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3-METHYL-1H-INDAZOLE

CAS No.
3176-62-3
Chemical Name:
3-METHYL-1H-INDAZOLE
Synonyms
3-METHYL-1H-INDAZOLE;1H-Indazole, 3-methyl-;Benzenamine,N,N,3,9-tetramethyl-;1-Propanone,1-(3,9-dichlorophenyl)-
CBNumber:
CB0303785
Molecular Formula:
C8H8N2
Molecular Weight:
132.16
MDL Number:
MFCD00601361
MOL File:
3176-62-3.mol
MSDS File:
SDS
Last updated:2024-02-26 10:17:20

3-METHYL-1H-INDAZOLE Properties

Melting point 113°C
Boiling point 234.08°C (rough estimate)
Density 1.1083 (rough estimate)
refractive index 1.6013 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 14.39±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H317-H319-H335
Precautionary statements  P261-P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HS Code  2933998090

3-METHYL-1H-INDAZOLE price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M336748 3-Methyl-1H-indazole 3176-62-3 500mg $45 2021-12-16 Buy
Matrix Scientific 072395 3-Methyl-1H-indazole 95+% 3176-62-3 5g $78 2021-12-16 Buy
Matrix Scientific 072395 3-Methyl-1H-indazole 95+% 3176-62-3 1g $24 2021-12-16 Buy
SynQuest Laboratories 3H32-1-B4 3-Methyl-1H-indazole 3176-62-3 250mg $33 2021-12-16 Buy
SynQuest Laboratories 3H32-1-B4 3-Methyl-1H-indazole 3176-62-3 1g $100 2021-12-16 Buy
Product number Packaging Price Buy
M336748 500mg $45 Buy
072395 5g $78 Buy
072395 1g $24 Buy
3H32-1-B4 250mg $33 Buy
3H32-1-B4 1g $100 Buy

3-METHYL-1H-INDAZOLE Chemical Properties,Uses,Production

Description

3-Methyl-1H-indazole is a heterocyclic alkyl compound containing nitrogen and three methyl groups. It is used as an intermediate in the synthesis of other compounds. It has been shown to have anti-inflammatory properties in vitro. It also inhibits neutrophil chemotaxis and may be used to treat inflammatory diseases such as trigeminal neuralgia or heart disease. 3-Methyl-1H-indazole has also been shown to inhibit histamine H3 receptor activity, which may account for its effects on eye diseases and bladder cancer.

Uses

3-Methyl-1H-indazole is an intermediate compound. It can be used as an organic synthesis reagent for the preparation of 3-methyl-1H-indazol-5-amine and 3-methyl-5-nitro-1H-indazole compounds. In addition, the 3-Methyl-1H-indazole derivatives (1a-1d and 2a-2d) have antimicrobial effects, both having antibacterial activity against Bacillus subtilis and Escherichia coli[1].

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 25, p. 1817, 1988 DOI: 10.1002/jhet.5570250641
Synthesis, p. 982, 1984

References

[1] FARRUKH SHAIKH. Synthesis and evaluation of antibacterial activity of novel 3-methyl-1H-indazole derivatives[J]. Intelligent Pharmacy, 2024. DOI:10.1016/j.ipha.2023.09.003.

551-93-9
3176-62-3
Synthesis of 3-METHYL-1H-INDAZOLE from 2-Aminoacetophenone

3-METHYL-1H-INDAZOLE Preparation Products And Raw materials

Global( 141)Suppliers
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ROSEWA HOLDING GROUP CO.,LIMITED
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CONIER CHEM AND PHARMA LIMITED
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Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58

View Lastest Price from 3-METHYL-1H-INDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-METHYL-1H-INDAZOLE pictures 2019-07-06 3-METHYL-1H-INDAZOLE
3176-62-3
US $1.00 / KG 1KG 95% 500KG Career Henan Chemical Co

3-METHYL-1H-INDAZOLE Spectrum

3-METHYL-1H-INDAZOLE 1H-Indazole, 3-methyl- 1-Propanone,1-(3,9-dichlorophenyl)- Benzenamine,N,N,3,9-tetramethyl- 3176-62-3 Indazole