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1-OCTADECYL LPA

1-OCTADECYL LPA Structure
1-OCTADECYL LPA structure
CAS No.
52977-29-4
Chemical Name:
1-OCTADECYL LPA
Synonyms
1-OCTADECYL LPA;1-OCTADECYL LYSOPHOSPHATIDIC ACID;1-Octadecyl Lysophosphatidic Acid Exclusive;1-Octadecyl Lysophosphatidic Acid (1-Octadecyl LPA);1,2-Propanediol, 3-(octadecyloxy)-, 1-(dihydrogen phosphate)
CBNumber:
CB02455642
Molecular Formula:
C21H45O6P
Molecular Weight:
424.55
MDL Number:
MFCD11045839
MOL File:
52977-29-4.mol
Last updated:2023-05-21 10:59:17
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1-OCTADECYL LPA Properties

storage temp. Store at -20°C
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) ((1:1): 0.5 mg/ml
form A crystalline solid

1-OCTADECYL LPA price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10010164 1-Octadecyl Lysophosphatidic Acid ≥95% 52977-29-4 500μg $26 2024-03-01 Buy
Cayman Chemical 10010164 1-Octadecyl Lysophosphatidic Acid ≥95% 52977-29-4 1mg $49 2024-03-01 Buy
Cayman Chemical 10010164 1-Octadecyl Lysophosphatidic Acid ≥95% 52977-29-4 5mg $192 2024-03-01 Buy
Cayman Chemical 10010164 1-Octadecyl Lysophosphatidic Acid ≥95% 52977-29-4 10mg $332 2024-03-01 Buy
AK Scientific 1374AH 3-(Octadecyloxy)-1-(dihydrogenphosphate)-1,2-propanediol 52977-29-4 10mg $440 2021-12-16 Buy
Product number Packaging Price Buy
10010164 500μg $26 Buy
10010164 1mg $49 Buy
10010164 5mg $192 Buy
10010164 10mg $332 Buy
1374AH 10mg $440 Buy

1-OCTADECYL LPA Chemical Properties,Uses,Production

Description

1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.3

References

1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family J. Biol. Chem. 278(28),25600-25606(2003).
2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions Trends Cell Biol. 4(6),213-219(1994).
3. Tokumura, A., Sinomiya, J., Kishimoto, S., et al. Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids Biochem. J. 365,617-628(2002).

1-OCTADECYL LPA Preparation Products And Raw materials

Raw materials

Preparation Products

1-OCTADECYL LPA Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29803 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Supplier Advantage
BOC Sciences 65
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Shanghai Maclean Biochemical Technology Co., LTD 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

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1-OCTADECYL LPA 1-OCTADECYL LYSOPHOSPHATIDIC ACID 1-Octadecyl Lysophosphatidic Acid Exclusive 1,2-Propanediol, 3-(octadecyloxy)-, 1-(dihydrogen phosphate) 1-Octadecyl Lysophosphatidic Acid (1-Octadecyl LPA) 52977-29-4