ChemicalBook >> CAS DataBase List >>[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)

CAS No.
909725-62-8
Chemical Name:
[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)
Synonyms
W146;W146 TFA;(R)-3-AMino-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt);(R)-3-AMINO-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W146;[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)
CBNumber:
CB02717540
Molecular Formula:
C18H28F3N2O6P
Molecular Weight:
456.3936906
MDL Number:
MFCD21602904
MOL File:
909725-62-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:18
Product description Number Pack Size Price
W146 (trifluoroacetate salt) ≥95% 10009109 500μg $86
W146 (trifluoroacetate salt) ≥95% 10009109 1mg $161
W146 (trifluoroacetate salt) ≥95% 10009109 5mg $676
W146 (trifluoroacetate salt) ≥95% 10009109 10mg $1179
W146 (trifluoroacetate salt) ≥95% 10009109 500μg $78

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Properties

storage temp. Store at -20°C
solubility Methanol: 0.1 mg/ml
form A crystalline solid
color White to off-white
UNSPSC Code 12352211
NACRES NA.25

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 500μg $86 2026-04-30 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 1mg $161 2026-04-30 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 5mg $676 2026-04-30 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 10mg $1179 2026-04-30 Buy
Cayman Chemical 10009109 W146 (trifluoroacetate salt) ≥95% 909725-62-8 500μg $78 2024-03-01 Buy
Product number Packaging Price Buy
10009109 500μg $86 Buy
10009109 1mg $161 Buy
10009109 5mg $676 Buy
10009109 10mg $1179 Buy
10009109 500μg $78 Buy

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Chemical Properties,Uses,Production

Uses

W146 is a selective antagonists of spingosine-1-phosphate receptor subtype 1.

Biological Activity

W146 acts as an orthosteric antagonist. It is linked to blood lymphopenia and lung edema in mice.

in vivo

W146 (5 mg/kg, ip, prior to AMD3100 administration) pre-treatment shows approximately 8-fold increase of KSL-HSPC mobilization, measured by the CFU-G/M colony forming assays, compared to that in mice treated with AMD3100 alone[3]
The W146-mediated augmentation of KSL-HSPC mobilization is specific, because pretreatment of mice with W140 is unable to produce any effect on AMD3100-stimulated KSL-HSPC mobilization. Injections of W146, W140, JTE013, or Cay10444 do not alter the basal WBC count in mice[3].

Animal Model:Mice (4-6-week-old)[3]
.
Dosage:5 mg/kg.
Administration:IP, 1 hour prior to AMD3100 (ADM) administration.
Result:Significantly increased in KSL-HSPC mobilization compared to that in mice pretreated with dextran followed by AMD3100 administration.

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Preparation Products And Raw materials

Raw materials

Preparation Products

[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) Suppliers

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Creative Enzymes
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[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate) (R)-3-AMino-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) (R)-3-AMINO-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W146 W146 TFA W146 909725-62-8 C16H27N2O4PC2HF3O2 C16H27N2O4PCF3COOH