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2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one structure
CAS No.
27277-00-5
Chemical Name:
2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one
Synonyms
ICI 63197;PP-796 emetic;AMINOPROPYLTRIAZOLOPYRIMIDONE;2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2-azanyl-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2-Amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-on;1,2,4Triazolo1,5-apyrimidin-5(4H)-one, 2-amino-6-methyl-4-propyl-;2-Amio-6-methyl-4-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-5-one;2,4]triazolo[1,5-a]pyrimidin-5(4h)-one,2-amino-6-methyl-4-propyl-[;2-AMINO-6-METHYL-4-PROPYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-5(4H)-ONE
CBNumber:
CB0191331
Molecular Formula:
C9H13N5O
Formula Weight:
207.23
MOL File:
27277-00-5.mol

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Properties

Melting point:
161.8-163 °C
storage temp. 
Store at +4°C
solubility 
DMSO: 13 mg/mL
form 
solid
color 
white
InChIKey
UQDVRVNMIJAGRK-UHFFFAOYSA-N
CAS DataBase Reference
27277-00-5(CAS DataBase Reference)
EPA Substance Registry System
[1,2,4]Triazolo[ 1,5-a]pyrimidin-5(4H)-one, 2-amino-6-methyl-4-propyl- (27277-00-5)
SAFETY
  • Risk and Safety Statements
RIDADR  2811
WGK Germany  1
HazardClass  6.1(b)
PackingGroup  III

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I8283 ICI 63,197 ≥98% (HPLC) 27277-00-5 5mg $200 2018-11-13 Buy
Sigma-Aldrich I8283 ICI 63,197 ≥98% (HPLC) 27277-00-5 25mg $792 2018-11-13 Buy

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Chemical Properties,Uses,Production

Biological Activity

Potent phosphodiesterase (PDE) 4 inhibitor (IC 50 = 35 nM for inhibition of [ 3 H]-rolipram binding to rat brain). Antidepressant following systemic administration in vivo .

2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Preparation Products And Raw materials

Raw materials

Preparation Products


2-Amino-6-methyl-4-propyl-[1,2,4]triazolo[1,5-a]pyrimidin-5-one Suppliers

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