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4-amino-2-fluoro-N-methylbenzamide

4-amino-2-fluoro-N-methylbenzamide structure

CAS No.: 915087-25-1

Chemical Name:: 4-amino-2-fluoro-N-methylbenzamide

Synonyms: N-Methyl-2-fluoro-4-aminobenzamide;N-Methyl-4-amino-2-fluoro-benzamide;Enzalutamide ITS-3;Enzalutamide Impurity 20;Enzalutamide Impurity 40;4-AMINO-2-FLUORO-N-METHYLBENZAMIDE;4-amino-2-fluoro-N-menthylbenzamide;N-Methyl-2-fluoro-4-AminobenzoylAmine;2. 4-aMino-2-fluoro-N-MethylbenzaMide;BenzaMide, 4-aMino-2-fluoro-N-Methyl-

CBNumber:: CB02452656

Molecular Formula:: C8H9FN2O

Molecular Weight:: 168.17

MDL Number:: MFCD09909322

MOL File:: 915087-25-1.mol

MSDS File:: SDS

Last updated:2023-09-22 15:26:39

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4-amino-2-fluoro-N-methylbenzamide Properties

Melting point	160 - 163°C
Boiling point	320℃
Density	1.234
Flash point	147℃
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	14.12±0.46(Predicted)
color	White to Off-White
Stability	Moisture Sensitive
InChI	InChI=1S/C8H9FN2O/c1-11-8(12)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3,(H,11,12)
InChIKey	XOKAXPQJUODMSH-UHFFFAOYSA-N
SMILES	C(NC)(=O)C1=CC=C(N)C=C1F
FDA UNII	Y2H4HB3FQL

SAFETY

Risk and Safety Statements

Signal word	Warning
Hazard statements	H317-H319-H302
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
HS Code	2924297099

4-amino-2-fluoro-N-methylbenzamide price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A609743	4-Amino-2-fluoro-N-methylbenzamide	915087-25-1	25g	$275	2021-12-16	Buy
TRC	A609743	4-Amino-2-fluoro-N-methylbenzamide	915087-25-1	50g	$520	2021-12-16	Buy
AK Scientific	J95296	4-Amino-2-fluoro-N-methylbenzamide	915087-25-1	100g	$520	2021-12-16	Buy
Matrix Scientific	143913	4-Amino-2-fluoro-N-methylbenzamide 95%	915087-25-1	25g	$1110	2021-12-16	Buy
Matrix Scientific	143913	4-Amino-2-fluoro-N-methylbenzamide 95%	915087-25-1	5g	$370	2021-12-16	Buy

Product number	Packaging	Price	Buy
A609743	25g	$275	Buy
A609743	50g	$520	Buy
J95296	100g	$520	Buy
143913	25g	$1110	Buy
143913	5g	$370	Buy

4-amino-2-fluoro-N-methylbenzamide Chemical Properties,Uses,Production

Uses

4-amino-2-fluoro-N-methylbenzamide acts as a reagent in the design, synthesis and biological evaluation of novel 5-oxo-2-thioxoimidazolidine derivatives as potent androgen receptor antagonists. Also, in the preparation and structure-activity relationship of chiral benzyloxypyridinone derivatives as c-Met kinase inhibitors.

Description

4-amino-2-fluoro-N-methylbenzamide is a novel antiandrogen drug MDV (Marek's Disease Virus) 3100 key intermediate which is the new generation oral androgen antagonist medicine of united states drug developer Medivation company exploitation, be mainly used in treating advanced prostate cancer (CRPC) patient.

Preparation

2-fluoro-4-nitrotoluene as raw material, through potassium permanganate oxidation, the thionyl chloride chlorination, methylamine amination, and Pd/C hydrogenation reduction prepare 4-amino-2-fluoro-N-methylbenzamide.

4-amino-2-fluoro-N-methylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-(1-CYANOCYCLOBUTYLAMINO)-2-FLUORO-N-METHYLBENZAMIDE 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE

4-amino-2-fluoro-N-methylbenzamide Suppliers

Global( 222)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Porton Pharma Solutions Ltd.			China	56	58
Shanghai Joiny Pharmaceutical Co.,LTD	+8613681955282	gyd@joiny-pharma.com	China	228	58
Shandong Huisheng Import & Export Co., Ltd.	+86-13176845580 +86-13176845580	da@zhongda-biotech.com	China	248	58
Anhui Zhongda Biotechnology Co., Ltd	+8615689548120	linda@zhongda-biotech.com	China	204	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shandonghaohong biotechnology Co.,ltd.	0635-6175299 13961496334	sale@inyelchem.com	CHINA	44	55

Supplier	Advantage
Porton Pharma Solutions Ltd.	58
Shanghai Joiny Pharmaceutical Co.,LTD	58
Shandong Huisheng Import & Export Co., Ltd.	58
Anhui Zhongda Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shandonghaohong biotechnology Co.,ltd.	55

View Lastest Price from 4-amino-2-fluoro-N-methylbenzamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-24	4-AMINO-2-FLUORO-N-METHYLBENZAMIDE 915087-25-1	US $9.90-454.00 / g	1g	99%	100kg	Wuhan Cell Pharmaceutical Co., Ltd
2024-04-24	N-Methyl-2-fluoro-4-aminobenzamide 915087-25-1	US $15.00-50.00 / kg	1kg	NLT98%	5 ton per month	Anhui Dexinjia Biopharm Co., Ltd
2024-04-10	N-Methyl-2-fluoro-4-aminobenzamide 915087-25-1	US $0.00 / kg	1kg	98%	5500kg	Shanghai Joiny Pharmaceutical Co.,LTD

4-AMINO-2-FLUORO-N-METHYLBENZAMIDE
915087-25-1
US $9.90-454.00 / g
99%
Wuhan Cell Pharmaceutical Co., Ltd

N-Methyl-2-fluoro-4-aminobenzamide
915087-25-1
US $15.00-50.00 / kg
NLT98%
Anhui Dexinjia Biopharm Co., Ltd

N-Methyl-2-fluoro-4-aminobenzamide
915087-25-1
US $0.00 / kg
98%
Shanghai Joiny Pharmaceutical Co.,LTD

915087-25-1(4-amino-2-fluoro-N-methylbenzamide)Related Search:

4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE 2-FLUORO-N-METHYL-4-NITROBENZAMIDE Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile Enzalutamide Impurity 7

4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- [2H6]-Enzalutamide N-desMethyl EnzalutaMide Enzalutamide carboxylic acid Methyl 4-bromo-2-fluorobenzoate

Enzalutamide 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide 4-Bromo-2-fluorobenzoic acid methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate

EnzalutaMide IMpurity Enzalutamide 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester

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4-AMINO-2-FLUORO-N-METHYLBENZAMIDE BenzaMide, 4-aMino-2-fluoro-N-Methyl- 2. 4-aMino-2-fluoro-N-MethylbenzaMide 4-amino-2-fluoro-N-menthylbenzamide Enzalutamide Impurity 20 N-Methyl-2-fluoro-4-aminobenzamide N-Methyl-4-amino-2-fluoro-benzamide Enzalutamide ITS-3 N-Methyl-2-fluoro-4-AminobenzoylAmine Enzalutamide Impurity 40 915087-25-1 915087-25-1