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ChemicalBook >> CAS DataBase List >>N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Structure
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide structure
CAS No.
289472-81-7
Chemical Name:
N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
Synonyms
Bortezomib EP IMP M;Bortezomib USP IMP J;Bortezomib Impurity D;Bortezomib Impurity J;Bortezomib Impurity 48;Bortezomib USP Impurity J;BortezomibHydroxy(1S,2S)-Isomer;Bortezomib USP Related Compoud J;(S)-Hydroxy Des(boric Acid) BortezoMib;(S,S)-Bortezomib Hydroxyisopentyl Amide Analog
CBNumber:
CB02661665
Molecular Formula:
C19H24N4O3
Molecular Weight:
356.42
MDL Number:
MOL File:
289472-81-7.mol
Last updated:2023-05-15 10:43:55
Request For Quotation

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Properties

Boiling point 672.0±55.0 °C(Predicted)
Density 1.199±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka 11.90±0.46(Predicted)
form Solid
color White to Off-White
FDA UNII BGP3WC2T3P

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H935905 (S)-HydroxyDes(boricAcid)Bortezomib 289472-81-7 5mg $1455 2021-12-16 Buy
American Custom Chemicals Corporation CCH0032708 N-((S)-1-(((S)-1-HYDROXY-3-METHYLBUTYL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)PYRAZINE-2-CARBOXAMIDE 95.00% 289472-81-7 5MG $496.22 2021-12-16 Buy
American Custom Chemicals Corporation CCH0032708 N-((S)-1-(((S)-1-HYDROXY-3-METHYLBUTYL)AMINO)-1-OXO-3-PHENYLPROPAN-2-YL)PYRAZINE-2-CARBOXAMIDE 95.00% 289472-81-7 1G $1365 2021-12-16 Buy
Chemenu CM168043 N-((S)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide 95%+ 289472-81-7 1g $1365 2021-12-16 Buy
Crysdot CD11152974 N-((S)-1-(((S)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide 95+% 289472-81-7 1g $947 2021-12-16 Buy
Product number Packaging Price Buy
H935905 5mg $1455 Buy
CCH0032708 5MG $496.22 Buy
CCH0032708 1G $1365 Buy
CM168043 1g $1365 Buy
CD11152974 1g $947 Buy

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Chemical Properties,Uses,Production

Uses

(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Preparation Products And Raw materials

Raw materials

Preparation Products

N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide Suppliers

Global( 68)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
CR Corporation Lomited 		fred.wen@crcorporation.cn CHINA 12069 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24738 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Guangzhou PI PI Biotech Inc +86-020-81716320 +86-13602409664 Sales@pipitech.com China 3635 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Supplier Advantage
Standardpharm Co. Ltd. 		58
CR Corporation Lomited 		58
sgtlifesciences pvt ltd 		58
LEAP CHEM CO., LTD. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
China National Standard Pharmaceutical Corporation Limited 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Guangzhou PI PI Biotech Inc 55
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50

289472-81-7(N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide)Related Search:

2,3-Pyrazinedicarboxylic acid Bortezomib Impurity 35 Bortezomib Impurity 23 tert-Butyl Tosylate DISCONTINUED Bortezomib Impurity 5
1-Chloro-2-methylpropane Bortezomib Impurity 45 BOC-D-Phenylalanine bortezoMib iMpurity H Boronic acid, B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]butyl]-
2-PyrazinecarboxaMide, N-[(1S)-2-[[(1R)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide ((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid 2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- N-((S)-1-(((R)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide
((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxaMido)propanaMido)butyl)boronic acid Bortezomib Impurity 47 HCl 1-Bromo-2-methylpropane

1of4

2-PyrazinecarboxaMide, N-[(1S)-2-[[(1S)-1-hydroxy-3-Methylbutyl]aMino]-2-oxo-1-(phenylMethyl)ethyl]- (S)-Hydroxy Des(boric Acid) BortezoMib (N-[(1S)-1-hydroxy-3-Methylbutyl]-Nα-(pyrazin-2-ylcarbonyl)-L-phenylalaninaMide Bortezomib Impurity 48 Bortezomib Impurity J N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide Bortezomib USP IMP J Bortezomib Impurity D Bortezomib USP Related Compoud J N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazi Bortezomib USP Impurity J Bortezomib Related Compund J/ (S,S)-Bortezomib Hydroxyisopentyl Amide Analog (Bortezomib Hydroxy S,S-Isomer Impurity) BortezomibHydroxy(1S,2S)-Isomer (S,S)-Bortezomib Hydroxyisopentyl Amide Analog Bortezomib EP IMP M N-[(2S)-1-[[(1S)-1-hydroxy-3-methylbutyl]amino]-1-oxo-3-phenylprop N-((S)-1-(((S)-1-Hydroxy-3-Methylbutyl)aMino)-1-oxo-3-phenyl 289472-81-7 Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals