SCIADOPITYSIN
- CAS No.
- 521-34-6
- Chemical Name:
- SCIADOPITYSIN
- Synonyms
- Nsc 45108;SCIADOPITYSIN;Einecs 208-311-5;SCIADOPITYSIN(SH);4',4''',7-Trimethoxyamentoflavone;AMENTOFLAVONE-7,4',4'-TRIMETHYL ETHER;AMENTOFLAVONE-7,4',4''-TRIMETHYL ETHER;AMENTOFLAVONE-7,4',4'''-TRIMETHYL ETHER;Sciadopitysin, 95%, from Ginkgo biloba L.;AMENTOFLAVONE-7,4'',4''-TRIMETHYL ETHER WITH HPLC
- CBNumber:
- CB0273404
- Molecular Formula:
- C33H24O10
- Molecular Weight:
- 580.54
- MDL Number:
- MFCD00017448
- MOL File:
- 521-34-6.mol
- MSDS File:
- SDS
Melting point | 296-298°C |
---|---|
Boiling point | 839.6±65.0 °C(Predicted) |
Density | 1.445±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Soluble in ethanol and methan |
form | powder |
pka | 6.16±0.40(Predicted) |
color | Light yellow |
LogP | 5.500 (est) |
CAS DataBase Reference | 521-34-6 |
FDA UNII | WL44VY201L |
SAFETY
Risk and Safety Statements
Safety Statements | 24/25 |
---|---|
HS Code | 29329990 |
SCIADOPITYSIN price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 27900 | Sciadopitysin | 521-34-6 | 5mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 27900 | Sciadopitysin | 521-34-6 | 50mg | $841 | 2024-03-01 | Buy |
Cayman Chemical | 27900 | Sciadopitysin | 521-34-6 | 10mg | $230 | 2024-03-01 | Buy |
Cayman Chemical | 27900 | Sciadopitysin | 521-34-6 | 25mg | $513 | 2024-03-01 | Buy |
Usbiological | 300938 | Sciadopitysin | 521-34-6 | 20mg | $462 | 2021-12-16 | Buy |
SCIADOPITYSIN Chemical Properties,Uses,Production
Description
Sciadopitysin is a biflavonoid originally isolated from G. biloba and has diverse biological activities. It reduces cytotoxicity induced by amyloid-β (1-42) (Aβ42; ) in PC12 cells (EC50 = 9.84 μM). Sciadopitysin (0.1-10 μM) decreases methylglyoxal-induced insulin secretion, production of reactive oxygen species (ROS), cardiolipin peroxidation, and cytotoxicity in RIN-m5F pancreatic β-cells. It inhibits P-glycoprotein (P-gp; IC50 = 53.42 μM) and increases cellular toxicity of paraquat and paclitaxel in MDR1-MDCKII cells. Sciadopitysin inhibits RANKL-induced mRNA expression of the osteoclast-specific genes CTSK, TRAP, and MMP-9, activation of NF-κB, and osteoclastogenesis in a mouse model of LPS-induced bone loss.
Definition
ChEBI: A biflavonoid that is a 7, 4', 4'''-trimethyl ether derivative of amentoflavone.
target
ROS | MMP(e.g.TIMP) | NO | TNF-α | ATPase | cAMP | Beta Amyloid
SCIADOPITYSIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
View Lastest Price from SCIADOPITYSIN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-02-24 | Sciadopitysin
521-34-6
|
US $0.00 / mg | 20mg | ≥98%(HPLC) | 100 g | Shanghai Standard Technology Co., Ltd. | ||
2019-07-06 | SCIADOPITYSIN
521-34-6
|
US $350.00 / KG | 1KG | 99.5% | 10000kg | Career Henan Chemical Co |
- Sciadopitysin
521-34-6
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
- SCIADOPITYSIN
521-34-6
- US $350.00 / KG
- 99.5%
- Career Henan Chemical Co