ChemicalBook >> CAS DataBase List >>KN-93 Phosphate
KN-93 Phosphate
- CAS No.
- 1188890-41-6
- Chemical Name:
- KN-93 Phosphate
- Synonyms
- CS-1902;KN 93; KN93;KN-93PHOSPHATE;KN-93 phospate;(E)-KN-93 (phosphate);KN-93 phosphate, >=98%;KN 93 Phosphate (E-form);KN-93 Phosphate USP/EP/BP;(E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate;N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate
- CBNumber:
- CB02729653
- Molecular Formula:
- C26H32ClN2O8PS
- Molecular Weight:
- 599.032641
- MDL Number:
- MFCD03788201
- MOL File:
- 1188890-41-6.mol
Last updated:2023-06-30 15:45:59
| storage temp. | Inert atmosphere,Room Temperature |
|---|---|
| solubility |
DMF:25.0(Max Conc. mg/mL);41.73(Max Conc. mM) DMSO:76.67(Max Conc. mg/mL);127.98(Max Conc. mM) Water:49.33(Max Conc. mg/mL);82.35(Max Conc. mM) |
| form | White to off-white solid. |
| Water Solubility | Soluble in water (10mM) |
| CAS DataBase Reference | 1188890-41-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P405-P501 |
KN-93 Phosphate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 1188890-41-6 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 1188890-41-6 | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 1188890-41-6 | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 21472 | KN-93 (phosphate) ≥98% | 1188890-41-6 | 25mg | $343 | 2024-03-01 | Buy |
| Tocris | 5215 | KN93phosphate ≥98%(HPLC) | 1188890-41-6 | 1 | $141 | 2021-12-16 | Buy |
KN-93 Phosphate Chemical Properties,Uses,Production
Description
KN-93 (phosphate) is a potent and selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII) (Ki = 370 nM), inhibiting both the α- and β-subunits of CaMKII. It does not have significant effects on cAMP-dependent protein kinase, Ca2+/phospholipid-dependent protein kinase, myosin light chain kinase, or Ca2+ phosphodiesterase activity. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 can block voltage-gated potassium (Kv) channels when applied extracellularly, independent of its CaMKII action. More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cells.
Uses
KN 93 Phosphate is a potent and selective inhibitor of Ca2+/calmodulin-dependent protein kinase II.
storage
-20°C
KN-93 Phosphate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 66)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29322 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
1188890-41-6(KN-93 Phosphate)Related Search:
KN-93PHOSPHATE
Benzenesulfonamide, N-[2-[[[(2E)-3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-, phosphate (1:1)
N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-
methoxybenzenesulphonamide phosphate KN-93 Phosphate
KN-93 phosphate, >=98%
KN-93 phospate
N-[2-({[(2E)-3-(4-Chlorophenyl)-2-propen-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate (1:1)
CS-1902
N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate
KN 93; KN93
KN-93 Phosphate USP/EP/BP
(E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate
(E)-KN-93 (phosphate)
KN 93 Phosphate (E-form)
1188890-41-6
C26H29ClN2O4SH3O4P
C26H32ClN2O8PS
Inhibitors