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ChemicalBook >> CAS DataBase List >>[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Structure
[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) structure
CAS No.
909725-62-8
Chemical Name:
[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)
Synonyms
W146;W146 TFA;(R)-3-AMino-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt);(R)-3-AMINO-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W146;[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)
CBNumber:
CB02717540
Molecular Formula:
C18H28F3N2O6P
Molecular Weight:
456.3936906
MDL Number:
MFCD21602904
MOL File:
909725-62-8.mol
Last updated:2025-04-17 18:22:24
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[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Properties

storage temp. Store at -20°C
solubility Methanol: 0.1 mg/ml
form A crystalline solid
color White to off-white
UNSPSC Code 12352211
NACRES NA.25

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 500μg $78 2024-03-01 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 1mg $146 2024-03-01 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 5mg $614 2024-03-01 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 10mg $1071 2024-03-01 Buy
Tocris 3602 W146 ≥98%(HPLC) 909725-62-8 1 $173 2021-12-16 Buy
Product number Packaging Price Buy
10009109 500μg $78 Buy
10009109 1mg $146 Buy
10009109 5mg $614 Buy
10009109 10mg $1071 Buy
3602 1 $173 Buy

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Chemical Properties,Uses,Production

Uses

W146 is a selective antagonists of spingosine-1-phosphate receptor subtype 1.

Biological Activity

W146 acts as an orthosteric antagonist. It is linked to blood lymphopenia and lung edema in mice.

in vivo

W146 (5 mg/kg, ip, prior to AMD3100 administration) pre-treatment shows approximately 8-fold increase of KSL-HSPC mobilization, measured by the CFU-G/M colony forming assays, compared to that in mice treated with AMD3100 alone[3]
The W146-mediated augmentation of KSL-HSPC mobilization is specific, because pretreatment of mice with W140 is unable to produce any effect on AMD3100-stimulated KSL-HSPC mobilization. Injections of W146, W140, JTE013, or Cay10444 do not alter the basal WBC count in mice[3].

Animal Model:Mice (4-6-week-old)[3]
.
Dosage:5 mg/kg.
Administration:IP, 1 hour prior to AMD3100 (ADM) administration.
Result:Significantly increased in KSL-HSPC mobilization compared to that in mice pretreated with dextran followed by AMD3100 administration.

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Preparation Products And Raw materials

Raw materials

Preparation Products

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Suppliers

Global( 33)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes 		1-516-855-7709 info@creative-enzymes.com United States 8748 58
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17687 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961 cdhxsj@163.com China 14603 60
Beijing OKA biological technology co., LTD 010-010-010-62971590 18548936886 jack@oka-vip.com China 6897 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Shanghai Universal Biotech Co.,Ltd 13774214275 zhouzz@univ-bio.com China 25002 58
Supplier Advantage
Creative Enzymes 		58
EMMX Biotechnology LLC 60
Codow Chemical Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
Chengdu Dianchun Technology Co., Ltd 60
Beijing OKA biological technology co., LTD 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
Shanghai Universal Biotech Co.,Ltd 58

909725-62-8([(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate))Related Search:

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N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE

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[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) (R)-3-AMino-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) W146 (R)-3-AMINO-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W146 W146 TFA 909725-62-8 C16H27N2O4PC2HF3O2