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P-nitrophenyl butyrate

CAS No.
2635-84-9
Chemical Name:
P-nitrophenyl butyrate
Synonyms
4-Nitrophenol butyrate;P-NITROPHENYL BUTYRATE;4-NITROPHENYL BUTYRATE;PARA-NITROPHENYLBUTYRATE;(4-nitrophenyl) butanoate;4-Nitrophenyl butyrate >=98%;BUTYRIC ACID 4-NITROPHENYL ESTER;Butanoic acid p-nitrophenyl ester;Butanoic acid, 4-nitrophenyl ester;p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester
CBNumber:
CB0202840
Molecular Formula:
C10H11NO4
Molecular Weight:
209.2
MDL Number:
MFCD00047734
MOL File:
2635-84-9.mol
MSDS File:
SDS
Last updated:2023-11-30 11:50:35

P-nitrophenyl butyrate Properties

Boiling point 184-185 °C
Density 1.19 g/mL at 20 °C(lit.)
storage temp. -20°C
solubility chloroform: 0.1 g/mL, clear, faintly yellow
form A neat oil
BRN 1879729
InChIKey DVDUMIQZEUTAGK-UHFFFAOYSA-N
FDA UNII 42RWS6BQC4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P362+P364
Hazard Codes  Xi
Risk Statements  43
Safety Statements  36/37
WGK Germany  3
HS Code  29156000

P-nitrophenyl butyrate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N9876 4-Nitrophenyl butyrate ≥98% 2635-84-9 1g $77.6 2024-03-01 Buy
Sigma-Aldrich N9876 4-Nitrophenyl butyrate ≥98% 2635-84-9 5g $276 2024-03-01 Buy
Cayman Chemical 25439 4-Nitrophenyl Butyrate ≥95% 2635-84-9 1g $49 2024-03-01 Buy
Cayman Chemical 25439 4-Nitrophenyl Butyrate ≥95% 2635-84-9 5g $202 2024-03-01 Buy
Sigma-Aldrich N9876 4-Nitrophenyl butyrate ≥98% 2635-84-9 10g $465 2024-03-01 Buy
Product number Packaging Price Buy
N9876 1g $77.6 Buy
N9876 5g $276 Buy
25439 1g $49 Buy
25439 5g $202 Buy
N9876 10g $465 Buy

P-nitrophenyl butyrate Chemical Properties,Uses,Production

Description

P-nitrophenyl butyrate also kown as 4-nitrophenyl butyrate, is a probe for lipase activity. It is hydrolyzed by lipase in the water ambient condition, giving rise to p-nitrophenol and butyric acid. P-nitrophenol actually occurs in the anionic form, p-nitrophenolate, giving a yellowish coloration and absorbing light at 410 nm in an alkaline buffer such as Tris-HCl pH 7.5.

Uses

4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.

Definition

ChEBI: P-nitrophenyl butyrate is a butyrate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of butyric acid. It is a butyrate ester and a C-nitro compound. It is functionally related to a 4-nitrophenol.

References

[1] POHANKA M. Biosensors and Bioassays Based on Lipases, Principles and Applications, a Review.[J]. Molecules, 2019. DOI:10.3390/molecules24030616.
[2] WENTING SHANG. Enzymatic hydrolysis of p-nitrophenyl butyrate in CO2-based micelle systems[J]. Journal of chemical technology and biotechnology, 2013, 89 9: 1324-1329. DOI:10.1002/jctb.4246.
[3] SIGRUN H. STERRI Frode F Bj?rn A Johnsen. A radiochemical assay method for carboxylesterase, and comparison of enzyme activity towards the substrates methyl [1-14C] butyrate and 4-nitrophenyl butyrate[J]. Biochemical pharmacology, 1985, 34 15: Pages 2779-2785. DOI:10.1016/0006-2952(85)90579-9.
[4] BISHNU PRASAD PANDEY. Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor.[J]. BMC Complementary Medicine and Therapies, 2020: 198. DOI:10.1186/s12906-020-02989-2.

100-02-7
107-92-6
2635-84-9
Synthesis of P-nitrophenyl butyrate from 4-Nitrophenol and Butyric Acid
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View Lastest Price from P-nitrophenyl butyrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
P-NITROPHENYL BUTYRATE pictures 2020-01-01 P-NITROPHENYL BUTYRATE
2635-84-9
US $1.00 / KG 1KG 95-99% 1ton Career Henan Chemical Co
4-Nitrophenyl butyrate,p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester 4-NITROPHENYL BUTYRATE P-NITROPHENYL BUTYRATE Butanoic acid, 4-nitrophenyl ester PARA-NITROPHENYLBUTYRATE p-Nitrophenyl butyrate, Butyric acid 4-nitrophenyl ester 4-Nitrophenol butyrate Butanoic acid p-nitrophenyl ester BUTYRIC ACID 4-NITROPHENYL ESTER (4-nitrophenyl) butanoate 4-Nitrophenyl butyrate >=98% 2635-84-9 C10H11N1O4 Lipids Chromogen Enzyme Substrate Fatty Acids Biochemicals and Reagents BioChemical