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TriMethyl(broModifluoroMethyl)silane

TriMethyl(broModifluoroMethyl)silane Structure
TriMethyl(broModifluoroMethyl)silane structure
CAS No.
115262-01-6
Chemical Name:
TriMethyl(broModifluoroMethyl)silane
Synonyms
(BroModifluoroMethyl)triMethylsilane;(Bromodifluoromethyl);Difluorobromomethylsilane;Bromodifluoro(trimethylsilyl)methane;TriMethyl(broModifluoroMethyl)silane;Silane, (bromodifluoromethyl)trimethyl-;(Bromodifluoromethyl)trimethylsilane >Trimethyl(bromodifluoromethyl)silane 97%;(Bromodifluoromethyl)trimethylsilane 98%;(Bromodifluoromethyl)trimethylsilane, 98+%
CBNumber:
CB02611493
Molecular Formula:
C4H9BrF2Si
Molecular Weight:
203.1
MDL Number:
MFCD18641931
MOL File:
115262-01-6.mol
MSDS File:
SDS
Last updated:2024-04-15 18:41:30
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TriMethyl(broModifluoroMethyl)silane Properties

Boiling point 108°C(lit.)
Density 1.306
refractive index n/D1.407
Flash point 46℃
storage temp. -20°C
form liquid
color clear
InChIKey WDZVWBWAUSUTTO-UHFFFAOYSA-N
CAS DataBase Reference 115262-01-6

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
Risk Statements  11
Safety Statements  24/25
RIDADR  UN 1993C 3 / PGIII
TSCA  No
HazardClass  3
PackingGroup  II
HS Code  29319090
NFPA 704
4
0 0

TriMethyl(broModifluoroMethyl)silane price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 808601 (Bromodifluoromethyl) 98% 115262-01-6 1g $118 2023-01-07 Buy
TCI Chemical B4325 (Bromodifluoromethyl)trimethylsilane >98.0%(GC) 115262-01-6 1g $93 2024-03-01 Buy
TCI Chemical B4325 (Bromodifluoromethyl)trimethylsilane >98.0%(GC) 115262-01-6 5g $281 2024-03-01 Buy
TRC T895825 Trimethyl(bromodifluoromethyl)silane 115262-01-6 100mg $60 2021-12-16 Buy
Biosynth Carbosynth FB60402 (Bromodifluoromethyl)trimethylsilane 115262-01-6 500mg $60 2021-12-16 Buy
Product number Packaging Price Buy
808601 1g $118 Buy
B4325 1g $93 Buy
B4325 5g $281 Buy
T895825 100mg $60 Buy
FB60402 500mg $60 Buy

TriMethyl(broModifluoroMethyl)silane Chemical Properties,Uses,Production

Uses

Novel difluorocarbene source for the efficient difluoromethylenation of alkenes/alkynes and difluoromethylation of O-, S-, and N-nucleophiles.

Uses

Trimethyl(bromodifluoromethyl)silane can be used as neuroactive steroids.

Uses

As reported by Hu and co-workers, (Bromodifluoromethyl)trimethylsilane is a highly useful reagent for the formation of difluoromethene-containing 3-membered rings and can also difluoromethylate heteroatoms with the assistance of alkaline bases, most effectively KOH.

Reactions

(1) Difluoromethylenation of TMSCN.
TriMethyl(broModifluoroMethyl)silane
Ref. J. Org. Chem. 2012, 77, 5850?5855.
(2) Difluoromethylenation of benzyl and alkylzinc halides.
TriMethyl(broModifluoroMethyl)silane
Ref. Org. Lett. 2013, 15, 917 – 919.
(3) Fluorination aminocarbonylation of aldehydes
TriMethyl(broModifluoroMethyl)silane
Ref. Angew. Chem. Int. Ed. 2022, e202115467

General Description

(Bromodifluoromethyl)trimethylsilane (TMSCF2Br) is commonly used as a source to generate dilfluorocarbene. TMSCF3 (Ruppert–Prakash reagent) and BBr3 undergoes fast halogen–exchange reaction to form MSCF2Br.

References

[1]Angewandte Chemie International Edition.DOI :10.1002/anie.202283811
[2]The Journal of Organic Chemistry.DOI :10.1021/acs.orglett.2c02899

TriMethyl(broModifluoroMethyl)silane synthesis

65864-64-4
115262-01-6
Synthesis of TriMethyl(broModifluoroMethyl)silane from (Difluoromethyl)trimethylsilane

TriMethyl(broModifluoroMethyl)silane Preparation Products And Raw materials

Raw materials

(chlorodifluoroMethyl)triMethylsilane DIBROMODIFLUOROMETHANE (Difluoromethyl)trimethylsilane Bromotrimethylsilane (Trifluoromethyl)trimethylsilane
Chlorotrimethylsilane

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Preparation Products

BROMODIFLUOROMETHANE (Difluoromethyl)trimethylsilane [(difluoromethyl)thio]benzene benzyl 2-(difluoromethoxy)acetate

TriMethyl(broModifluoroMethyl)silane Suppliers

Global( 127)Suppliers
Supplier Tel Email Country ProdList Advantage
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Changzhou Ditong Chemical Co.,Ltd 		+86-0519-88299272 info@edengenechem.com China 2169 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Allfluoro pharmaceutical co. ltd. 		021-26137118 +8615821363818 sales@allfluoro.com China 5791 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23556 58
Supplier Advantage
Zibo Hangyu Biotechnology Development Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
Accela ChemBio Inc. 		58
Changzhou Ditong Chemical Co.,Ltd 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
career henan chemical co 		58
Allfluoro pharmaceutical co. ltd. 		58
ANHUI WITOP BIOTECH CO., LTD 		58

View Lastest Price from TriMethyl(broModifluoroMethyl)silane manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TriMethyl(broModifluoroMethyl)silane pictures 2024-04-15 TriMethyl(broModifluoroMethyl)silane
115262-01-6
 US $0.10-0.10 / kg 0.004999999888241291kg 99.99% 20 tons Zibo Hangyu Biotechnology Development Co., Ltd
TriMethyl(broModifluoroMethyl)silane pictures 2022-10-10 TriMethyl(broModifluoroMethyl)silane
115262-01-6
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
(Bromodifluoromethyl)trimethylsilane pictures 2021-07-13 (Bromodifluoromethyl)trimethylsilane
115262-01-6
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

TriMethyl(broModifluoroMethyl)silane Spectrum

TriMethyl(broModifluoroMethyl)silane(115262-01-6)1HNMRTriMethyl(broModifluoroMethyl)silane(115262-01-6)FT-IR

115262-01-6(TriMethyl(broModifluoroMethyl)silane)Related Search:

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(Bromodifluoromethyl)trimethylsilane 98% TriMethyl(broModifluoroMethyl)silane Bromodifluoro(trimethylsilyl)methane (Bromodifluoromethyl) Trimethyl(bromodifluoromethyl)silane 97% (Bromodifluoromethyl)trimethylsilane > Silane, (bromodifluoromethyl)trimethyl- Difluorobromomethylsilane TriMethyl(broModifluoroMethyl)silane ISO 9001：2015 REACH (BroModifluoroMethyl)triMethylsilane (Bromodifluoromethyl)trimethylsilane, 98+% 115262-01-6 C4H9BrF2Si