CAY10580
- CAS No.
- 64054-40-6
- Chemical Name:
- CAY10580
- Synonyms
- CAY10580;CAY10580 Exclusive;CBWGHEDGUILASE-UHFFFAOYSA-N;2-(3-HYDROXYOCTYL)-5-OXO-1-PYRROLIDINEHEPTANOIC ACID;1-Pyrrolidineheptanoic acid, 2-(3-hydroxyoctyl)-5-oxo-
- CBNumber:
- CB02467917
- Molecular Formula:
- C19H35NO4
- Molecular Weight:
- 341.49
- MDL Number:
- MFCD11976917
- MOL File:
- 64054-40-6.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
CAY10580 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16835 | CAY10580 ≥96% | 64054-40-6 | 500μg | $71 | 2024-03-01 | Buy |
| Cayman Chemical | 16835 | CAY10580 ≥96% | 64054-40-6 | 1mg | $133 | 2024-03-01 | Buy |
| Cayman Chemical | 16835 | CAY10580 ≥96% | 64054-40-6 | 5mg | $554 | 2024-03-01 | Buy |
| Cayman Chemical | 16835 | CAY10580 ≥96% | 64054-40-6 | 10mg | $968 | 2024-03-01 | Buy |
| TRC | H953508 | 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoicacid | 64054-40-6 | 1000μg | $160 | 2021-12-16 | Buy |
CAY10580 Chemical Properties,Uses,Production
Uses
2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid is an analog of PGE2.
Uses
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It selectively binds the EP4 receptor (Ki = 35 nM) relative to the EP1, EP2, and EP3 receptors (Ki = 3,000, 2,000, and >3,000 nM, respectively). CAY10580 stimulates cAMP formation in excised mouse ovaries.[Cayman Chemical]
Definition
ChEBI: 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid is a pyrrolidin-2-one substituted by 6-carboxyhexyl and 3-hydroxyoctyl groups at positions 1 and 2, respectively. It is a potent prostaglandin EP4 receptor agonist (Ki=35 nM). It has a role as a prostaglandin receptor agonist. It is a member of pyrrolidin-2-ones, a hydroxy monocarboxylic acid and a secondary alcohol.
CAY10580 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
| Shanghai Tachizaki Biomedical Research Center | 18014399201 | sales@chemlab-tachizaki.com | China | 2490 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4164 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48467 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.com | China | 24246 | 58 |