ChemicalBook
Chinese Japanese Germany

Fexofenadine hydrochloride

Description References
Fexofenadine hydrochloride
Fexofenadine hydrochloride
CAS No.
153439-40-8
Chemical Name:
Fexofenadine hydrochloride
Synonyms
Fexo;Allegra;Telfast;Alernex;Feksine;Fexofen;Fexadyne;Vivafeks;MDL 16455A;Telfast BD
CBNumber:
CB0256621
Molecular Formula:
C32H40ClNO4
Formula Weight:
538.12
MOL File:
153439-40-8.mol

Fexofenadine hydrochloride Properties

Melting point:
148-150oC
RTECS 
CY1633377
storage temp. 
−20°C
solubility 
Soluble in Dimethyl sulfoxide (50 mM), and methanol.
form 
powder
color 
white to beige
Merck 
14,4068
InChIKey
RRJFVPUCXDGFJB-UHFFFAOYSA-N
CAS DataBase Reference
153439-40-8(CAS DataBase Reference)

SAFETY

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

Fexofenadine hydrochloride price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F9427 Fexofenadine hydrochloride >98% (HPLC) 153439-40-8 10mg $143 2018-11-13 Buy
Sigma-Aldrich 1270377 Fexofenadine hydrochloride United States Pharmacopeia (USP) Reference Standard 153439-40-8 200mg $352.8 2018-11-13 Buy
TCI Chemical F0698 Fexofenadine Hydrochloride >98.0%(HPLC)(T) 153439-40-8 1g $48 2018-11-22 Buy
TCI Chemical F0698 Fexofenadine Hydrochloride >98.0%(HPLC)(T) 153439-40-8 5g $138 2018-11-22 Buy
Alfa Aesar J63262 Fexofenadine hydrochloride 153439-40-8 100mg $140 2018-11-13 Buy

Fexofenadine hydrochloride Chemical Properties,Uses,Production

Description

Fexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.

References

http://www.rxlist.com/allegra-drug/consumer-uses.htm
https://en.wikipedia.org/wiki/Fexofenadine

Chemical Properties

Off-White Crystalline Solid

Uses

A metabolite of of terfenadine, a H1-Histamine receptor antagonist

Uses

The active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.

Uses

Antihistaminic;histamine H1-receptor antagonist

Uses

Fexofenadine is a non-sedating antihistamine that selectively antagonizes the histamine H1 receptor with a Ki value of 10 nM and exhibits anti-inflammatory effects. It is devoid of central nervous system effects in part because it is a good substrate for the P-glycoprotein efflux pump situated within the blood-brain barrier.[Cayman Chemical]

Biological Activity

Selective histamine H 1 receptor antagonist (pK i = 8.1). Active metabolite of terfenadine that displays non-sedating antiallergic effects.牋.

Fexofenadine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Fexofenadine hydrochloride Suppliers

Global( 228)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19953 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1374 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2548 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 552 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1659 55
Hebei Huanhao Biotechnology Co., Ltd.
86-0311-83975816
86-0311-83975816 lisa@hbhuanhao.com CHINA 667 58

View Lastest Price from Fexofenadine hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-04-03 Fexofenadine hydrochloride
153439-40-8
US $10.00 / KG 10G 99% 10MT Hubei XinRunde Chemical Co., Ltd.
2018-09-18 Fexofenadine HCl
153439-40-8
US $120.00 / G 10G 99.8% 500kg/month Hebei Huanhao Biotechnology Co., Ltd.
2018-08-20 Fexofenadine hydrochloride
153439-40-8
US $1.00 / KG 1G 98% 100KG career henan chemical co

153439-40-8(Fexofenadine hydrochloride )Related Search:


  • α,α-dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]benzeneacetic acid
  • Benzeneacetic acid, 4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethyl-, hydrochloride
  • MDL 16455A
  • Telfast
  • Telfast BD
  • 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid hydrochloride
  • 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methyl-propanoic acid hydrochloride
  • Fexofenadine(Hclform)
  • 2-[4-[1-Hydroxy-4-[4-(hydroxy-diphenyl-methyl)-1-piperidyl]-butyl]phenyl]-2-methyl-propanoic acid hydrochloride
  • Allegra
  • Fexofenadine hydrochloride
  • FERULICACIDPIPERAZINE
  • (Carboxyterfenadine-D10,Terfenadinecarboxylate)
  • Fexofenidine hydrochloride, MDL 16455 hydrochloride, Terfenidine carboxylate hydrochloride
  • 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]-1-piperidyl]butyl]phenyl]-2-methyl-propionic acid hydrochloride
  • α,α-Dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-benzeneaceticacidhydrochloride
  • Fexofenadine hydrochloride,Fexofenidine hydrochloride, MDL 16455 hydrochloride, Terfenidine carboxylate hydrochloride
  • 2-{4-[(1R)-1-hydroxy-4-[4-(hydroxydiphenylMethyl)piperidin-1-yl]butyl]phenyl}-2-Methylpropanoic acid
  • 4-[1-Hydroxy-4-[4-(hydroxydiphenylMethyl)-1-piperidinyl]butyl]-α,α-diMethylbenzeneacetic Acid Hydrochloride
  • Alernex
  • Carboxyterfenadine Hydrochloride
  • Feksine
  • Fexadyne
  • Fexo
  • Fexofen
  • Terfenadinecarboxylate Hydrochloride
  • Vivafeks
  • (R)-2-(4-(1-hydroxy-4-(4-(hydroxydiphenylMethyl)piperidin-1-yl)butyl)phenyl)-2-Methylpropanoic acid hydrochloride
  • 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid h
  • Benzeneaceticacid, 4-[1-hydroxy-4-[4-(hydroxydiphenylMethyl)-1-piperidinyl]butyl]-a,a-diMethyl-,hydrochloride (1:1)
  • feofenadine hydrochloride
  • 2-(4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic aci
  • FEXOFENADINE-D10 HCL
  • Non - Determination of hydrochloride
  • 153439-40-8
  • C32H40ClNO4
  • Aromatics
  • Heterocycles
  • Metabolites & Impurities
  • API
  • Intermediates & Fine Chemicals
  • Metabolites
  • Pharmaceuticals
  • C32H29D10NO4HCl
  • C32H39NO4ClH
  • C32H39NO4xHCl
Copyright 2017 © ChemicalBook. All rights reserved