ChemicalBook >> CAS DataBase List >>COMPOUND 401
COMPOUND 401
- CAS No.
- 168425-64-7
- Chemical Name:
- COMPOUND 401
- Synonyms
- CS-315;Morpholino a;Compound 401, >=98%;COMPOUND401;COMPOUND-401;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one;2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one>2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one;4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-;2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
- CBNumber:
- CB02458229
- Molecular Formula:
- C16H15N3O2
- Molecular Weight:
- 281.31
- MDL Number:
- MFCD10568147
- MOL File:
- 168425-64-7.mol
- MSDS File:
- SDS
Last updated:2023-06-08 17:06:34
| Melting point | 184-186℃ (ethanol ) |
|---|---|
| Boiling point | 456.9±55.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3 (20 ºC 760 Torr) |
| storage temp. | Store at RT |
| solubility | DMSO : 6 mg/mL (21.33 mM; Need ultrasonic and warming) |
| pka | 1.01±0.20(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| CAS DataBase Reference | 168425-64-7 |
| FDA UNII | TN9PWB4UM5 |
COMPOUND 401 price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M2537 | 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one >98.0%(GC) | 168425-64-7 | 10mg | $83 | 2024-03-01 | Buy |
| TCI Chemical | M2537 | 2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one >98.0%(GC) | 168425-64-7 | 50mg | $292 | 2024-03-01 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 168425-64-7 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 168425-64-7 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 21769 | Compound 401 | 168425-64-7 | 10mg | $153 | 2024-03-01 | Buy |
COMPOUND 401 Chemical Properties,Uses,Production
Uses
Compound 401 is a selective inhibitor of DNA-PK and FRAP.
Biological Activity
Reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) (IC 50 values are 0.28 and 5.3 μ M respectively). Displays little affinity for other commonly studied kinases including PI 3-K, ATM and ATR (IC 50 values are all > 100 μ M). Induces apoptosis in vitro .
COMPOUND 401 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 74)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
168425-64-7(COMPOUND 401)Related Search:
2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one
4H-PyriMido[2,1-a]isoquinolin-4-one, 2-(4-Morpholinyl)-
2-(Morpholin-4-yl)pyrimido[2,1-a]isoquinolin-4-one
2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
Compound 401, >=98%
2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one
CS-315
COMPOUND401;COMPOUND-401
2-Morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one>
Morpholino a
DNA-PK,Compound401,DNA-dependent protein kinase,Compound-401,Compound 401,inhibit,Inhibitor
168425-64-7