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2-Morpholinoethanol

2-Morpholinoethanol structure

CAS No.: 622-40-2

Chemical Name:: 2-Morpholinoethanol

Synonyms: 2-Morpholinoethan-1-ol;4-MORPHOLINEETHANOL;2-MORPHOLIN-4-YL-ETHANOL;4-(2-HYDROXYETHYL)MORPHOLINE;N-(2-HYDROXYETHYL)MORPHOLINE;NSC 1946;AKOS MSC-0730;MORPHOLINOETHANOL;AKOS BBS-00004369;Morpholine ethanol

CBNumber:: CB0304252

Molecular Formula:: C6H13NO2

Molecular Weight:: 131.17

MDL Number:: MFCD00006180

MOL File:: 622-40-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 17:35:14

Product description	Number	Pack Size	Price
4-(2-Hydroxyethyl)morpholine ReagentPlus , 99%	H28203	5g	$48.8
4-(2-Hydroxyethyl)morpholine ReagentPlus , 99%	H28203	100g	$54.7
4-(2-Hydroxyethyl)morpholine >99.0%(GC)	H0244	25mL	$21
4-(2-Hydroxyethyl)morpholine >99.0%(GC)	H0244	100mL	$31
4-Morpholineethanol	TRC-M723750-5G	5g	$70
More product size

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2-Morpholinoethanol Properties

Melting point	-1 °C
Boiling point	227 °C757 mm Hg(lit.)
Density	1.083 g/mL at 25 °C(lit.)
vapor pressure	2.44-7Pa at 20-25℃
refractive index	n20/D 1.476(lit.)
Flash point	211 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Liquid
pka	14.88±0.10(Predicted)
color	Clear colorless to yellow
PH	10.7 (100g/l, H2O, 20℃)
explosive limit	1.5-9.8%(V)
Water Solubility	miscible
BRN	104375
Henry's Law Constant	1.4×10³ mol/(m³Pa) at 25℃, Du et al. (2017)
InChI	1S/C6H13NO2/c8-4-1-7-2-5-9-6-3-7/h8H,1-6H2
InChIKey	KKFDCBRMNNSAAW-UHFFFAOYSA-N
SMILES	OCCN1CCOCC1
LogP	-1.32 at 25℃
CAS DataBase Reference	622-40-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	LY5IL94D3K
NIST Chemistry Reference	4-Morpholineethanol(622-40-2)
EPA Substance Registry System	4-Morpholineethanol (622-40-2)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280-P305+P351+P338-P337+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

WGK Germany

RTECS

QE3510000

10-23

TSCA

TSCA listed

HS Code

29349990

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2

REACH Registrations

Active

NFPA 704

	1
		0

2-Morpholinoethanol price More Price(52)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H28203	4-(2-Hydroxyethyl)morpholine ReagentPlus , 99%	622-40-2	5g	$48.8	2026-04-30	Buy
Sigma-Aldrich	H28203	4-(2-Hydroxyethyl)morpholine ReagentPlus , 99%	622-40-2	100g	$54.7	2026-04-30	Buy
TCI Chemical	H0244	4-(2-Hydroxyethyl)morpholine >99.0%(GC)	622-40-2	25mL	$21	2026-04-30	Buy
TCI Chemical	H0244	4-(2-Hydroxyethyl)morpholine >99.0%(GC)	622-40-2	100mL	$31	2026-04-30	Buy
TRC	TRC-M723750-5G	4-Morpholineethanol	622-40-2	5g	$70	2026-06-03	Buy

Product number	Packaging	Price	Buy
H28203	5g	$48.8	Buy
H28203	100g	$54.7	Buy
H0244	25mL	$21	Buy
H0244	100mL	$31	Buy
TRC-M723750-5G	5g	$70	Buy

2-Morpholinoethanol Chemical Properties,Uses,Production

Chemical Properties

2-Morpholinoethanol is a transparent colorless to yellow liquid. It is used as an organic chemical synthesis intermediate.

Uses

4-(2-Hydroxyethyl)morpholine is a morphiline derivative used in the preparation of ester prodrugs of naproxen. 4-(2-Hydroxyethyl)morpholine was also shown to induce repair in rat hepatocyte primary cu lture/DNA.

Definition

ChEBI: 2-Morpholinoethanol is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group. It is a primary alcohol, a tertiary amino compound and a member of morpholines.

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 467, 1987 DOI: 10.1021/jo00379a035

Flammability and Explosibility

Non flammable

References

[1] Journal of the Indian Chemical Society, 1989, vol. 66, # 5, p. 316 - 318
[2] Patent: WO2014/12360, 2014, A1. Location in patent: Paragraph 00498
[3] Patent: US2015/87639, 2015, A1. Location in patent: Paragraph 0849; 0850
[4] Patent: TWI607995, 2017, B. Location in patent: Page/Page column 180
[5] Journal of Organic Chemistry, 2018, vol. 83, # 24, p. 15333 - 15346

2-Morpholinoethanol Preparation Products And Raw materials

Raw materials

Morpholine Triethanolamine 2-Bromoethanol Acetonitrile Potassium carbonate

Preparation Products

4-(2-Chloroethyl)morpholine hydrochloride Mycophenolate mofetil 4-(2-Chloroethyl)morpholine 2-N-MORPHOLINOETHYL ACRYLATE 4-[2-(2-NITROPHENOXY)ETHYL]MORPHOLINE

4-Morpholineethanamine, N-2-pyridinyl- 2-N-Morpholinoethyl methacrylate 2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoate hydrochloride

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2-Morpholinoethanol Suppliers

Global( 405)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Fengmu Trading Co., Ltd.	+8613393234347	Lyla@fengmuchem.com	China	2943	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16512	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6366	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58

Supplier	Advantage
Hebei Fengmu Trading Co., Ltd.	58
Hebei Yanxi Chemical Co., Ltd.	58
airuikechemical co., ltd.	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Xiamen AmoyChem Co., Ltd	58
Shandong chuangyingchemical Co., Ltd.	58
BOC Sciences	58

View Lastest Price from 2-Morpholinoethanol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-02	2-Morpholinoethanol 622-40-2	$2.00-5.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-06-20	2-Morpholinoethanol 622-40-2		1kg	99%	100tons	Hebei Yanxi Chemical Co., Ltd.
2025-05-26	2-Morpholinoethanol 622-40-2	$7.00	1kg	0.99	10000	Hebei Fengjia New Material Co., Ltd

2-Morpholinoethanol
622-40-2
$2.00-5.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

2-Morpholinoethanol
622-40-2
99%
Hebei Yanxi Chemical Co., Ltd.

2-Morpholinoethanol
622-40-2
$7.00
0.99
Hebei Fengjia New Material Co., Ltd

2-Morpholinoethanol Spectrum

2-Morpholinoethanol(622-40-2)MS 2-Morpholinoethanol(622-40-2)¹HNMR 2-Morpholinoethanol(622-40-2)¹³CNMR 2-Morpholinoethanol(622-40-2)IR1 2-Morpholinoethanol(622-40-2)IR2 2-Morpholinoethanol(622-40-2)Raman

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