Sacubitril Sodium Salt

Sacubitril Sodium Salt structure

CAS No.: 149690-05-1

Chemical Name:: Sacubitril Sodium Salt

Synonyms: Sacubitril sodium;Valsartan Sodium;Thacubatra sodium;AHU-377 sodium salt;Sacubitril Sodium Salt;AHU-377 (Sacubitril free base);Sodium,4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate;(αR,γS)- γ-[(3-Carboxy -1-oxopropyl) amino]-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester sodium salt

CBNumber:: CB03069990

Molecular Formula:: C24H28NNaO5

Molecular Weight:: 433.47259

MDL Number:: MFCD32004488

MOL File:: 149690-05-1.mol

MSDS File:: SDS

Last updated:2023-05-04 15:14:23

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Sacubitril Sodium Salt Properties

Melting point	163-165°C
storage temp.	-20°C, Hygroscopic
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic
FDA UNII	MOP72GEP8Z

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H413
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P

Sacubitril Sodium Salt price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
DC Chemicals	DC32235	Sacubitrilsodium	149690-05-1	250mg	$700	2021-12-16	Buy
DC Chemicals	DC32235	Sacubitrilsodium	149690-05-1	1g	$1400	2021-12-16	Buy

Product number	Packaging	Price	Buy
DC32235	250mg	$700	Buy
DC32235	1g	$1400	Buy

Sacubitril Sodium Salt Chemical Properties,Uses,Production

Uses

Sacubitril Sodium Salt is a salt of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

Sacubitril Sodium Salt synthesis

Synthesis of Sacubitril Sodium Salt from Succinic anhydride and (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

Sacubitril Sodium Salt Preparation Products And Raw materials

Raw materials

AHU-377 (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Succinic anhydride

Preparation Products

Sacubitril Sodium Salt Suppliers

Global( 50)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Lewoo Pharmatech(Shanghai)Co.,Ltd	+8615800805830	miao@lewoopharma.com.cn	China	141	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	31902	60
BOC Sciences	+16314854226	inquiry@bocsci.com	United States	19588	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15522	58
InvivoChem	+1-708-3101919	sales@invivochem.net	United States	6395	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	sales@tnjchem.com	China	25363	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24788	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19976	58
ZHEJIANG JIUZHOU CHEM CO., LTD	+86-0576225566889 +86-13454675544	admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com	China	21846	58

Supplier	Advantage
Lewoo Pharmatech(Shanghai)Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
ATK CHEMICAL COMPANY LIMITED	60
BOC Sciences	58
AFINE CHEMICALS LIMITED	58
InvivoChem	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
LEAP CHEM CO., LTD.	58
TargetMol Chemicals Inc.	58
ZHEJIANG JIUZHOU CHEM CO., LTD	58

Sacubitril Sodium Salt Valsartan Sodium sodium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate AHU-377 (Sacubitril free base) Sacubitril sodium AHU-377 sodium salt Sodium,4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate Thacubatra sodium (αR,γS)- γ-[(3-Carboxy -1-oxopropyl) amino]-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester sodium salt 149690-05-1