ChemicalBook >> CAS DataBase List >>1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
- CAS No.
- 54280-71-6
- Chemical Name:
- 1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
- Synonyms
- Nemadipine-A;NemadipineA,Nemadipine A;Nemadipine-A - CAS 54280-71-6 - Calbiochem;1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-, 3,5-diethyl ester
- CBNumber:
- CB02097051
- Molecular Formula:
- C19H18F5NO4
- Molecular Weight:
- 419.34
- MDL Number:
- MFCD00335178
- MOL File:
- 54280-71-6.mol
Last updated:2023-06-08 09:02:50
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Properties
| storage temp. | −20°C |
|---|---|
| solubility |
DMSO:20.0(Max Conc. mg/mL);47.69(Max Conc. mM) Ethanol:15.0(Max Conc. mg/mL);35.77(Max Conc. mM) Methanol:100.0(Max Conc. mg/mL);238.46(Max Conc. mM) |
| form | Pale-yellow solid |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| NFPA 704 |
|
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21689 | Nemadipine A ≥98% | 54280-71-6 | 5mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 21689 | Nemadipine A ≥98% | 54280-71-6 | 10mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 21689 | Nemadipine A ≥98% | 54280-71-6 | 25mg | $302 | 2024-03-01 | Buy |
| Cayman Chemical | 21689 | Nemadipine A ≥98% | 54280-71-6 | 50mg | $570 | 2024-03-01 | Buy |
| TRC | N389803 | Nemadipine-A | 54280-71-6 | 5mg | $165 | 2021-12-16 | Buy |
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Chemical Properties,Uses,Production
Uses
Nemadipine-A is a cell permeable L-type calcium channel protein inhibitor.
Definition
ChEBI: Nemadipine-A is a dihydropyridine that is that is 1,4-dihydropyridine which is substituted at positions 2 and 6 by methyl groups, at positions 3 and 5 by ethoxycarbonyl groups, and at position 4 by a pentafluorophenyl group. An L-type calcium channel alpha1-subunit antagonist. When exposed to the microscopic soil nematode Caenorhabditis elegans, nemadipine-A induces a variety of defects including those affecting morphology and egg laying. It has a role as a calcium channel blocker. It is a dihydropyridine, a diester, a member of pentafluorobenzenes, an ethyl ester and a member of dicarboxylic acids and O-substituted derivatives.
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester synthesis
Synthesis of 1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester from Pentafluorobenzaldehyde and Ethyl acetoacetate
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Preparation Products And Raw materials
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester Suppliers
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
1,4-Dihydro-2,6-dimethyl-4-(pentafluorophenyl)-3,5-pyridinedicarboxylic acid diethyl ester
Nemadipine-A
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-, 3,5-diethyl ester
Nemadipine-A - CAS 54280-71-6 - Calbiochem
NemadipineA,Nemadipine A
54280-71-6
C19H18F5NO4