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Rutaecarpine

CAS No.
84-26-4
Chemical Name:
Rutaecarpine
Synonyms
RUTECARPINE;Rutacarpine;RHETINE;Rutaecarpine;Rutaccarpine;RUTECARPINE 95+;Rutaecarpine >Rutecarpine (8CI);Rutaecarpine std.;Rutaecarpine 84-26-4
CBNumber:
CB0226965
Molecular Formula:
C18H13N3O
Molecular Weight:
287.32
MDL Number:
MFCD00210551
MOL File:
84-26-4.mol
Last updated:2023-08-24 17:20:48

Rutaecarpine Properties

Melting point 259.5-260°
Boiling point 429.62°C (rough estimate)
Density 1.2030 (rough estimate)
refractive index 1.5855 (estimate)
storage temp. Sealed in dry,2-8°C
solubility DMSO: 18 mg/mL clear yellow solution, soluble
form solid
pka 15.79±0.20(Predicted)
color white
Merck 14,8298
InChIKey ACVGWSKVRYFWRP-UHFFFAOYSA-N
CAS DataBase Reference 84-26-4(CAS DataBase Reference)
FDA UNII 8XZV289PRY

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  T
Risk Statements  25-36/37/38
Safety Statements  45-36-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  NM3454000
HS Code  29339900

Rutaecarpine price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R3277 Rutaecarpine >98% (HPLC) 84-26-4 5mg $162 2024-03-01 Buy
Sigma-Aldrich R3277 Rutaecarpine >98% (HPLC) 84-26-4 25mg $253.6 2024-03-01 Buy
TCI Chemical R0102 Rutaecarpine >98.0%(HPLC)(N) 84-26-4 200mg $220 2024-03-01 Buy
Cayman Chemical 22897 Rutaecarpine ≥98% 84-26-4 5mg $49 2024-03-01 Buy
Cayman Chemical 22897 Rutaecarpine ≥98% 84-26-4 10mg $82 2024-03-01 Buy
Product number Packaging Price Buy
R3277 5mg $162 Buy
R3277 25mg $253.6 Buy
R0102 200mg $220 Buy
22897 5mg $49 Buy
22897 10mg $82 Buy

Rutaecarpine Chemical Properties,Uses,Production

Description

This alkaloid occurs with Evodiamine (q.v.) in the Chinese drug 'Wou-chou-yu' which is the dried fruit of Evodia rutaecarpa Benth. It crystallizes from boiling EtOH as colourless, or pale yellow, needles and is optically inactive. The acetyl derivative has m.p. 184-6°C and the benzoyl compound, m.p. 194°C. The alkaloid gives a yellow colour with concentrated H2S04 and is decomposed by KOH in boiling amyl alcohol yielding anthranilic acid and 3-{3-aminoethylindole- 2-O!carboxylic acid, CllH120 2N2, silky crystals, m.p. 257°C.
Pharmacologically, the alkaloid causes increased arterial pressure on injection.

Chemical Properties

Solid

Uses

Rutaecarpine is an indole alkaloid contained in the fruit of Evodiae fruits. It been shown to ameliorate bodyweight gain through orexigenic neuropeptides NPY and AgRP. It also playes a role in the treatment of high blood pressure

Definition

ChEBI: Rutecarpine is a member of beta-carbolines.

References

Asahina, Kashiwagi., J. Pharm. Chim., 14,54 (1916)
Asahina, Mayeda.,J. Pharm. Soc., Japan, No. 416 (1916)
Asahina, Fujita., ibid, 863 (1921)
Kermack, Perkin, Robinson.,J. Chem. Soc., 119,1615 (1921)
Asahina, Manske, Robinson., ibid, 1708 (1927)
Asahina, Irie, Ohta., J. Pharm. Soc., Japan, 48, 51 (1928)
Ohta., ibid, 60, 109 (1940)
Schopf, Steuer., Annalen, 558, 124 (1947)
Biosynthesis:
Yamazaki, Ikuta., Tetrahedron Lett., 3221 (1966)
Yamazakietal., ibid, 3317 (1967)
Pharmacology:
Raymond-Hamet., Cornpt. rend., 220, 749 (1945)

1316852-05-7
84-26-4
Synthesis of Rutaecarpine from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

Rutaecarpine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 314)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 1000 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58

View Lastest Price from Rutaecarpine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Rutaecarpine pictures 2024-04-12 Rutaecarpine
84-26-4
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Rutaecarpine pictures 2023-11-27 Rutaecarpine
84-26-4
US $0.00 / kg 1kg 99% 20 tons Wuhan Senwayer Century Chemical Co.,Ltd
Rutaecarpine pictures 2023-02-24 Rutaecarpine
84-26-4
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • Rutaecarpine pictures
  • Rutaecarpine
    84-26-4
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • Rutaecarpine pictures
  • Rutaecarpine
    84-26-4
  • US $0.00 / kg
  • 99%
  • Wuhan Senwayer Century Chemical Co.,Ltd
  • Rutaecarpine pictures
  • Rutaecarpine
    84-26-4
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
:3,4]pyrido[2,1-b]quinazolin-5(7H)-one Indolo(2',3':3,4)pyrido(2,1-b)quinazolin-5(7H)-one, 8,13-dihydro- (9CI) Rutecarpine (8CI) 7,8-dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one RHETINE 8,13-DIHYDRO-INDOLO[2'3':3,4]PYRIDO[2,1-B]QUINAZOLIN-5(7H)-ONE RUTECARPINE 95+ Rutaecarpine std. Indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one,8,13-dihydro- Rutecarpine, 8,13-Dihydroindolo[2μ,3μ:3,4]pyrido[2,1-b]quinazolin-5(7H)-one 5,7,8,13-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazoline-5-one Rutaecarpine (Rutecarpine) Rutaecarpine Rutaecarpine (synthetic) Rutaecarpine, froM TetradiuM ruticarpuM Rutaecarpine, 98%, from Evodia rutaecarpa (Juss.) Benth. Rutaecarpine 84-26-4 Rutaecarpine > Rutaecarpine USP/EP/BP Rutaccarpine Rutacarpine RUTECARPINE Rutaecarpine 98%min 7,8-Dihydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one 84-26-4 84-16-4 Cell Signaling and Neuroscience Ion Channels Monovalent Ion Channels Potassium Channel Modulators Voltage-gated Ion Channels BioChemical Cell Biology chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Indoles and derivatives Inhibitors