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L-KAWAIN

L-KAWAIN Structure
L-KAWAIN structure
CAS No.
500-64-1
Chemical Name:
L-KAWAIN
Synonyms
KAWAIN;gonosan;L-KAWAIN;Nsc112162;(R)-KAWAIN;(R)-(+)-Kavain;Kawain (200 mg);L-KAWAIN USP/EP/BP;5,6-Dihydro-4-methoxy-6-styryl-2-pyron;5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one
CBNumber:
CB0182759
Molecular Formula:
C14H14O3
Molecular Weight:
230.26
MDL Number:
MFCD00467093
MOL File:
500-64-1.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00
Request For Quotation

L-KAWAIN Properties

Melting point 142-148℃
alpha D20 +105° (abs alc)
Boiling point bp0.1 195-197°
Density 1.1914 (rough estimate)
refractive index 1.5557 (estimate)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form Solid
color White to Light Yellow
Stability Light Sensitive
LogP 0.784 (est)
EWG's Food Scores 1
FDA UNII W1ES06373M

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HS Code  2932202000

L-KAWAIN price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 26524 Kavain 500-64-1 50mg $78 2024-03-01 Buy
Cayman Chemical 26524 Kavain 500-64-1 100mg $139 2024-03-01 Buy
Cayman Chemical 26524 Kavain 500-64-1 10mg $32 2024-03-01 Buy
TRC K145700 Kawain 500-64-1 100mg $160 2021-12-16 Buy
TRC K145700 Kawain 500-64-1 200mg $265 2021-12-16 Buy
Product number Packaging Price Buy
26524 50mg $78 Buy
26524 100mg $139 Buy
26524 10mg $32 Buy
K145700 100mg $160 Buy
K145700 200mg $265 Buy

L-KAWAIN Chemical Properties,Uses,Production

Originator

Largon,Klinge

Uses

Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction.

Definition

ChEBI: Kawain is a member of 2-pyranones and an aromatic ether.

Manufacturing Process

To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g bromosuccinimide. After cooling to the mixture was added 300 ml of carbon tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid, 700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared (R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C, yield 60-70%.

Therapeutic Function

Anesthetic; Tranquilizer

L-KAWAIN synthesis

14371-10-9
87830-18-0
500-64-1
Synthesis of L-KAWAIN from trans-Cinnamaldehyde and 2-Butenoic acid, 4-bromo-3-methoxy-, ethyl ester, (2Z)-

L-KAWAIN Preparation Products And Raw materials

Raw materials

N-Bromosuccinimide ZINC Ethyl acetoacetate

Preparation Products

L-KAWAIN Suppliers

Global( 101)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Shanghai Standard Technology Co., Ltd. 		18502101150 ft-sales@nature-standard.com CHINA 1923 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 47465 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Neostar United (Changzhou) Industrial Co., Ltd. 		+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10326 58
Supplier Advantage
Chengdu Biopurify Phytochemicals Ltd.
58
Henan Tianfu Chemical Co.,Ltd. 		55
Hubei Jusheng Technology Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Shanghai Standard Technology Co., Ltd. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Neostar United (Changzhou) Industrial Co., Ltd. 		58
Wuhan ChemNorm Biotech Co.,Ltd. 		58
Hubei Ipure Biology Co., Ltd 		58

View Lastest Price from L-KAWAIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-KAWAIN pictures 2023-11-27 L-KAWAIN
500-64-1
 US $0.00-0.00 / mg 5mg 99% 40kg Wuhan Senwayer Century Chemical Co.,Ltd
Kawain pictures 2023-02-24 Kawain
500-64-1
 US $0.00 / mg 20mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
L-KAWAIN pictures 2020-02-18 L-KAWAIN
500-64-1
 US $7.00 / KG 1KG 99% 100kg Career Henan Chemical Co
  • L-KAWAIN pictures
  • L-KAWAIN
    500-64-1
  • US $0.00-0.00 / mg
  • 99%
  • Wuhan Senwayer Century Chemical Co.,Ltd
  • Kawain pictures
  • Kawain
    500-64-1
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
  • L-KAWAIN pictures
  • L-KAWAIN
    500-64-1
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co

L-KAWAIN Spectrum

L-KAWAIN(500-64-1)1HNMR

500-64-1(L-KAWAIN)Related Search:

Tetracaine hydrochloride Aconitine VERATRIDINE TETRODOTOXIN QX-314
5-(4-Chlorophenyl)-furan-2-carboxylic acid 3,5
-dimethoxyphenylamide CLINODISIDE A N-(4-chlorophenyl)-N-(1-isopropyl-4-piperidyl)phenylacetamide monohydrochloride SDZ-201 106 (+/-) PD 85639
BATRACHOTOXIN DL-KAWAIN,KAWAIN 5,6-DIHYDRO-2H-PYRAN-2-ONE 4-phenyl-3-buten-2-ol 5,6-DIHYDRO-4-METHOXY-2H-PYRAN
5,6-DIHYDRO-4-HYDROXY-6-METHYL-2H-PYRAN-2-ONE L-KAWAIN PARASORBICACID

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6-dihydro-4-methoxy-6-styryl-(r)-2h-pyran-2-on gonosan [R-(E)]-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one 5,6-Dihydro-4-methoxy-6-styryl-2-pyron (6R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one (R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)- Nsc112162 5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one Kawain (200 mg) KAWAIN L-KAWAIN (R)-KAWAIN (r)-5,6-dihydro-4-methoxy-6-styryl-2h-pyran-2-one 4-methoxy-6-(beta-phenylvinyl)-5,6-dihydro-alpha-pyrone 5-hydroxy-3-methoxy-7-phenyl-2,6-heptadienoicacidgamma-lactone (R)-(+)-Kavain 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- L-KAWAIN USP/EP/BP (R,E)-4-Methoxy-6-styryl-5,6-dihydro-2H-pyran-2-one TIANFU-CHEM_2H-Pyran-2-one,5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- 500-64-1 γ-Aminobutyric acid Receptor,Calcium Channel,inhibit,Inhibitor,GABA Receptor,Gamma-aminobutyric acid Receptor,Na channels,Sodium Channel,Ca2+ channels,Ca channels,(+)-Kavain,(+) Kavain,Na+ channels,(+)Kavain 500-64-1 500-61-4 315-48-4 Coumarins Miscellaneous Natural Products