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VERRUCULOGEN

VERRUCULOGEN
VERRUCULOGEN structure
CAS No.
12771-72-1
Chemical Name:
VERRUCULOGEN
Synonyms
tr1;T1R1;TRXR1;GPR70;TAS1R1;NA 209A;GRIM-12;MGC9145;TR-1TOXIN;VERRUCOLOGEN
CBNumber:
CB0294003
Molecular Formula:
C27H33N3O7
Formula Weight:
511.57
MOL File:
12771-72-1.mol

VERRUCULOGEN Properties

Flash point:
2℃
storage temp. 
2-8°C
form 
buffered aqueous solution
FDA UNII
S1P1U6VVZ8
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H302+H312+H332-H319
Precautionary statements  P210-P261-P280-P305+P351+P338-P370+P378-P403+P235
Hazard Codes  T,Xn,F
Risk Statements  23/24/25-36-20/21/22-11
Safety Statements  36/37/39-45-36/37-26-16
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  JH4920000
HS Code  38220090

VERRUCULOGEN price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB2700535 Anti-TAS1R1 (N-terminal) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 12771-72-1 100ul $368 2018-11-23 Buy
Sigma-Aldrich SAB2700382 Anti-TAS1R1 (C-terminal) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 12771-72-1 100ul $368 2018-11-23 Buy
Sigma-Aldrich SAB2700382 Anti-TAS1R1 (C-terminal) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 12771-72-1 100 μL $401 2021-03-22 Buy
Sigma-Aldrich SAB2700535 Anti-TAS1R1 (N-terminal) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 12771-72-1 100 μL $401 2021-03-22 Buy
Cayman Chemical 11351 Verruculogen ≥95% 12771-72-1 1mg $79 2021-03-22 Buy

VERRUCULOGEN Chemical Properties,Uses,Production

Uses

Verruculogen is a tremorgenic mycotoxin, first isolated from Penicillium verruculosum in 1972. The structure was resolved as an indole alkaloid in 1974. Verruculogen is produced by several species of Penicillium and Aspergillus and its presence is a useful taxonomic phenotypic marker. The tremorgenic action of verruculogen is associated with increases in spontaneous glutamate and aspartate release, decreases in GABA levels and, at toxic doses, an increase in the number and decrease in the affinity of DHP receptors in rat cortex. In in vitro guinea pig ileum preparations, verruculogen causes an increase in contractile responses due to electrical field stimulation, attributed to enhancement of acetylcholine from presynaptic nerve terminals. Verruculogen also inhibits Ca2+-activated K+ channels, and is a cell cycle inhibitor blocking division at the M phase.

Uses

Verruculogen is a tremorgenic mycotoxin isolated from species of Penicillium, Aspergillus, and other fungi. It selectively inhibits the activation of Maxi-K potassium channels by charybdotoxin with a K1/2 value of 170 nM. Verruculogen also promotes the release of excitatory neurotransmitters when injected directly into the brain of rats and, at high doses, arrests mouse mammary carcinoma cells in M phase of the cell cycle (MIC = 12.2 μM).[Cayman Chemical]

Definition

ChEBI: An organic heterohexacyclic compound that is a mycotoxic indole alkaloid isolated from Penicillium and Aspergillus species.

VERRUCULOGEN Preparation Products And Raw materials

Raw materials

Preparation Products


VERRUCULOGEN Suppliers

Global( 74)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26762 60
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
Target Molecule Corp
18019718960 781-999-5354
marketing@targetmol.com United States 19232 58
Career Henan Chemica Co
13203830695 0371-86658258
0371-86658258 Laboratory@coreychem.com CHINA 30290 58
BOC Sciences
16314854226
inquiry@bocsci.com United States 19674 58
Nanjing Shizhou Biology Technology Co.,Ltd 13675144456 025-85560043-
025-85563444 sean.lv@synzest.com China 11452 58
J & K SCIENTIFIC LTD. 400-666-7788 010-82848833-
86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 821-50328103-801
86-21-50328109 3bsc@sina.com China 15877 69
Shanghai Tauto Biotech Co., Ltd. 021-51320588
0086-21-51320502 tauto@tautobiotech.com China 4041 66
ChemStrong Scientific Co.,Ltd 15920483169 0755-66853366-
sales@chem-strong.com China 26487 56

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