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Proteasome Inhibitor XVI

Proteasome Inhibitor XVI Structure
Proteasome Inhibitor XVI structure
CAS No.
389064-25-9
Chemical Name:
Proteasome Inhibitor XVI
Synonyms
Proteasome Inhibitor XVI;AdaAhxLVS - CAS 389064-25-9 - Calbiochem;L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]-
CBNumber:
CB03121496
Molecular Formula:
C50H88N6O8S
Molecular Weight:
933.33
MDL Number:
MOL File:
389064-25-9.mol
Last updated:2023-04-23 13:52:06
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Proteasome Inhibitor XVI Properties

Boiling point 1161.4±65.0 °C(Predicted)
Density 1.096±0.06 g/cm3(Predicted)
storage temp. -20C
form Off-white powder
pka 13.41±0.46(Predicted)

Proteasome Inhibitor XVI price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 114802 AdaAhx₃L₃VS - CAS 389064-25-9 - Calbiochem A potent, covalent, cell-permeable, irreversible inhibitor of chymotrypsin-like (50-100 nM), trypsin-like (1-5 μM), and PGPH (0.5-1 μM) activities of the 20S proteasome. 389064-25-9 250μg $390 2024-03-01 Buy
Product number Packaging Price Buy
114802 250μg $390 Buy

Proteasome Inhibitor XVI Chemical Properties,Uses,Production

General Description

A cell-permeable, peptide vinyl sulfone that acts as a potent, irreversible inhibitor of proteasome activity. Covalently modifies the catalytically active β-subunits of the proteasome. Shown to inhibit the chymotrypsin-like (10-50 nM), trypsin-like (1-5 μM), and the peptidyl glutamyl peptide hydrolyzing (PGPH) (0.5-1 μM) activities of purified 20S proteasomes from rabbit muscle. Inhibits proteasomal degradation of deglycosylated MHC HLA-A2 heavy chain in US11+ cells (~50 μM).

Biochem/physiol Actions

Cell permeable: yes

Proteasome Inhibitor XVI Preparation Products And Raw materials

Raw materials

Preparation Products

Proteasome Inhibitor XVI Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd 		+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518 sales@alabiochem.com China 995 59
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Alabiotech Inc. 001-619-354-5251 sales@alabiotech-e.com United States 972 60
Alpha Biopharmaceuticals Co., Ltd 0411-39042497 sales@alphabiopharm.com China 1951 58
Supplier Advantage
Alpha Biopharmaceuticals Co., Ltd 		58
Nextpeptide Inc 		58
Alabiochem Tech.Co., Ltd. 59
Sigma-Aldrich 80
Alabiotech Inc. 60
Alpha Biopharmaceuticals Co., Ltd 58
Proteasome Inhibitor XVI AdaAhxLVS - CAS 389064-25-9 - Calbiochem L-Leucinamide, N-[1-oxo-6-[[1-oxo-6-[[1-oxo-6-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]hexyl]amino]hexyl]amino]hexyl]-L-leucyl-N-[(1S)-3-methyl-1-[(1E)-2-(methylsulfonyl)ethenyl]butyl]- 389064-25-9 C50H88N6O8S