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ChemicalBook >> CAS DataBase List >>1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Structure
1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- structure
CAS No.
1021456-82-5
Chemical Name:
1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-
Synonyms
Palonosetron USP RC B;Palonosetron Impurity 2;Palonosetron USP Impurity B;Dehydro N-Oxide Palonosetron;Dehydro palonosetron N-oxide;Palonosetron USP Related Compound B;Palonosetron USP Related Compound B HCl;Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide);Palonosetron Impurity 13 (Palonosetron USP Related Compound B);(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide
CBNumber:
CB03133165
Molecular Formula:
C19H22N2O2
Molecular Weight:
310.39
MDL Number:
MFCD32671828
MOL File:
1021456-82-5.mol
Last updated:2023-05-15 10:43:34
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1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Properties

solubility Methanol (Slightly), Water (Slightly)
form Solid
pka 4.72±0.40(Predicted)
color Off-White to Pale Yellow
FDA UNII FZY2QC85ZS

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
HS Code  2933790002

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P165820 Palonosetron-3-eneN-Oxide 1021456-82-5 10mg $215 2021-12-16 Buy
Medical Isotopes, Inc. 85079 Palonosetron-3-eneN-oxide 1021456-82-5 10mg $390 2021-12-16 Buy
Product number Packaging Price Buy
P165820 10mg $215 Buy
85079 10mg $390 Buy

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Chemical Properties,Uses,Production

Uses

Palonosetron-3-ene N-Oxide is an impurity of Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- Suppliers

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
sgtlifesciences pvt ltd 		+8617013299288 dj@sgtlifesciences.com China 12382 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 50000 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Guangzhou PI PI Biotech Inc +86-020-81716320 +86-13602409664 Sales@pipitech.com China 3635 55
Beijing Fuchen Technology Co., Ltd 15652759959 623245911@qq.com China 461 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-52878169 15701683040 sales@bjcomparison.com China 4683 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Supplier Advantage
Standardpharm Co. Ltd. 		58
Career Henan Chemica Co 		58
sgtlifesciences pvt ltd 		58
GIHI CHEMICALS CO.,LIMITED 		58
China National Standard Pharmaceutical Corporation Limited 		58
Guangzhou PI PI Biotech Inc 55
Beijing Fuchen Technology Co., Ltd 58
BOC Sciences 65
Beijing Comparison Pharmaceutical Technology Co., Ltd 58
ChemStrong Scientific Co.,Ltd 56

1021456-82-5(1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-)Related Search:

(6S)-Hydroxy (S,S)-Palonosetron 6-Oxo-Palonosetron (6R)-Hydroxy (S,S)-Palonosetron 6-Hydroxy Palonosetron GIIYMZHZCASHNL-NVXWUHKLSA-N
(1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxaMide Palonosetron N-Oxide 1H-Benz[de]isoquinolin-1-one,2-(3S)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aR)- Palonosetron Impurity 9 Palonosetron
(3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]Methyl]-1-azabicyclo[2.2.2]octan-3-aMine 1H-Benz[de]isoquinolin-1-one,2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aS)- RS 42358-197 PALONOSETRON HCL Palonosetron Impurity 8
Palonosetron impurity (S,R)-Palonosetron Hydrochloride (R,S)-Palonosetron Hydrochloride

1of4

Palonosetron Impurity 2 Palonosetron Related Compound B ((3S)-3-(1-Oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinucl (1492233) Dehydro N-Oxide Palonosetron (S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide HCl Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide) Dehydro palonosetron N-oxide Palonosetron USP Related Compound B HCl (S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide Palonosetron USP Related Compound B Palonosetron USP RC B 2-[(3S)-1-oxido-1-azoniabicyclo[2.2.2]octan-3-yl]-5,6-dihydro-4H-benzo[de]isoquinolin-1-one Palonosetron USP Impurity B Palonosetron Impurity 13 (Palonosetron USP Related Compound B) 1021456-82-5