metaxalone
1665-48-1
|
US $0.00-0.00 / KG | 1KG | 99 | 100KG | Shanghai Affida new material science and technology center | |
 |
2021-08-12 | Metaxalone
1665-48-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2021-07-02 | Metaxalone
1665-48-1
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Metaxalone
1665-48-1
- US $0.00-0.00 / KG
- 99
- Shanghai Affida new material science and technology center
-
- Metaxalone
1665-48-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Metaxalone
1665-48-1
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
1665-48-1(Metaxalone)Related Search:
1of4
5-[(3,5-dimethylphenoxy)methyl]oxazolidin-2-one
2-Oxazolidinone, 5-((3,5-xylyloxy)methyl)-
2-Oxazolidinone, 5-[(3,5-dimethylphenoxy)methyl]-
5-((3,5-dimethylphenoxy)methyl)-2-oxazolidinon
5-((3,5-Dimethylphenoxy)methyl)-2-oxazolidinone
5-((3,5-xylyloxy)methyl)-2-oxazolidinon
5-((3,5-Xylyloxy)methyl)-2-oxazolidinone
5-(3,5-Xyloloxymethyl)oxazolidin-2-one
5-[(3,5-Dimethylphenoxy)methyl]-1,3-oxazolidin-2-one
AHR-438
CL 39,148
cl39,148
Metaxalon
Metazalone
Metazolone
Methaxalonum
Methoxolone
Zorane
5-(3,5-xylyloxymethyl)-2-oxazolidone
Metaxalowe
METAXALONE
METAXALONE-D6
METAXOLONE
SKELAXIN
METAXALONE 99.0%
Metaxolene(DCPDAcetate)
Skelaxi
5-[(3,5-Dimethylphenoxy)methyl]oxazolidin-2-one-d6
AHR-438-d6
Skelaxin-d
5-(3,5-Dimethylphenoxy)methyl-2-Oxazolidinone(Metaxalone)
Skelaxin-d6
Metaxalone solution
NSC 170959
Metaxalone-D6 solution
Metaxalone (200 mg)
(5R)-5-(3,5-diMethylphenoxyMethyl)-1,3-oxazolidin-2-one
Metaxalone-D
AHR438;NSC170959;SKELAXIN
Metaxalone >
Metaxalone USP/EP/BP
Metaxalone (AHR438
MetaxaloneQ: What is
Metaxalone Q: What is the CAS Number of
Metaxalone Q: What is the storage condition of
Metaxalone Q: What are the applications of
Metaxalone
Metaxalone (1396149)
NSC 2351
NSC2351
NSC-2351
Beauty he methadone
Methaxadone
Metaxalone, ≥ 98.0%
1665-48-1
1665-45-1
C12H9D6NO3
SKELAXON
Various Metabolites and Impurities
Metabolites & Impurities
Isotope Labeled Compounds
Isotope Labelled Compounds