ChemicalBook >> CAS DataBase List >>Regorafenib
Regorafenib
- CAS No.
- 835621-08-4
- Chemical Name:
- Regorafenib
- Synonyms
- Regorafenib mesylate;Regorafenib (methanesulfonate)
- CBNumber:
- CB02642550
- Molecular Formula:
- C22H19ClF4N4O6S
- Molecular Weight:
- 578.92
- MDL Number:
- MOL File:
- 835621-08-4.mol
Last updated:2023-08-02 17:35:45
Regorafenib Chemical Properties,Uses,Production
Uses
BAY 73-4506 (Regorafenib) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.
Definition
ChEBI: Regorafenib is a pyridinecarboxamide obtained by condensation of 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]pyridine-2-carboxylic acid with methylamine. Used for for the treatment of metastatic colorectal cancer in patients who have previously received chemotherapy, anti-EGFR or anti-VEGF therapy. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor and a hepatotoxic agent. It is an aromatic ether, a pyridinecarboxamide, a member of monochlorobenzenes, a member of (trifluoromethyl)benzenes, a member of monofluorobenzenes and a member of phenylureas.
Regorafenib Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 7)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
| Jinan Trio PharmaTech Co., Ltd. | +86 (531) 88811783 | sales@trio-pharmatech.com (International market) | China | 1856 | 62 |
| SYN|thesis med chem P/L | +86-021-50720296 | service@synkinase.com | China | 266 | 58 |
| Raw material medicin reagent co.,Ltd | 025-57798860 | sales@njromanme.com | China | 4534 | 58 |
| Wuhan FengyaoTonghui Chemical Products Co., Ltd. | 027-87466105 15377573527 | 2678564200@qq.com | China | 17997 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
View Lastest Price from Regorafenib manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-12 | Regorafenib
835621-08-4
|
US $0.00 / g | 1g | 98% HPLC | 1kg | shandong perfect biotechnology co.ltd |
-
- Regorafenib
835621-08-4
- US $0.00 / g
- 98% HPLC
- shandong perfect biotechnology co.ltd
Regorafenib (methanesulfonate)
Regorafenib mesylate
835621-08-4