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Estradiol valerate

Estradiol valerate
Estradiol valerate structure
CAS No.
979-32-8
Chemical Name:
Estradiol valerate
Synonyms
Nuvelle;femogex;pharlon;estraval;Climaval;Valergen;deladiol;atladiol;NSC 17590;neofollin
CBNumber:
CB0300193
Molecular Formula:
C23H32O3
Formula Weight:
356.51
MOL File:
979-32-8.mol

Estradiol valerate Properties

Melting point:
144°C
Boiling point:
438.83°C (rough estimate)
Density 
1.1024 (rough estimate)
refractive index 
1.4700 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Practically insoluble in water, soluble in alcohol.
form 
neat
pka
10.25±0.60(Predicted)
Merck 
13,3738
BRN 
2480357
InChIKey
RSEPBGGWRJCQGY-RBRWEJTLSA-N
CAS DataBase Reference
979-32-8(CAS DataBase Reference)
FDA UNII
OKG364O896
NCI Drug Dictionary
estradiol valerate
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H360
Precautionary statements  P201-P280-P308+P313
Hazard Codes  T
Risk Statements  60-61
Safety Statements  53-45
WGK Germany  3
RTECS  KG5793000
HS Code  29372390

Estradiol valerate price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E1631 β-Estradiol 17-valerate ≥98% 979-32-8 1g $183 2021-03-22 Buy
Sigma-Aldrich Y0000046 Estradiol valerate European Pharmacopoeia (EP) Reference Standard 979-32-8 $190 2021-03-22 Buy
Sigma-Aldrich Y0001823 Estradiol valerate for system suitability European Pharmacopoeia (EP) Reference Standard 979-32-8 $190 2021-03-22 Buy
Sigma-Aldrich 1254009 Estradiol valerate United States Pharmacopeia (USP) Reference Standard 979-32-8 100mg $366 2021-03-22 Buy
Cayman Chemical 22221 β-Estradiol 17-valerate ≥98% 979-32-8 500mg $65 2021-03-22 Buy

Estradiol valerate Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Originator

Delestrogen,Squibb,US,1954

Uses

Estradiol (E888000) derivative. An estrogen.

Manufacturing Process

2.3 parts of estradiol are mixed with 12 parts of pyridine and 10 parts of nvaleric anhydride and the mixture is heated for some time at 115°C in the oil bath. The cooled solution is mixed with 250 parts of water, whereupon an oil separates; this is extracted with ether. The separated ethereal solution is washed successively with N sulfuric acid, water, N sodium carbonate solution and water and then dried. The ether is then removed and the residue purified by distillation in a high vacuum. The estradiol di-n-valerate forms a yellowish oil according to US Patent 2,205,627.
1 part of estradiol-3,17-n-divalerianate (boiling point at 0.01 mm = 220° to 230°C bath temperature; made, e.g., by the action of n-valeric anhydride on a solution of estradiol in pyridine) is mixed with 50 parts of a solution of 0.5% strength of potassium carbonate in methyl alcohol of 95% strength, and the whole is stirred for some time at 20°C. The oily n-di-valerianate passes gradually into solution. The solution is neutralized and the precipitate is produced by the addition of about 200 parts of water. This finely crystalline product is filtered and washed successively with water, dilute sodium carbonate solution and again with water. It may be further purified by crystallization from a mixture of methyl alcohol and water. The estradiol-17- mono-n-valerianate melts at 144° to 145°C according to US Patent 2,233,025.

brand name

Delestrogen (King).

Therapeutic Function

Estrogen

Safety Profile

Suspected carcinogen with carcinogenic and teratogenic data. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also ESTRADIOL.

Estradiol valerate Preparation Products And Raw materials

Raw materials

Preparation Products


Estradiol valerate Suppliers

Global( 297)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Rixing Chemical CO.,LTD
13237129059
- info@rixingchemi.com CHINA 229 55
Hebei Bonster Technology Co.,Limited
+86-13315996897
0086-13315996897 Wendy@bsterltd.com CHINA 998 58
Hebei Lingding Biological Technology Co., Ltd
19933155420
sales1@hbldbiotech.com CHINA 963 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21022 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Guangzhou PI PI Biotech Inc
+8618371201331
020-81716319 sales@pipitech.com;87478684@qq.com China 3245 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
02783214688 bruce@xrdchem.cn CHINA 567 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29959 58

View Lastest Price from Estradiol valerate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-27 Estradiol valerate
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-10-27 Estradiol valerate
979-32-8
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-10-20 Estradiol valerate
979-32-8
US $70.00 / KG 1KG 99% 9000kg/per week Hebei Lingding Biological Technology Co., Ltd

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