ChemicalBook >> CAS DataBase List >>5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate structure

CAS No.: 239463-85-5

Chemical Name:: 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate

Synonyms: Silodosin Impurity 9;Silodosin inetermediate;Silodosin KSM-1;3-dihydroxybutanedioate;Silodosin Intermediates;Silodoxin intermediate b;Silodosin parent nucleus;3-dihydro-1H-indole-7-carbonitrile (2R;5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2;3-[5-[(2R)-2-Aminopropyl]-7-cyano-indolin-1-yl]propyl benzoate

CBNumber:: CB02485070

Molecular Formula:: C26H31N3O8

Molecular Weight:: 513.55

MDL Number:: MFCD16038449

MOL File:: 239463-85-5.mol

MSDS File:: SDS

Last updated:2023-09-04 15:51:00

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5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Properties

Melting point	> 180° C (dec.)
storage temp.	Inert atmosphere,Room Temperature
solubility	DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli
form	Solid
color	Off-White to Pale Yellow
Stability	Hygroscopic
InChIKey	KYUCVOVGODORNE-FRUDENECNA-N
SMILES	[C@H](O)(C(=O)O)[C@@H](O)C(=O)O.C(N1CCC2C=C(C[C@H](N)C)C=C(C#N)C1=2)CCOC(C1C=CC=CC=1)=O \|&1:0,5,18,r\|
CAS DataBase Reference	239463-85-5

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A628255	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile(2R,3R)-2,3-Dihydroxybutanedioate	239463-85-5	10g	$1240	2021-12-16	Buy
American Custom Chemicals Corporation	CCH0000401	5-[(2R)-2-AMINOPROPYL]-1-[3-(BENZOYLOXY)PROPYL]-2,3-DIHYDRO-1H-INDOLE-7-CARBONITRILE (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE 95.00%	239463-85-5	10G	$1334.03	2021-12-16	Buy
Biosynth Carbosynth	FA43183	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate	239463-85-5	10g	$450	2021-12-16	Buy
AK Scientific	X6203	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-Indole-7-carbonitrile-(2R,3R)-2,3-dihydroxybutanedioate	239463-85-5	5g	$451	2021-12-16	Buy
Biosynth Carbosynth	FA43183	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate	239463-85-5	25g	$750	2021-12-16	Buy

Product number	Packaging	Price	Buy
A628255	10g	$1240	Buy
CCH0000401	10G	$1334.03	Buy
FA43183	10g	$450	Buy
X6203	5g	$451	Buy
FA43183	25g	$750	Buy

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Chemical Properties,Uses,Production

Uses

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-Dihydroxybutanedioate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy.

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate synthesis

Synthesis of 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate from 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Preparation Products And Raw materials

Raw materials

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole

Preparation Products

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Suppliers

Global( 240)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd	+86-010-83386758 +86-18810831598	jennifer@lianben.com	China	85	58
Jiangsu Yutian pharmaceutical Co.,Ltd.	+undefined-0518-86098006 +undefined19851887368	lvan.hui@jsytsw.com	China	80	58
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.	+86-18616643091 +86-18616643091	info@rochipharma.com	China	246	58
Shanghai Joiny Pharmaceutical Co.,LTD	+8613681955282	gyd@joiny-pharma.com	China	228	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
NINGBO INNO PHARMCHEM CO., LTD.	13867897135	sales@nbinno.com	CHINA	925	58

Supplier	Advantage
Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd	58
Jiangsu Yutian pharmaceutical Co.,Ltd.	58
Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.	58
Shanghai Joiny Pharmaceutical Co.,LTD	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
NINGBO INNO PHARMCHEM CO., LTD.	58

View Lastest Price from 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-10	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate 239463-85-5	US $0.00 / kg	1kg	98%	500kg	Shanghai Joiny Pharmaceutical Co.,LTD
2024-04-10	Silodosin Intermediates 239463-85-5	US $0.00 / Kg/Bag	2Kg/Bag	99% up, High Density	20 tons	Sinoway Industrial co., ltd.
2022-09-30	5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate 239463-85-5	US $30.00-28.00 / Kg	1Kg	99.0% up	50 tons per month	Xinxiang Hongqi District Houyuan Trading Co.,Ltd

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate
239463-85-5
US $0.00 / kg
98%
Shanghai Joiny Pharmaceutical Co.,LTD

Silodosin Intermediates
239463-85-5
US $0.00 / Kg/Bag
99% up, High Density
Sinoway Industrial co., ltd.

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate
239463-85-5
US $30.00-28.00 / Kg
99.0% up
Xinxiang Hongqi District Houyuan Trading Co.,Ltd

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate Spectrum

5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate(239463-85-5)¹HNMR

239463-85-5(5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate)Related Search:

Silodosin Impurity 26 PSI-6130 derivative Pyrazine-2,5-dicarboxylic acid (1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol ((2R,3R,4R)-3-(benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl)methyl benzoate

(R)-(+)-1-(1-Naphthyl)ethylamine Pregabalin 5-Fluoro-2-nitroanisole 5-Aminolevulinic acid hydrochloride Clopidogrel hydrogen sulfate

Ethyl (3R)-piperidine-3-carboxylate 4-Hydroxypiperidine (Z)-3-(3-chloropropyl)-7,8-diethyl-1H-benzo[d] azepin-2 (3H)-one 4,5-Dimethoxy-1-cyanobenzocyclobutane (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

Donepezil 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate (R,R)-1,2-bis(methanesulfonyloxymethyl)cyclohexane

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5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate (1:1) R)-5-(2-aMinopropyl)-1-(3-benzyloxypropyl) indoline-7-carbonitrile tartrate (R)-3-(5-(2-aMinopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate 5-[(2R)-2-AMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioa 5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole(2R,3R)-2,3-dihydroxybutanedioat 5-((2R)-2-AMINOPROPLY)-1-(3-(BENZYLOXY)PROPYL)-2,3-DIHYDRO-7-CARBONOTRILE-1H-INDOLE-(2R,3R)-2,3-DIHYDROBUTANEDIOATE (ACI 5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile -1H-indole (2R,3R)-2,3-dihydroxybutanedioate 5-[(2R)-2-AMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dih 5-[(2R)-2-aMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-Indole-7-carbonitrile tartarate 5-[(2R)-2-AMinopropyl]-1-[3-(benzoyloxy)propyl] -2,3-dihydro-1H-indole-7-carbonitrile 5-[(2R)-2-AMinopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H- 3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate (R)-5-(2-aminopropyl)-1-(3-benzyloxypropyl) indoline-7-carbonitrile tartaric acid 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole (2R,3R)-2,3-dihydroxybutanedioate (1:1) 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioat 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2, 3-dihydroxybutanedioate(for Silodoxin) 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate###239463-85-5 3-[5-[(2R)-2-Aminopropyl]-7-cyano-indolin-1-yl]propyl benzoate (R)-5-(2-aminopropyl)-1-(3-benzoyloxypropyl) Indoline-7-Carbonitrile Tartaric acid 5_[(2R)-2-aminopropyl]-l-[3-(benzoyloxy)propyll-2,3-dihydro-7-carbonitrile 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile(2R,3R)-2,3-dihydroxybutanendioate 3-[5-[(2R)-2-aminopropyl]-7-cyano-2,3-dihydroindol-1-yl]propyl benzoate,(2R,3R)-2,3-dihydroxybutanedioic acid 3-dihydro-1H-indole-7-carbonitrile (2R 3-dihydroxybutanedioate 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2 Silodoxin intermediate b 5-[(2R)-2-AMINOPROPYL]-1-[3-(BENZOYLOXY)PROPYL]-2,3-DIHYDRO-1H-INDOLE-7-CARBO- 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate(For export only) 5-[(2R)-2-aminopropyl]-1-[3-(benzyloxy)propyl]-2,3-dihydro-7-carbonitrile-1H-indole(2R,3R)-2,3-dihydroxy butanedioate 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3- dihydro-1H- indole-7-carbonitrile (2R,3R)-2,3- Silodosin KSM-1 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-... 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7-carbonitrile (2R,3R) Silodosin inetermediate Silodosin Impurity 9 Silodosin Intermediates 3-(5-((R)-2-Aminopropyl)-7-Cyanoindolin-1-yl)propyl benzoate L-Tartrate 1H-Indole-7-carbonitrile, 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (9CI, ACI) 5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-Indole-7-carbonitrile (2R,3R)-2,3-dihydroxybutanedioate (1:1) (9CI ACI) 5[(2R)2Aminopropyl]1[3(benzoyloxy)propyl]2,3dihydro1Hindole7carbonitrile (2R,3R)2,3dihydroxybutanedioate,5 [(2R) 2 Aminopropyl] 1 [3 (benzoyloxy)propyl] 2,3 dihydro 1H indole 7 carbonitrile (2R,3R) 2,3 dihydroxybutanedioate 5-[(2R)-2-Aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-indole-7carbonitrile L-tartrate Silodosin parent nucleus 239463-85-5 239463-85-6 C22H25N3O2C4H6O6 C26H31N3O8 Intermediates