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ChemicalBook >> CAS DataBase List >>14,15-LEUKOTRIENE C4

14,15-LEUKOTRIENE C4

14,15-LEUKOTRIENE C4 Structure
14,15-LEUKOTRIENE C4 structure
CAS No.
75290-60-7
Chemical Name:
14,15-LEUKOTRIENE C4
Synonyms
EXC4;EOXIN C4;14,15-LTC4;14,15-LEUKOTRIENE C4;OBQVBASHEWLKCQ-PKBWNXTMSA-N;Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl-
CBNumber:
CB0196624
Molecular Formula:
C30H47N3O9S
Molecular Weight:
625.77
MDL Number:
MFCD00211501
MOL File:
75290-60-7.mol
Last updated:2023-05-21 10:59:17
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14,15-LEUKOTRIENE C4 Properties

storage temp. Store at -20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 100 μg/ml
form Liquid.

14,15-LEUKOTRIENE C4 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10011360 14,15-Leukotriene C4 ≥95% 75290-60-7 25μg $127 2024-03-01 Buy
Cayman Chemical 10011360 14,15-Leukotriene C4 ≥95% 75290-60-7 50μg $236 2024-03-01 Buy
Cayman Chemical 10011360 14,15-Leukotriene C4 ≥95% 75290-60-7 100μg $447 2024-03-01 Buy
TRC L330368 14,15-LeukotrieneC4 75290-60-7 25μg $125 2021-12-16 Buy
Product number Packaging Price Buy
10011360 25μg $127 Buy
10011360 50μg $236 Buy
10011360 100μg $447 Buy
L330368 25μg $125 Buy

14,15-LEUKOTRIENE C4 Chemical Properties,Uses,Production

Description

Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTC4 is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. 14,15-LTC4 is classified as an eoxin, because it is formed mostly by eosinophils. However, mast cells and nasal polyps can synthesize 14,15-LTC4 as well. Little is known about the physiological actions of 14,15-LTC4. It has weak contractile activity on both guinea pig ileum and pulmonary parenchyma in contrast to the effects of 5-LO-derived LTs. However, in an in vitro permeability assay, 14,15-LTC4 can increase vascular permeability of human endothelial cell monolayers, with similar potency to that of 5-LO-derived LTs resulting in plasma leakage - a hallmark of inflammation.

Uses

14,15-Leukotriene C4 is an acute inflammatory mediator.

14,15-LEUKOTRIENE C4 Preparation Products And Raw materials

Raw materials

Preparation Products

14,15-LEUKOTRIENE C4 Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Supplier Advantage
Aladdin Scientific 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Energy Chemical 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58

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14,15-LEUKOTRIENE C4 14,15-LTC4 EOXIN C4 EXC4 Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-13-carboxy-1-[(1S)-1-hydroxyhexyl]-2,4,6,9-tridecatetraen-1-yl]-L-cysteinyl- OBQVBASHEWLKCQ-PKBWNXTMSA-N 75290-60-7