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Deferiprone

Deferiprone
Deferiprone structure
CAS No.
30652-11-0
Chemical Name:
Deferiprone
Synonyms
L1;DMHP;CP20;Kelfer;DEFERIDONE;DEFERIPRON;DEFERIPRONE;deferiprone(DFP);TIMTEC-BB SBB006753;cp20(chelatingagent)
CBNumber:
CB0308124
Molecular Formula:
C7H9NO2
Formula Weight:
139.15
MOL File:
30652-11-0.mol

Deferiprone Properties

Melting point:
272-275 °C(lit.)
Boiling point:
255.1°C (rough estimate)
Density 
1.1997 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
-20°C Freezer
form 
Crystalline Powder or Needles
pka
pKa1 3.3, pKa2 9.7(at 25℃)
color 
White to off-white
Water Solubility 
Soluble in hot water
Merck 
14,2859
InChIKey
TZXKOCQBRNJULO-UHFFFAOYSA-N
CAS DataBase Reference
30652-11-0(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  UU7785940
HS Code  29333990
Toxicity LD50 i.p. in rats, mice: 650 mg/kg, 0.8-1.0 g/kg; i.g. in rats: 2.0-3.0 g/kg (Kontoghiorghes, 1995)

Deferiprone price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 379409 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone 98% 30652-11-0 5g $62 2018-11-13 Buy
Sigma-Aldrich 379409 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone 98% 30652-11-0 25g $225 2018-11-13 Buy
TCI Chemical H0944 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone >98.0%(T) 30652-11-0 5g $69 2018-11-22 Buy
TCI Chemical H0944 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone >98.0%(T) 30652-11-0 25g $202 2018-11-22 Buy
Cayman Chemical 20387 Deferiprone ≥95% 30652-11-0 1g $25 2018-11-19 Buy

Deferiprone Chemical Properties,Uses,Production

Description

Deferiprone, the first oral iron chelator, was marketed in India for the management of thalassaemia. Patients with thalassaemia, a blood related genetic disorder, require life time transfusion which causes excessive deposition of iron in liver and spleen, subsequent damage to organs and eventually death unless iron is removed by a chelator. Deferiprone is a potent iron chelator that mobilizes excessive iron from iron storage proteins ferritin and hemosiderin, from iron saturated transferrin and lactoferrin, but not from hemoglobin. The deferiprone-iron complex is excreted in urine and bile. Deferiprone was reportedly well accepted by patients and no hematological toxicity was observed. Deferiprone has also been demonstrated as an effective and safe chelator in the mobilization of aluminum.

Chemical Properties

White Needles

Originator

Cipla (India)

Uses

A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro

Uses

iron chelating agent

Definition

ChEBI: A member of the class of 4-pyridones that is pyridin-4(1H)-one substituted at positions 1 and 2 by methyl groups and at position 3 by a hydroxy group. A lipid-soluble iron-chelator used for treatment of thalassaemia.

brand name

Kelfer

Deferiprone Preparation Products And Raw materials

Raw materials

Preparation Products


Deferiprone Suppliers

Global( 145)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hainan Xiyuan Chemical Technology Co., Ltd.
+86-15008981366
15008981366@163.com CHINA 9 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19918 60
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32447 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2884 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Shenzhen Nexconn Pharmatechs Ltd
15013857715
admin@nexconn.com CHINA 3195 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23980 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12231 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35440 58

View Lastest Price from Deferiprone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-06-21 Deferiprone
30652-11-0
US $1.00 / KG 1KG 99% Customized career henan chemical co

Deferiprone Spectrum


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