ChemicalBook >> CAS DataBase List >>Indole-4-carboxaldehyde

Indole-4-carboxaldehyde

CAS No.
1074-86-8
Chemical Name:
Indole-4-carboxaldehyde
Synonyms
4-INDOLECARBALDEHYDE;1H-INDOLE-4-CARBALDEHYDE;4-FLUOROINDOLE;1H-INDOLE-4-CARBOXALDEHYDE;NSC 337264;e-4-carboxaL;4-FORMYLINDOLE;INDOLE-4-ALDEHYDE;4-Formyl-1H-indole;RARECHEM AH BS 0110
CBNumber:
CB0217303
Molecular Formula:
C9H7NO
Molecular Weight:
145.16
MDL Number:
MFCD01632221
MOL File:
1074-86-8.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:31

Indole-4-carboxaldehyde Properties

Melting point 139-143 °C(lit.)
Boiling point 339.1±15.0 °C(Predicted)
Density 1.278±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form powder to crystal
pka 15.84±0.30(Predicted)
color Light yellow to Brown
Water Solubility Soluble in ethanol and acetone. Insoluble in water.
Sensitive Air Sensitive
CAS DataBase Reference 1074-86-8(CAS DataBase Reference)
NIST Chemistry Reference 1H-indole-4-carboxaldehyde(1074-86-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317-H319
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36-43
Safety Statements  26-36/37
WGK Germany  3
Hazard Note  Irritant/Keep Cold
HazardClass  IRRITANT
HS Code  29333990
NFPA 704
1
2 0

Indole-4-carboxaldehyde price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 632422 Indole-4-carboxaldehyde 97% 1074-86-8 1g $129 2023-06-20 Buy
Sigma-Aldrich 632422 Indole-4-carboxaldehyde 97% 1074-86-8 5g $628 2023-06-20 Buy
TCI Chemical I0712 Indole-4-carboxaldehyde >98.0%(GC) 1074-86-8 1g $160 2024-03-01 Buy
TCI Chemical I0712 Indole-4-carboxaldehyde >98.0%(GC) 1074-86-8 5g $400 2024-03-01 Buy
Alfa Aesar H28019 Indole-4-carboxaldehyde, 97% 1074-86-8 5g $713 2021-12-16 Buy
Product number Packaging Price Buy
632422 1g $129 Buy
632422 5g $628 Buy
I0712 1g $160 Buy
I0712 5g $400 Buy
H28019 5g $713 Buy

Indole-4-carboxaldehyde Chemical Properties,Uses,Production

Chemical Properties

White to dark brown solid

Uses

4-Indolecarbaldehyde is a synthetic intermediate used for pharmaceutical synthesis. Also used as reactant in Biginelli reaction, synthesis of aurora kinase A inhibitors, preparation of antitumor agents, intermolecular Friedel-Crafts acylation, preparation of inhibitors of cell division in E. coli and synthesis of Hantzsch pyridine-containing Schiff bases.

Uses

Indole-4-carboxaldehyde is usually used as reactant in Biginelli reaction,preparation of antitumor agents,intramolecular Friedel-Crafts acylation,preparation of inhibitors of cell division in E. Coli,synthesis of Hantzsch pyridine-containing Schiff bases.

Definition

ChEBI: Indole-4-carbaldehyde is a heteroarenecarbaldehyde that is indole in which the hydrogen at position 4 has been replaced by a formyl group. It has a role as an algal metabolite. It is a member of indoles and a heteroarenecarbaldehyde.

Synthesis Reference(s)

The Journal of Organic Chemistry, 46, p. 1752, 1981 DOI: 10.1021/jo00321a053
Tetrahedron, 39, p. 3695, 1983 DOI: 10.1016/S0040-4020(01)88608-7

General Description

Indole-4-carboxaldehyde participates in the synthesis of arcyriacyanin A. Synthesis of 4-indole-4-carboxaldehyde has been reported. Intramolecular Friedel-Crafts (FC) acylation of indole-4-carboxaldehyde has been reported.

1074-85-7
114615-82-6
1074-86-8
Synthesis of Indole-4-carboxaldehyde from INDOLE-4-METHANOL and TETRAPROPYLAMMONIUM PERRUTHENATE
Global( 301)Suppliers
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Capot Chemical Co.,Ltd.
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career henan chemical co
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View Lastest Price from Indole-4-carboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Indole-4-carboxaldehyde pictures 2021-08-12 Indole-4-carboxaldehyde
1074-86-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Indole-4-carboxaldehyde pictures 2021-07-02 Indole-4-carboxaldehyde
1074-86-8
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Indole-4-carboxaldehyde  pictures 2020-01-03 Indole-4-carboxaldehyde
1074-86-8
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
1H-indol-4-carbaldehyde 1H-indole-4-carbaldehyde(SALTDATA: FREE) INDOLE-4-CARBALDEHYDE INDOLE-4-CARBOXALDEHYDE INDOLE-4-ALDEHYDE 4-FORMYLINDOLE 4-INDOLE-CARBOXALDEHYDE Indole-4-carboxaldehyde 97% 4-Formyl-1H-indole 3-Indole Carboxyaldehyde 1H-Indole-4-carboxaldehyde (9CI) 1H-Indole-4-carboxaldehyde 98% RARECHEM AH BS 0110 NSC 337264 INDOLE-4-CARBOXALDEHYDE (4-FORMYLINDOLE) Indole-4-carboxaldehyde ,98% Indole-4-carboxaldehyde in stock Factory Indole-4-carboxaldehyde> e-4-carboxaL Indole-4-carboxaldehyde ISO 9001:2015 REACH 4-INDOLECARBALDEHYDE 1H-INDOLE-4-CARBALDEHYDE 1H-INDOLE-4-CARBOXALDEHYDE 4-FLUOROINDOLE Indole-4-carboxaldehyde (7CI, 8CI) Indol-4-carbaldehyde 1074-86-8 41074-86-8 074-86-8 Building Blocks Indoles Heterocyclic Building Blocks Simple Indoles Building Blocks Indole Indoles IndolesOxindoles Indoles and derivatives pharmacetical Heterocycle-Indole series Aldehydes blocks ALDEHYDE