Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide Structure
2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide structure
CAS No.
1395048-49-3
Chemical Name:
2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide
Synonyms
M-110;CS-2124;M 110,M110;M-110 >=98% (HPLC);2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide;4-Pyridinecarboxylic acid, 2-[[3-(4-morpholinyl)propyl]amino]-, 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide
CBNumber:
CB02750705
Molecular Formula:
C22H28ClN5O3
Molecular Weight:
445.94
MDL Number:
MOL File:
1395048-49-3.mol
Last updated:2023-09-04 15:50:00
Request For Quotation

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide Properties

Density 1.31±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble25mg/mL, clear
pka 7.46±0.40(Predicted)
form powder
color white to beige

SAFETY

Risk and Safety Statements

WGK Germany  3

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0962 M-110 ≥98% (HPLC) 1395048-49-3 5mg $118 2024-03-01 Buy
Sigma-Aldrich SML0962 M-110 ≥98% (HPLC) 1395048-49-3 25mg $382 2024-03-01 Buy
ChemScene CS-4214 M-110 98.78% 1395048-49-3 5mg $195 2021-12-16 Buy
ChemScene CS-4214 M-110 98.78% 1395048-49-3 10mg $330 2021-12-16 Buy
Crysdot CD31003637 M-110 98+% 1395048-49-3 5mg $49 2021-12-16 Buy
Product number Packaging Price Buy
SML0962 5mg $118 Buy
SML0962 25mg $382 Buy
CS-4214 5mg $195 Buy
CS-4214 10mg $330 Buy
CD31003637 5mg $49 Buy

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide Chemical Properties,Uses,Production

Biochem/physiol Actions

M-110 is a highly isoform-selective, cell permeable and potent ATP-competitive inhibitor of the PIM kinase family that prefers PIM-3. M-110 is an inhibitor of Wnt/β-catenin signaling that act downstream of the symb-catenin destruction complex to inhibit both Wnt-induced and cancer associated constitutive Wnt signaling via destabilization of β-catenin. The compound chelates iron in vitro and in intact cells. M-110 inhibits the proliferation of prostate cancer cell lines with IC50s of 0.6 to 0.9 μM, with no activity on normal human peripheral blood mononuclear cells up to 40 μM.

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide Suppliers

Global( 28)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Guangzhou QiYun Biotechnology Co., Ltd. 020-61288194 61288195 505721671@qq.com China 3868 58
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Cckinase, Inc. +1 (732)236-3202 sales@cckinase.com United States 2738 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Haoyuan Chemexpress Co., Ltd. 61
Sigma-Aldrich 80
Guangzhou QiYun Biotechnology Co., Ltd. 58
Musechem 60
Fan De(Beijing) Biotechnology Co., Ltd. 58
DC Chemicals 58
Cckinase, Inc. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide Spectrum

2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide(1395048-49-3)1HNMR
2-[[3-(4-Morpholinyl)propyl]amino]-4-pyridinecarboxylic acid 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide M-110 CS-2124 4-Pyridinecarboxylic acid, 2-[[3-(4-morpholinyl)propyl]amino]-, 2-[1-(4-chloro-2-hydroxyphenyl)propylidene]hydrazide M-110 >=98% (HPLC) M 110,M110 1395048-49-3