ChemicalBook >> CAS DataBase List >>PAC-1-d8
PAC-1-d8
- CAS No.
- 1287241-26-2
- Chemical Name:
- PAC-1-d8
- Synonyms
- PAC-1-d8;[2H8]-PAC-1;YQNRVGJCPCNMKT-SRNXAORYSA-N
- CBNumber:
- CB02511333
- Molecular Formula:
- C23H28N4O2
- Molecular Weight:
- 392.49402
- MDL Number:
- MOL File:
- 1287241-26-2.mol
Last updated:2023-05-15 10:43:35
PAC-1-d8 price More Price(2)
PAC-1-d8 Chemical Properties,Uses,Production
Uses
Labelled PAC-1 is a caspase 3 activator. Caspase activation is a key strategy in cancer therapy. Caspase 3 is a key executioner caspase and direct effector of apoptosis. Hallmark of many cancers is the circumvention of signal in the activation of executioner caspases and loss of apoptotic response. EC50 for caspase 3 activation = 0.33 μM and caspase 7= 4.5 μM. The IC50 for apoptosis induction = 0.92 μM. Elevated caspase 3 level in cancerous cell lines and tissues allows PAC-1 to selectively induce apoptosis in tissues.
PAC-1-d8 Preparation Products And Raw materials
Raw materials
Preparation Products
PAC-1-d8 Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55591 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
PAC-1-d8
YQNRVGJCPCNMKT-SRNXAORYSA-N
[2H8]-PAC-1
1287241-26-2
C23H20D8N4O2
Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Isotope Labelled Compounds
Pharmaceuticals