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PP3

PP3
PP3 structure
CAS No.
5334-30-5
Chemical Name:
PP3
Synonyms
PP3;NSC 1401;PP3 - CAS 5334-30-5 - Calbiochem;4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE;4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE;1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE;4-Amino-1-phenylpyrazole[3,4-d]pyrimidine,95%;1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine;4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
CBNumber:
CB0230067
Molecular Formula:
C11H9N5
Formula Weight:
211.22
MOL File:
5334-30-5.mol

PP3 Properties

Melting point:
214-217 °C
storage temp. 
-20°C
form 
Off-white solid
λmax
240nm(H2O (pH 1))(lit.)
BRN 
198460
CAS DataBase Reference
5334-30-5(CAS DataBase Reference)

SAFETY

Hazard Codes  Xn,Xi
Risk Statements  36/37/38-22
Safety Statements  36/37/39-26
Hazard Note  Irritant
HS Code  29335995

PP3 price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2737 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine >98.0%(HPLC) 5334-30-5 200mg $34 2018-11-22 Buy
TCI Chemical A2737 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine >98.0%(HPLC) 5334-30-5 1g $103 2018-11-22 Buy
Alfa Aesar L07125 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85% 5334-30-5 5g $251 2018-11-13 Buy
Alfa Aesar L07125 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85% 5334-30-5 1g $67.4 2018-11-13 Buy
Cayman Chemical 15595 PP3 ≥98% 5334-30-5 5mg $95 2018-11-13 Buy

PP3 Chemical Properties,Uses,Production

Chemical Properties

Whit to Off-White Solid

Uses

Intermediate in the preparation of various enzymatic inhibitors

Uses

The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]

Biological Activity

Negative control for the src kinase inhibitor PP 2 (3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine ). Inhibits EGFR kinase (IC 50 = 2.7 μ M).

PP3 Preparation Products And Raw materials

Raw materials

Preparation Products


PP3 Suppliers

Global( 56)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30291 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24648 81
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 info@energy-chemical.com China 44187 61
VDM Biochemicals 0330-2528181
0330-2528171 sales@vdmbio.com United States 511 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32492 50
Shanghai Nuohey Chemical Co., Ltd. +86 (21) 52212593,51093016,13761626812,18217440778 QQ:2817342338,1658198360,934678158
+86 (21) 51062076 sales@nuohey.com China 10728 60

5334-30-5(PP3)Related Search:


  • 4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE
  • 4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE
  • 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE
  • 1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
  • PP3
  • 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
  • 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE: TECH., 85%
  • 4-Amino-1-phenylpyrazolo3,4-düpyrimidine, tech. 85%
  • 4-Amino-1-phenylpyrazole[3,4-d]pyrimidine,95%
  • 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, tech
  • PP3 - CAS 5334-30-5 - Calbiochem
  • 5334-30-5
  • AMINO
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides
  • Intracellular Signaling
  • Amines
  • 4-Amino-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine, tech. 85%
  • NSC 1401
  • 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
  • Aromatics
  • Heterocycles
  • Intermediates
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