ChemicalBook >> CAS DataBase List >>2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE structure

CAS No.: 6564-72-3

Chemical Name:: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE

Synonyms: Voglibose int;benzylglucopyranose;Tetrabenzyl glucose;Voglibose Impurity 1;Voglibose TBG IMpurity;Voglibose TBG impurities;Voglibose alpha-TBG Impurity;2,3,4,6-tetra-o-benzyl-d-glucose;6-Tetra-O-benzyl-D-glucopyranose;2,3,4,6-Tetra-o-benzyl-D-glucopyransoe

CBNumber:: CB0234449

Molecular Formula:: C34H36O6

Molecular Weight:: 540.66

MDL Number:: MFCD00066004

MOL File:: 6564-72-3.mol

Last updated:2023-11-17 11:05:57

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2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Properties

Melting point	151-156 °C
Boiling point	672.4±55.0 °C(Predicted)
Density	1.22
storage temp.	Sealed in dry,Store in freezer, under -20°C
pka	11.87±0.70(Predicted)
Water Solubility	Soluble in CHCl3. Insoluble in water.
LogP	5.9 at 20℃ and pH6.5
CAS DataBase Reference	6564-72-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

Safety Statements

22-24/25

WGK Germany

NFPA 704

	1
0		0

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	H31595	2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose, 98%	6564-72-3	1g	$55.65	2024-03-01	Buy
Alfa Aesar	H31595	2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose, 98%	6564-72-3	5g	$180.65	2024-03-01	Buy
TRC	P992030	2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose	6564-72-3	100mg	$60	2021-12-16	Buy
TRC	P992030	2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose	6564-72-3	500mg	$90	2021-12-16	Buy
Usbiological	294905	2,3,4,6-Tetra-O-benzoyl-D-glucopyranose	6564-72-3	100mg	$375	2021-12-16	Buy

Product number	Packaging	Price	Buy
H31595	1g	$55.65	Buy
H31595	5g	$180.65	Buy
P992030	100mg	$60	Buy
P992030	500mg	$90	Buy
294905	100mg	$375	Buy

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Chemical Properties,Uses,Production

Description

2,3,4,6-Tetra-O-benzyl-D-glucopyranose is a selectively protected intermediate, where the anomeric 1-O-hydroxyl group is free. This hemiacetal has been used successfully as an intermediate for glucosylation couplings, where it was converted into 2,3,4,6-tetra-O-benzyl-D-glucopyranose trichloroacetimidate using trichloroacetonitrile in the presence of a base such as potassium carbonate and DBU.
Importantly, this imidate donor with no neighbouring participating groups is commonly used for the selective formation of glucosides. 2,3,4,6-tetra-O-benzyl-D-glucopyranose can also be oxidized to the lactone, or reduced to give the open chain form.
Additionally, 2,3,4,6-tetra-O-benzyl-D-glucopyranose can be used for the preparation of glucono-1,5-lactone hydrazine, which was used, in-turn, to form a glucosylidene-spirocyclopropane.

Uses

It is the intermediate of Voglibose/Dapagliflozin. An important D-glucopyranose derivative for glucosylations and other reactions 1,2; Preparation of the α-glucopyranosyl chloride, synthesis of 1-C-α-D-glucopyranose derivatives.

Synthesis

Octa-O-Dissolves benzyl sucrose or octa-O-allyl sucrose in an organic solvent with the addition of hydrochloric acid without prior chromatographic purification, allows it to react for 20-60 minutes at temperatures of 50-60 °C. and then cleans the end product formed by crystallization. (ethanol, isopropanol, acetone, benzene, toluene or mixtures thereof can be used as solvents).

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE synthesis

Synthesis of 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE from β-D-Glucopyranoside, 4-methylphenyl 2,3,4,6-tetrakis-O-(phenylmethyl)-1-thio-

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Preparation Products And Raw materials

Raw materials

Preparation Products

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE Suppliers

Global( 290)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Jinli Pharmaceutical Co.,Ltd	+86-21-57256005 +86-15921811235	chang@shjlchem.com	China	20	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jinan Samuel Pharmaceutical CO., Ltd	0531-88821801 15192360884	605818151@qq.com	CHINA	124	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58

Supplier	Advantage
Shanghai Jinli Pharmaceutical Co.,Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
Hefei TNJ Chemical Industry Co.,Ltd.	55
career henan chemical co	58
Jinan Samuel Pharmaceutical CO., Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58

2,3,4, 6-Tetra-o-benzyl-α-D-Glucopyranose method for preparing partial benzylated aldopyranose
It is capable of synthesising some of the benzylated aldopyranose. And the method has good availability and low cost.
Nov 17，2023

View Lastest Price from 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-24	2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE 6564-72-3	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2021-11-02	2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE 6564-72-3	US $250.00 / KG	1KG	99%	100KGS	Baoji Guokang Healthchem co.,ltd
2021-09-29	2,3,4,6-tetra-O-benzyl-D-glucopyranose 6564-72-3	US $0.00 / g	10g	98.0%	500kg/month	WUHAN FORTUNA CHEMICAL CO., LTD

2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE
6564-72-3
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE
6564-72-3
US $250.00 / KG
99%
Baoji Guokang Healthchem co.,ltd

2,3,4,6-tetra-O-benzyl-D-glucopyranose
6564-72-3
US $0.00 / g
98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

6564-72-3(2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE)Related Search:

(S)-Valiolamine Voglibose Valiolamine (2S,3S,4S,5S)-5-Hydroxy-2,3,4-tris(phenylMethoxy)-5-[(phenylMethoxy)Methyl]-cyclohexanone (R)-Valiolamine Voglibose ETHYL 2,3,4,6-TETRA-O-ACETYL-ALPHA-D-THIOGLUCOPYRANOSIDE

Methyl-2,3,5-tri-O-benzoyl-alpha-D-arabinofuranoside 2,3,4,6-TETRA-O-ACETYL-ALPHA-D-MANNOPYRANOSYL AZIDE Methyl beta-D-ribofuranoside 2,3,4,6-TETRA-O-ACETYL-BETA-D-GLUCOPYRANOSYL ISOTHIOCYANATE 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl azide 3,4,6-Triacetate

FMOC-SER(GALNAC(AC)3-ALPHA-D)-OH Penta-O-benzoyl-alpha-D-mannopyranose 2-Deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-α-D-glucopyranosyl azide 3,4,6-Triacetate FMOC-THR(GALNAC(AC)3-ALPHA-D)-OH D-Galactose

2,3,4,6-Tetra-O-acetyl-alpha-D-glucopyranosyl bromide 2,3,4,6-Tetra-O-acetyl-alpha-D-galactopyranosyl bromide 2,3,4,6-Tetra-O-benzyl-D-glucopyranose

1of4

2,3,4,6-Tetra-O-benzyl-alpha-D-glucose (for Voglibose) 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSIDE 2,3,4,6-TETRA-O-BENZOYL-D-GLUCOPYRANOSE 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose benzylglucopyranose 6-Tetra-O-benzyl-D-glucopyranose 2,3,4,6-tetra-o-benzyl-d-glucose 2,3,4,6-Tetra-o-benzyl-D-glucopyransoe 2,3,4,6-Tetra-O-benzyl-a-D-glucopyranose 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE ,GB 2,3,4,6-TETRA-O-ACETYL A-D-GLUCOPYRANOSIDE 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranos alpha-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylMethyl)- a-D-Glucopyranose,2,3,4,6-tetrakis-O-(phenylMethyl)- Voglibose TBG IMpurity (2S,3R,4S,5R,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)Methyl)tetrahydro-2H-pyran-2-ol 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose SynonyMs 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose 2,3,4,6-Tetra-O-benzyl-alpha-D-glucose 2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranose Voglibose int Voglibose Impurity 1 2,3,4,6-Tetra-O-benzyl-D-glycopyranose Voglibose TBG impurities Voglibose alpha-TBG Impurity 2,3,4,6-Tetra-O-benzyl-α-D-glucopyranose 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOSE 6564-72-3 2,3,4,6-TETRA-O-BENZYL-D-GLUCOPYRANOSE USP/EP/BP 2,3,4,6-TETRA-O-BENZYL-ALPHA GLUCOPYRANOSE（COM） 2,3,4,6-TETRA-O-BENZYL-D-GLUCChemicalbookOPYRANOSE 2,3,4,6-Tetra-O-benzyl-D-glucopyranose(TBG) 2,3,4,6-Tetrakis-O-(phenylmethyl)-α-D-glucopyranose α-D-Glucopyranose, 2,3,4,6-tetrakis-O-(phenylmethyl)- Tetrabenzyl glucose 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSE 6564-72-3 Specialty Synthesis Monosaccharides Monosaccharide O-Substituted Sugars Sugars Carbohydrate Synthesis Carbohydrates Biochemicals and Reagents BioChemical Pharmaceutical Intermediates 6564-72-3