ChemicalBook >> CAS DataBase List >>glucagon receptor antagonists-4
glucagon receptor antagonists-4
- CAS No.
- 1393124-08-7
- Chemical Name:
- glucagon receptor antagonists-4
- Synonyms
- CS-2641;PF6291874;GCGR-IN-17;PF-06291874 >=98% (HPLC);Glucagon Receptor Antagonist 4;lucagon receptor antagonists-4;glucagon receptor antagonists-4;PF06291874;PF-06291874;PF 06291874;PF-06291874(glucagon receptor antagonists-4);N-{4-[(1S)-1-{3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]benzoyl}-β-alanine
- CBNumber:
- CB03133347
- Molecular Formula:
- C26H28F3N3O4
- Molecular Weight:
- 503.51
- MDL Number:
- MFCD30343861
- MOL File:
- 1393124-08-7.mol
Last updated:2023-05-21 10:59:17
| Boiling point | 675.0±55.0 °C(Predicted) |
|---|---|
| Density | 1.27±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 50mg/mL; DMSO: 50mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL; Ethanol: 0.5mg/mL |
| form | A crystalline solid |
| pka | 4.28±0.10(Predicted) |
| FDA UNII | CGY4I8F278 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
glucagon receptor antagonists-4 price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 22164 | Glucagon Receptor Antagonist 4 | 1393124-08-7 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 22164 | Glucagon Receptor Antagonist 4 | 1393124-08-7 | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 22164 | Glucagon Receptor Antagonist 4 | 1393124-08-7 | 10mg | $169 | 2024-03-01 | Buy |
| Cayman Chemical | 22164 | Glucagon Receptor Antagonist 4 | 1393124-08-7 | 25mg | $381 | 2024-03-01 | Buy |
| TRC | P294103 | PF-06291874 | 1393124-08-7 | 10mg | $315 | 2021-12-16 | Buy |
glucagon receptor antagonists-4 Chemical Properties,Uses,Production
Uses
PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.
glucagon receptor antagonists-4 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 58)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
glucagon receptor antagonists-4
N-{4-[(1S)-1-{3,5-Dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]benzoyl}-β-alanine
lucagon receptor antagonists-4
Glucagon Receptor Antagonist 4
GCGR-IN-17
PF06291874;PF-06291874;PF 06291874
PF6291874
CS-2641
PF-06291874(glucagon receptor antagonists-4)
β-Alanine, N-[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy]butyl]benzoyl]-
PF-06291874 >=98% (HPLC)
inhibit,Inhibitor,glucagon,bioavailability,Glucagon Receptor,PF 06291874,Glucagon receptor antagonists4,clearance,GCGR,PF-06291874,oral,PF06291874,Glucagon receptor antagonists 4
1393124-08-7
API