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2-[2-(2-Azidoethoxy)ethoxy]ethanamine

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Structure
2-[2-(2-Azidoethoxy)ethoxy]ethanamine structure
CAS No.
166388-57-4
Chemical Name:
2-[2-(2-Azidoethoxy)ethoxy]ethanamine
Synonyms
N3-PEG2-NH2;Azido-PEG2-NH2;H2N-C2-PEG2-N3;Azide-PEG3-Amine;Azido-PEG2-Amine;N3-PEG2-CH2CH2NH2;Azido-PEG2-C2-amine;Azido-PEG2-CH2CH2NH2;Azido-PEG2-CH2CH2-Amine;Amino-PEG2-azide,NH2-PEG2-N3
CBNumber:
CB02484811
Molecular Formula:
C6H14N4O2
Molecular Weight:
174.2
MDL Number:
MFCD13189985
MOL File:
166388-57-4.mol
Last updated:2024-03-25 07:34:14
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2-[2-(2-Azidoethoxy)ethoxy]ethanamine Properties

solubility Soluble in Water, DMSO, DMF, DCM
form Liquid
CAS DataBase Reference 166388-57-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280
HS Code  2929900090

2-[2-(2-Azidoethoxy)ethoxy]ethanamine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B407568 2-[2-(2-Azidoethoxy)ethoxy]ethanamine 166388-57-4 1g $185 2021-12-16 Buy
Biosynth Carbosynth FP73033 Azido-PEG2-amine 166388-57-4 1g $200 2021-12-16 Buy
BroadPharm BP-20692 Azido-PEG2-amine 98% 166388-57-4 5G $295 2021-12-16 Buy
Biosynth Carbosynth FP73033 Azido-PEG2-amine 166388-57-4 2g $300 2021-12-16 Buy
ChemScene CS-0114352 Azido-PEG2-C2-amine 166388-57-4 5g $395 2021-12-16 Buy
Product number Packaging Price Buy
B407568 1g $185 Buy
FP73033 1g $200 Buy
BP-20692 5G $295 Buy
FP73033 2g $300 Buy
CS-0114352 5g $395 Buy

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Chemical Properties,Uses,Production

Description

Azido-PEG2-amine is a bifunctional crosslinker containing an amino and an azide group. The amino group is reactive with carboxylic acids, activated NHS esters,. The azide(N3) group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.

Synthesis

2-[2-(2-Hydroxyethoxy)ethoxy]ethyl chloride (15 g, 88.9 mmol), NaI(4.06 g, 27.1 mmol), and NaN3 (45.3 mg, 697 mmol) were dissolved in distilled water (90 mL), and the solution was stirred for 48 h at 50 °C. The reaction mixture extracted with ethyl acetate for three times. The organic layer was dried over Na2SO4 , and evaporated to collect 2-[2-(2-azidoethoxy)ethoxy]ethanol (14.0 g, 90.1%) as a yellow oil.To the solution 2-[2-(2-azidoethoxy)ethoxy]ethanol (8 g, 45.7 mmol) in THF (22.4 mL), 6 M NaOH(20.8 mL) and TsCl (13.1 g, 68.6 mmol) were added at 0 °C. The reaction mixture was stirred for 1 h at room temperature under nitrogen atmosphere. The solution was then extracted with diethyl ether four times, and the organic layer was washed with 1 M NaOH. After evaporation of the organic layer,2-[2-(2-azidoethoxy)ethoxy]ethyl tosylate (16.8 g, 98.6%) was obtained as a yellow oil.Finally, ammonia solution (28%, 14.8 mL, 365 mol) was added to the 2-[2-(2-azidoethoxy)ethoxy]-ethyl tosylate (8 g, 24.3 mmol) dissolved in THF (95.9 mL), and reaction mixture was stirred for 96 h at 40 °C. After the reaction, distilled water (50 mL) was added to the solution. The mixture was washed with diethyl ether and then extracted with dichloromethane. The organic layer was dried over NaSO4 and evaporated to obtain 2-[2-(2-azidoethoxy)ethoxy]ethanamine (2.49 g, 58.8%) as a yellow oil.
synthesis of 2-[2-(2-Azidoethoxy)ethoxy]ethanamine

2-[2-(2-Azidoethoxy)ethoxy]ethanamine synthesis

929-59-9
166388-57-4
Synthesis of 2-[2-(2-Azidoethoxy)ethoxy]ethanamine from 1,8-Diamino-3,6-dioxaoctane

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Preparation Products And Raw materials

Raw materials

Ethanamine, 2-[2-(2-bromoethoxy)ethoxy]- Boc-1-amino-3,6-dioxa-8-octanediamine 1,8-Diamino-3,6-dioxaoctane Ethane, 1,2-bis(2-bromoethoxy)- t-Boc-N-Amido-PEG2-Azide
(2-[2-(2-HYDROXY-ETHOXY)-ETHOXY]-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER Triethylene Glycol Dimethanesulfonate Tri(Ethylene Glycol) DI-P-Toluenesulfonate 1,8-Diazido-3,5-dioxaoctane 1,2-Bis(2-chloroethoxy)ethane
Triethylene glycol

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Preparation Products

2-[2-(2-Azidoethoxy)ethoxy]ethanamine Suppliers

Global( 103)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 12468 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Borenpharm Co., Ltd 		027-65563561 18717150066 3207347307@qq.com CHINA 1238 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4022 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Accela ChemBio Inc. 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
TargetMol Chemicals Inc. 		58
Wuhan Borenpharm Co., Ltd 		58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		58
Nextpeptide Inc 		58

Related articles

View Lastest Price from 2-[2-(2-Azidoethoxy)ethoxy]ethanamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
azido-PEG2-amine pictures 2024-03-24 azido-PEG2-amine
166388-57-4
 US $0.00 / g 10g >98.00% 10g Xian confluore Biological Technology Co., Ltd.
  • azido-PEG2-amine pictures
  • azido-PEG2-amine
    166388-57-4
  • US $0.00 / g
  • >98.00%
  • Xian confluore Biological Technology Co., Ltd.

166388-57-4(2-[2-(2-Azidoethoxy)ethoxy]ethanamine)Related Search:

2-(2-Azidoethoxy)ethanol Biotin-PEG3-propionic acid HS-PEG4-tBu 5,8,11,14-Tetraoxa-2-azahexadecanoic acid,16-amino-,1,1-dimethyl ester 3,6,9,12-tetraoxatridecylamine
PENTAETHYLENE GLYCOL H2N-PEG4-tBu 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Decaethylene glycol O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL
6-Maleimidocaproic acid 2-[2-(2-methoxyethoxy)ethoxy]-ethanethiol 2,5,8,11,14,17,20,23-Octaoxapentacosane-25-thiol HEPTAETHYLENE GLYCOL FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
MPEG7-CH2CH2COOH (R)-N-(3,6,9,12-Tetraoxatridecyl)-alpha-lipoamide Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid

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N3-PEG2-CH2CH2NH2 Azido-PEG2-Amine 2-[2-(2-Azidoethoxy)ethoxy]ethanamine N3-PEG2-NH2 Azido-PEG2-NH2 2-[2-(2-Azido-ethoxy)-ethoxy]-ethylamine Azido-PEG2-C2-amine Amino-PEG2-azide,NH2-PEG2-N3 Azide-PEG3-Amine Ethanamine, 2-[2-(2-azidoethoxy)ethoxy]- N3-PEG2-CH2CH2NH2/Ethanamine, 2-[2-(2-azidoethoxy)ethoxy]- H2N-C2-PEG2-N3 Azido-PEG2-CH2CH2NH2 Azido-PEG2-CH2CH2-Amine 166388-57-4 1660388-57-4 peg